X Chromosome Inactivation
"X Chromosome Inactivation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.
Descriptor ID |
D049951
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MeSH Number(s) |
G05.308.203.249.970
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Concept/Terms |
X Chromosome Inactivation- X Chromosome Inactivation
- Chromosome Inactivation, X
- Inactivation, X Chromosome
- Lyonization
- X-Inactivation
- X Inactivation
- Inactivation, X
- X Inactivations
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Below are MeSH descriptors whose meaning is more general than "X Chromosome Inactivation".
Below are MeSH descriptors whose meaning is more specific than "X Chromosome Inactivation".
This graph shows the total number of publications written about "X Chromosome Inactivation" by people in this website by year, and whether "X Chromosome Inactivation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
2007 | 1 | 1 | 2 |
2009 | 3 | 0 | 3 |
2012 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "X Chromosome Inactivation" by people in Profiles.
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Bredemeyer KR, Seabury CM, Stickney MJ, McCarrey JR, vonHoldt BM, Murphy WJ. Rapid Macrosatellite Evolution Promotes X-Linked Hybrid Male Sterility in a Feline Interspecies Cross. Mol Biol Evol. 2021 12 09; 38(12):5588-5609.
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Sosa E, Flores L, Yan W, McCarrey JR. Escape of X-linked miRNA genes from meiotic sex chromosome inactivation. Development. 2015 Nov 01; 142(21):3791-800.
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Grant J, Mahadevaiah SK, Khil P, Sangrithi MN, Royo H, Duckworth J, McCarrey JR, VandeBerg JL, Renfree MB, Taylor W, Elgar G, Camerini-Otero RD, Gilchrist MJ, Turner JM. Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation. Nature. 2012 Jul 12; 487(7406):254-8.
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Yan W, McCarrey JR. Sex chromosome inactivation in the male. Epigenetics. 2009 Oct 01; 4(7):452-6.
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Mahadevaiah SK, Royo H, VandeBerg JL, McCarrey JR, Mackay S, Turner JM. Key features of the X inactivation process are conserved between marsupials and eutherians. Curr Biol. 2009 Sep 15; 19(17):1478-84.
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Song R, Ro S, Michaels JD, Park C, McCarrey JR, Yan W. Many X-linked microRNAs escape meiotic sex chromosome inactivation. Nat Genet. 2009 Apr; 41(4):488-93.
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Namekawa SH, VandeBerg JL, McCarrey JR, Lee JT. Sex chromosome silencing in the marsupial male germ line. Proc Natl Acad Sci U S A. 2007 Jun 05; 104(23):9730-5.
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Davidow LS, Breen M, Duke SE, Samollow PB, McCarrey JR, Lee JT. The search for a marsupial XIC reveals a break with vertebrate synteny. Chromosome Res. 2007; 15(2):137-46.
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Namekawa SH, Park PJ, Zhang LF, Shima JE, McCarrey JR, Griswold MD, Lee JT. Postmeiotic sex chromatin in the male germline of mice. Curr Biol. 2006 Apr 04; 16(7):660-7.