"Inteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The internal fragments of precursor proteins (INternal proTEINS) that are autocatalytically removed by PROTEIN SPLICING. The flanking fragments (EXTEINS) are ligated forming mature proteins. The nucleic acid sequences coding for inteins are considered to be MOBILE GENETIC ELEMENTS. Inteins are composed of self-splicing domains and an endonuclease domain which plays a role in the spread of the intein's genomic sequence. Mini-inteins are composed of the self-splicing domains only.
| Descriptor ID |
D047668
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| MeSH Number(s) |
G02.111.570.060.440
|
| Concept/Terms |
Inteins- Inteins
- Intein
- Protein Introns
- Intervening Protein Sequence
- Intervening Protein Sequences
- Protein Sequence, Intervening
- Protein Sequences, Intervening
- Sequence, Intervening Protein
- Sequences, Intervening Protein
- Introns, Protein
- Intron, Protein
- Protein Intron
|
Below are MeSH descriptors whose meaning is more general than "Inteins".
Below are MeSH descriptors whose meaning is more specific than "Inteins".
This graph shows the total number of publications written about "Inteins" by people in this website by year, and whether "Inteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Inteins" by people in Profiles.
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Zhang B, Han Z, Kumar S, Gupta M, Su WW. Intein-ubiquitin chimeric domain for coordinated protein coexpression. J Biotechnol. 2019 Oct 10; 304:38-43.
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Han Z, Su WW. Intein-mediated assembly of tunable scaffoldins for facile synthesis of designer cellulosomes. Appl Microbiol Biotechnol. 2018 Feb; 102(3):1331-1342.
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Zhang B, Rapolu M, Kumar S, Gupta M, Liang Z, Han Z, Williams P, Su WW. Coordinated protein co-expression in plants by harnessing the synergy between an intein and a viral 2A peptide. Plant Biotechnol J. 2017 Jun; 15(6):718-728.
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Zhang B, Rapolu M, Liang Z, Han Z, Williams PG, Su WW. A dual-intein autoprocessing domain that directs synchronized protein co-expression in both prokaryotes and eukaryotes. Sci Rep. 2015 Feb 25; 5:8541.