"Aryldialkylphosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).
Descriptor ID |
D043303
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MeSH Number(s) |
D08.811.277.352.660.500
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Concept/Terms |
Aryldialkylphosphatase- Aryldialkylphosphatase
- Arylalkylphosphatase
- Homocysteine Thiolactone Hydrolase
- Hydrolase, Homocysteine Thiolactone
- Thiolactone Hydrolase, Homocysteine
- OPA Anhydrase
- Anhydrase, OPA
- Paraoxonase
- Organophosphorus Acid Anhydrase
- Acid Anhydrase, Organophosphorus
- Anhydrase, Organophosphorus Acid
- Organophosphorus Acid Anhydrolase
- Acid Anhydrolase, Organophosphorus
- Anhydrolase, Organophosphorus Acid
- Organophosphorus Acid Hydrolase
- Acid Hydrolase, Organophosphorus
- Hydrolase, Organophosphorus Acid
- Organophosphorus Hydrolase
- Hydrolase, Organophosphorus
- Aryl-dialkyl Phosphatase
- Aryl dialkyl Phosphatase
- Phosphatase, Aryl-dialkyl
- OPH Enzyme
- Enzyme, OPH
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Below are MeSH descriptors whose meaning is more general than "Aryldialkylphosphatase".
Below are MeSH descriptors whose meaning is more specific than "Aryldialkylphosphatase".
This graph shows the total number of publications written about "Aryldialkylphosphatase" by people in this website by year, and whether "Aryldialkylphosphatase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2018 | 1 | 2 | 3 |
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click here.
Below are the most recent publications written about "Aryldialkylphosphatase" by people in Profiles.
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Monero-Paredes M, Santiago E, Carrasquillo-Carrion K, Renta JY, Rogozin IB, Roche-Lima A, Duconge J. Paraoxonase-1 as a Cardiovascular Biomarker in Caribbean Hispanic Patients Treated with Clopidogrel: Abundance and Functionality. Int J Mol Sci. 2024 Oct 03; 25(19).
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Melin K, Moon JY, Qi Q, Hernandez-Suarez DF, Duconge J, Hua S, Gonzalez S, Zeng D, Kaplan RC. Prevalence of pharmacogenomic variants affecting the efficacy of clopidogrel therapy in the Hispanic Community Health Study/Study of Latinos cohort. Pharmacogenomics. 2019 01; 20(2):75-83.
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Hernandez-Suarez DF, Tomassini-Fernandini JC, Cuevas A, Rosario-Berrios AN, Nu?ez-Medina HJ, Padilla-Arroyo D, Rivera N, Liriano J, Vega-Roman RK, Renta JY, Melin K, Duconge J. Clinical Relevant Polymorphisms Affecting Clopidogrel Pharmacokinetics and Pharmacodynamics: Insights from the Puerto Rico Newborn Screening Program. Int J Environ Res Public Health. 2018 05 30; 15(6).
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Hernandez-Suarez DF, N??ez-Medina H, Scott SA, Lopez-Candales A, Wiley JM, Garcia MJ, Melin K, Nieves-Borrero K, Rodriguez-Ruiz C, Marshall L, Duconge J. Effect of cilostazol on platelet reactivity among patients with peripheral artery disease on clopidogrel therapy. Drug Metab Pers Ther. 2018 03 28; 33(1):49-55.
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Cole TB, Coburn J, Dao K, Roqu? P, Chang YC, Kalia V, Guilarte TR, Dziedzic J, Costa LG. Sex and genetic differences in the effects of acute diesel exhaust exposure on inflammation and oxidative stress in mouse brain. Toxicology. 2016 Dec 30; 374:1-9.
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Tekin Koruk S, Aksoy N, Hamidanoglu M, Karsen H, Unlu S, Bilinc H. The activity of paraoxonase and arylesterase in patients with osteomyelitis. Scand J Clin Lab Invest. 2012 Nov; 72(7):513-7.
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Lurie G, Wilkens LR, Thompson PJ, McDuffie KE, Carney ME, Terada KY, Goodman MT. Genetic polymorphisms in the Paraoxonase 1 gene and risk of ovarian epithelial carcinoma. Cancer Epidemiol Biomarkers Prev. 2008 Aug; 17(8):2070-7.