"Angiopoietin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.
| Descriptor ID |
D042702
|
| MeSH Number(s) |
D12.644.276.100.100.200 D12.776.467.100.100.200 D23.529.100.100.200
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Angiopoietin-2".
Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-2".
This graph shows the total number of publications written about "Angiopoietin-2" by people in this website by year, and whether "Angiopoietin-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Angiopoietin-2" by people in Profiles.
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Lekpor CE, Botchway F, Kusi KA, Adjei AA, Wilson MD, Stiles JK, Wilson NO. Angiogenic and angiostatic factors present in the saliva of malaria patients. Malar J. 2022 Jul 14; 21(1):220.
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Khan R, Sharma M, Kumar L, Husain SA, Sharma A. Interrelationship and expression profiling of cyclooxygenase and angiogenic factors in Indian patients with multiple myeloma. Ann Hematol. 2013 Jan; 92(1):101-9.
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Jain V, Lucchi NW, Wilson NO, Blackstock AJ, Nagpal AC, Joel PK, Singh MP, Udhayakumar V, Stiles JK, Singh N. Plasma levels of angiopoietin-1 and -2 predict cerebral malaria outcome in Central India. Malar J. 2011 Dec 23; 10:383.
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Imanishi Y, Hu B, Xiao G, Yao X, Cheng SY. Angiopoietin-2, an angiogenic regulator, promotes initial growth and survival of breast cancer metastases to the lung through the integrin-linked kinase (ILK)-AKT-B cell lymphoma 2 (Bcl-2) pathway. J Biol Chem. 2011 Aug 19; 286(33):29249-29260.
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Lucchi NW, Jain V, Wilson NO, Singh N, Udhayakumar V, Stiles JK. Potential serological biomarkers of cerebral malaria. Dis Markers. 2011; 31(6):327-35.
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Fremont RD, Koyama T, Calfee CS, Wu W, Dossett LA, Bossert FR, Mitchell D, Wickersham N, Bernard GR, Matthay MA, May AK, Ware LB. Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis. J Trauma. 2010 May; 68(5):1121-7.
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Hess AP, Hirchenhain J, Schanz A, Talbi S, Hamilton AE, Giudice LC, Kr?ssel JS. Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation. Reprod Fertil Dev. 2006; 18(5):509-16.