Cryoelectron Microscopy

"Cryoelectron Microscopy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Electron microscopy involving rapid freezing of the samples. The imaging of frozen-hydrated molecules and organelles permits the best possible resolution closest to the living state, free of chemical fixatives or stains.

Descriptor ID	D020285
MeSH Number(s)	E01.370.350.515.402.150 E05.595.402.150
Concept/Terms	Cryoelectron Microscopy Cryoelectron Microscopy Cryoelectron Microscopies Microscopies, Cryoelectron Microscopy, Cryoelectron Electron Cryomicroscopy Cryomicroscopies, Electron Cryomicroscopy, Electron Electron Cryomicroscopies Cryo-electron Microscopy Cryo electron Microscopy Cryo-electron Microscopies Microscopies, Cryo-electron Microscopy, Cryo-electron

Below are MeSH descriptors whose meaning is more general than "Cryoelectron Microscopy".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Diagnosis [E01]
Diagnostic Techniques and Procedures [E01.370]
Diagnostic Imaging [E01.370.350]
Microscopy [E01.370.350.515]
Microscopy, Electron [E01.370.350.515.402]
Cryoelectron Microscopy [E01.370.350.515.402.150]
Investigative Techniques [E05]
Microscopy [E05.595]
Microscopy, Electron [E05.595.402]
Cryoelectron Microscopy [E05.595.402.150]

Below are MeSH descriptors whose meaning is related to "Cryoelectron Microscopy".

Below are MeSH descriptors whose meaning is more specific than "Cryoelectron Microscopy".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cryoelectron Microscopy" by people in this website by year, and whether "Cryoelectron Microscopy" was a major or minor topic of these publications.

Bar chart showing 47 publications over 20 distinct years, with a maximum of 5 publications in 2009 and 2010 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2003	0	1	1
2005	1	2	3
2006	1	2	3
2007	1	1	2
2009	0	5	5
2010	1	4	5
2011	1	2	3
2012	0	1	1
2013	1	1	2
2014	1	0	1
2016	0	1	1
2017	1	0	1
2018	2	3	5
2019	0	2	2
2020	0	2	2
2022	0	2	2
2023	0	2	2
2024	2	1	3
2025	0	2	2

Below are the most recent publications written about "Cryoelectron Microscopy" by people in Profiles.

Zhang S, Yi R, An L, Liu J, Yao X, Li S, Zhang K. Structural insights into higher-order natural RNA-only multimers. Nat Struct Mol Biol. 2025 Oct; 32(10):2012-2021.

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Sato K, Uehara S, Tsugita A, Ishii M, Ishiyama S, Maejima A, Nakahara I, Nazuka M, Matsui T, Christos G, Yokoyama T, Kumagai I, Makabe K, Asano R, Tanaka Y. Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement. Cell Rep. 2025 Jul 22; 44(7):115965.

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Wang T, Li Z, Xu K, Huang W, Huang G, Zhang QC, Yan N. CryoSeek: A strategy for bioentity discovery using cryoelectron microscopy. Proc Natl Acad Sci U S A. 2024 Oct 15; 121(42):e2417046121.

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Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C. Mechanism of ?-Pro/C-degron recognition by the CRL2FEM1B ubiquitin ligase. Nat Commun. 2024 Apr 26; 15(1):3558.

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Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, Xing Z, Fan R, Zhang QC, Shi Y. Structural insights into branch site proofreading by human spliceosome. Nat Struct Mol Biol. 2024 May; 31(5):835-845.

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Hutchins GH, Noble CEM, Bunzel HA, Williams C, Dubiel P, Yadav SKN, Molinaro PM, Barringer R, Blackburn H, Hardy BJ, Parnell AE, Landau C, Race PR, Oliver TAA, Koder RL, Crump MP, Schaffitzel C, Oliveira ASF, Mulholland AJ, Anderson JLR. An expandable, modular de novo protein platform for precision redox engineering. Proc Natl Acad Sci U S A. 2023 08; 120(31):e2306046120.

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Dai M, Dong Z, Xu K, Zhang QC. CryoRes: Local Resolution Estimation of Cryo-EM Density Maps by Deep Learning. J Mol Biol. 2023 05 01; 435(9):168059.

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Budiardjo SJ, Stevens JJ, Calkins AL, Ikujuni AP, Wimalasena VK, Firlar E, Case DA, Biteen JS, Kaelber JT, Slusky JSG. Colicin E1 opens its hinge to plug TolC. Elife. 2022 02 24; 11.

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Xu D, Li Y, Yang F, Sun CR, Pan J, Wang L, Chen ZP, Fang SC, Yao X, Hou WT, Zhou CZ, Chen Y. Structure and transport mechanism of the human cholesterol transporter ABCG1. Cell Rep. 2022 01 25; 38(4):110298.

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Eriksen MS, Nikolaienko O, Hallin EI, Gr?dem S, Bustad HJ, Flydal MI, Merski I, Hosokawa T, Lascu D, Akerkar S, Cu?llar J, Chambers JJ, O'Connell R, Muruganandam G, Loris R, Touma C, Kanhema T, Hayashi Y, Stratton MM, Valpuesta JM, Kursula P, Martinez A, Bramham CR. Arc self-association and formation of virus-like capsids are mediated by an N-terminal helical coil motif. FEBS J. 2021 05; 288(9):2930-2955.

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