"P-Glycoprotein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
| Descriptor ID |
D020168
|
| MeSH Number(s) |
D12.776.157.530.100.652.500 D12.776.157.530.450.074.500.500.875.500 D12.776.395.550.020.610.610 D12.776.543.550.192.610.610 D12.776.543.585.100.610.500 D12.776.543.585.450.074.500.500.875.500
|
| Concept/Terms |
ATP-Binding Cassette, Sub-Family B, Member 1- ATP-Binding Cassette, Sub-Family B, Member 1
- CD243 Antigen
- Antigen, CD243
- P-Glycoprotein
- P Glycoprotein
- PGY-1 Protein
- PGY 1 Protein
- Multidrug Resistance Protein 1
- ABCB1 Protein
- MDR1 Protein
|
Below are MeSH descriptors whose meaning is more general than "P-Glycoprotein".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- ATP-Binding Cassette Transporters [D12.776.157.530.100]
- ATP Binding Cassette Transporter, Sub-Family B [D12.776.157.530.100.652]
- ATP-Binding Cassette, Sub-Family B, Member 1 [D12.776.157.530.100.652.500]
- Ion Pumps [D12.776.157.530.450]
- Anion Transport Proteins [D12.776.157.530.450.074]
- Organic Anion Transporters [D12.776.157.530.450.074.500]
- Organic Anion Transporters, ATP-Dependent [D12.776.157.530.450.074.500.500]
- ATP Binding Cassette Transporter, Sub-Family B [D12.776.157.530.450.074.500.500.875]
- ATP-Binding Cassette, Sub-Family B, Member 1 [D12.776.157.530.450.074.500.500.875.500]
- Glycoproteins [D12.776.395]
- Membrane Glycoproteins [D12.776.395.550]
- ATP-Binding Cassette Transporters [D12.776.395.550.020]
- ATP Binding Cassette Transporter, Sub-Family B [D12.776.395.550.020.610]
- ATP-Binding Cassette, Sub-Family B, Member 1 [D12.776.395.550.020.610.610]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- ATP-Binding Cassette Transporters [D12.776.543.550.192]
- ATP Binding Cassette Transporter, Sub-Family B [D12.776.543.550.192.610]
- ATP-Binding Cassette, Sub-Family B, Member 1 [D12.776.543.550.192.610.610]
- Membrane Transport Proteins [D12.776.543.585]
- ATP-Binding Cassette Transporters [D12.776.543.585.100]
- ATP Binding Cassette Transporter, Sub-Family B [D12.776.543.585.100.610]
- ATP-Binding Cassette, Sub-Family B, Member 1 [D12.776.543.585.100.610.500]
- Ion Pumps [D12.776.543.585.450]
- Anion Transport Proteins [D12.776.543.585.450.074]
- Organic Anion Transporters [D12.776.543.585.450.074.500]
- Organic Anion Transporters, ATP-Dependent [D12.776.543.585.450.074.500.500]
- ATP Binding Cassette Transporter, Sub-Family B [D12.776.543.585.450.074.500.500.875]
- ATP-Binding Cassette, Sub-Family B, Member 1 [D12.776.543.585.450.074.500.500.875.500]
Below are MeSH descriptors whose meaning is more specific than "P-Glycoprotein".
This graph shows the total number of publications written about "P-Glycoprotein" by people in this website by year, and whether "P-Glycoprotein" was a major or minor topic of these publications.
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Below are the most recent publications written about "P-Glycoprotein" by people in Profiles.