Linoleic Acid

"Linoleic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed)

Descriptor ID	D019787
MeSH Number(s)	D10.251.355.310.515.500 D10.251.355.343.500.500
Concept/Terms	Linoleic Acid Linoleic Acid 9,12-Octadecadienoic Acid 9,12 Octadecadienoic Acid Acid, 9,12-Octadecadienoic Linoleate Linoleate Linoleic Acid, (Z,E)-Isomer Linoleic Acid, (Z,E)-Isomer Linoleic Acid, (Z,Z)-Isomer Linoleic Acid, (Z,Z)-Isomer cis,cis-9,12-Octadecadienoic Acid Linolelaidic Acid Linolelaidic Acid trans,trans-9,12-Octadecadienoic Acid Linoleic Acid, (E,E)-Isomer 9-trans,12-trans-Octadecadienoic Acid 9 trans,12 trans Octadecadienoic Acid Linoelaidic Acid Linoleic Acid, Ammonium Salt, (Z,Z)-Isomer Linoleic Acid, Ammonium Salt, (Z,Z)-Isomer Linoleic Acid, Calcium Salt, (Z,Z)-Isomer Linoleic Acid, Calcium Salt, (Z,Z)-Isomer Linoleic Acid, Potassium Salt, (Z,Z)-Isomer Linoleic Acid, Potassium Salt, (Z,Z)-Isomer Linoleic Acid, Sodium Salt, (E,E)-Isomer Linoleic Acid, Sodium Salt, (E,E)-Isomer Linoleic Acid, Sodium Salt, (Z,Z)-Isomer Linoleic Acid, Sodium Salt, (Z,Z)-Isomer Linoelaidic Acid, (E,Z)-Isomer Linoelaidic Acid, (E,Z)-Isomer Linoleic Acid, (Z,Z)-Isomer, 14C-Labeled Linoleic Acid, (Z,Z)-Isomer, 14C-Labeled

Below are MeSH descriptors whose meaning is more general than "Linoleic Acid".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Fatty Acids, Essential [D10.251.355.310]
Linoleic Acids [D10.251.355.310.515]
Linoleic Acid [D10.251.355.310.515.500]
Fatty Acids, Omega-6 [D10.251.355.343]
Linoleic Acids [D10.251.355.343.500]
Linoleic Acid [D10.251.355.343.500.500]

Below are MeSH descriptors whose meaning is related to "Linoleic Acid".

Below are MeSH descriptors whose meaning is more specific than "Linoleic Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Linoleic Acid" by people in this website by year, and whether "Linoleic Acid" was a major or minor topic of these publications.

Bar chart showing 8 publications over 7 distinct years, with a maximum of 2 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2005	0	1	1
2011	0	1	1
2015	1	0	1
2016	1	1	2
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Linoleic Acid" by people in Profiles.

Jang S, Javadov S. Unraveling the mechanisms of cardiolipin function: The role of oxidative polymerization of unsaturated acyl chains. Redox Biol. 2023 08; 64:102774.

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Mart?nez R, Mesas C, Guzm?n A, Galisteo M, L?pez-Jurado M, Prados J, Melguizo C, Berm?dez F, Porres JM. Bioavailability and biotransformation of linolenic acid from basil seed oil as a novel source of omega-3 fatty acids tested on a rat experimental model. Food Funct. 2022 Jul 18; 13(14):7614-7628.

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Chang YW, Assari S, Prossin AR, Stertz L, McInnis MG, Evans SJ. Bipolar disorder moderates associations between linoleic acid and markers of inflammation. J Psychiatr Res. 2017 02; 85:29-36.

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Ma C, Kesarwala AH, Eggert T, Medina-Echeverz J, Kleiner DE, Jin P, Stroncek DF, Terabe M, Kapoor V, ElGindi M, Han M, Thornton AM, Zhang H, Egger M, Luo J, Felsher DW, McVicar DW, Weber A, Heikenwalder M, Greten TF. NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis. Nature. 2016 Mar 10; 531(7593):253-7.

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Evans SJ, Assari S, Harrington GJ, Chang YW, Burant CF, McInnis MG. Plasma linoleic acid partially mediates the association of bipolar disorder on self-reported mental health scales. J Psychiatr Res. 2015 Sep; 68:61-7.

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Lee S, Curb JD, Kadowaki T, Evans RW, Miura K, Takamiya T, Shin C, El-Saed A, Choo J, Fujiyoshi A, Otake T, Kadowaki S, Seto T, Masaki K, Edmundowicz D, Ueshima H, Kuller LH, Sekikawa A. Significant inverse associations of serum n-6 fatty acids with plasma plasminogen activator inhibitor-1. Br J Nutr. 2012 Feb; 107(4):567-72.

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Li Y, Zhang J, Schopfer FJ, Martynowski D, Garcia-Barrio MT, Kovach A, Suino-Powell K, Baker PR, Freeman BA, Chen YE, Xu HE. Molecular recognition of nitrated fatty acids by PPAR gamma. Nat Struct Mol Biol. 2008 Aug; 15(8):865-7.

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Kashfi K, Rigas B. Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention. Biochem Pharmacol. 2005 Oct 01; 70(7):969-86.

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Kishino S, Ogawa J, Ando A, Iwashita T, Fujita T, Kawashima H, Shimizu S. Structural analysis of conjugated linoleic acid produced by Lactobacillus plantarum, and factors affecting isomer production. Biosci Biotechnol Biochem. 2003 Jan; 67(1):179-82.

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