"Thapsigargin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.
Descriptor ID |
D019284
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MeSH Number(s) |
D02.455.426.392.368.284.500.888 D02.455.849.765.793.888
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thapsigargin".
Below are MeSH descriptors whose meaning is more specific than "Thapsigargin".
This graph shows the total number of publications written about "Thapsigargin" by people in this website by year, and whether "Thapsigargin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thapsigargin" by people in Profiles.
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Shimoda LM, Showman A, Baker JD, Lange I, Koomoa DL, Stokes AJ, Borris RP, Turner H. Differential regulation of calcium signalling pathways by components of Piper methysticum ('Awa). Phytother Res. 2015 Apr; 29(4):582-90.
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Fredericks GJ, Hoffmann FW, Rose AH, Osterheld HJ, Hess FM, Mercier F, Hoffmann PR. Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16478-83.
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Jiang CC, Lucas K, Avery-Kiejda KA, Wade M, deBock CE, Thorne RF, Allen J, Hersey P, Zhang XD. Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. Cancer Res. 2008 Aug 15; 68(16):6708-17.
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Micevych PE, Chaban V, Ogi J, Dewing P, Lu JK, Sinchak K. Estradiol stimulates progesterone synthesis in hypothalamic astrocyte cultures. Endocrinology. 2007 Feb; 148(2):782-9.
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De Mello WC, Monterrubio J. Intracellular and extracellular angiotensin II enhance the L-type calcium current in the failing heart. Hypertension. 2004 Sep; 44(3):360-4.
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Dontenwill M, Pascal G, Piletz JE, Chen M, Baldwin J, Rond? P, Dupuy L, Urosevic D, Greney H, Takeda K, Bousquet P. IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells. Cell Death Differ. 2003 Aug; 10(8):933-5.
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Opere CA, Ohia SE. Role of intracellular calcium in peroxide-induced potentiation of norepinephrine release from bovine isolated irides. Gen Pharmacol. 1998 Nov; 31(5):793-8.