Prostatic Intraepithelial Neoplasia
"Prostatic Intraepithelial Neoplasia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.
| Descriptor ID |
D019048
|
| MeSH Number(s) |
C04.557.470.200.240.500
|
| Concept/Terms |
Prostatic Intraepithelial Neoplasia- Prostatic Intraepithelial Neoplasia
- Neoplasia, Prostatic Intraepithelial
- Intraepithelial Neoplasia, Prostatic
- Prostatic Intraepithelial Neoplasias
- Prostatic Intraepithelial Neoplasms
- Intraepithelial Neoplasm, Prostatic
- Intraepithelial Neoplasms, Prostatic
- Neoplasm, Prostatic Intraepithelial
- Neoplasms, Prostatic Intraepithelial
- Prostatic Intraepithelial Neoplasm
- Intraepithelial Prostatic Neoplasia
- Intraepithelial Prostatic Neoplasias
- Neoplasia, Intraepithelial Prostatic
- Prostatic Neoplasia, Intraepithelial
|
Below are MeSH descriptors whose meaning is more general than "Prostatic Intraepithelial Neoplasia".
Below are MeSH descriptors whose meaning is more specific than "Prostatic Intraepithelial Neoplasia".
This graph shows the total number of publications written about "Prostatic Intraepithelial Neoplasia" by people in this website by year, and whether "Prostatic Intraepithelial Neoplasia" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Prostatic Intraepithelial Neoplasia" by people in Profiles.
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Messex JK, Byrd CJ, Thomas MU, Liou GY. Macrophages Cytokine Spp1 Increases Growth of Prostate Intraepithelial Neoplasia to Promote Prostate Tumor Progression. Int J Mol Sci. 2022 Apr 12; 23(8).
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Thomas MU, Messex JK, Dang T, Abdulkadir SA, Jorcyk CL, Liou GY. Macrophages expedite cell proliferation of prostate intraepithelial neoplasia through their downstream target ERK. FEBS J. 2021 03; 288(6):1871-1886.
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Devaney JM, Wang S, Funda S, Long J, Taghipour DJ, Tbaishat R, Furbert-Harris P, Ittmann M, Kwabi-Addo B. Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia. Prostate Cancer Prostatic Dis. 2013 Dec; 16(4):292-300.
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Sharma P, Knowell AE, Chinaranagari S, Komaragiri S, Nagappan P, Patel D, Havrda MC, Chaudhary J. Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN. Mol Cancer. 2013 Jun 21; 12:67.
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Ru P, Steele R, Nerurkar PV, Phillips N, Ray RB. Bitter melon extract impairs prostate cancer cell-cycle progression and delays prostatic intraepithelial neoplasia in TRAMP model. Cancer Prev Res (Phila). 2011 Dec; 4(12):2122-30.
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Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW. Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett. 2009 Sep 28; 283(1):29-35.
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Nardella C, Chen Z, Salmena L, Carracedo A, Alimonti A, Egia A, Carver B, Gerald W, Cordon-Cardo C, Pandolfi PP. Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events. Genes Dev. 2008 Aug 15; 22(16):2172-7.
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M'Koma AE, Blum DL, Norris JL, Koyama T, Billheimer D, Motley S, Ghiassi M, Ferdowsi N, Bhowmick I, Chang SS, Fowke JH, Caprioli RM, Bhowmick NA. Detection of pre-neoplastic and neoplastic prostate disease by MALDI profiling of urine. Biochem Biophys Res Commun. 2007 Feb 16; 353(3):829-34.
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Ropiquet F, Giri D, Kwabi-Addo B, Mansukhani A, Ittmann M. Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Cancer Res. 2000 Aug 01; 60(15):4245-50.