Insulin-Like Growth Factor Binding Protein 1
"Insulin-Like Growth Factor Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
| Descriptor ID |
D018970
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| MeSH Number(s) |
D12.776.157.420.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 1".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in this website by year, and whether "Insulin-Like Growth Factor Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in Profiles.
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Esemu LF, Yuosembom EK, Fang R, Rasay S, Fodjo BAY, Nguasong JT, Kidima W, Ekali GL, Chen JJ, Ndhlovu L, Bigoga JD, Taylor DW, Leke RGF, Babakhanyan A. Impact of HIV-1 infection on the IGF-1 axis and angiogenic factors in pregnant Cameroonian women receiving antiretroviral therapy. PLoS One. 2019; 14(5):e0215825.
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Merritt MA, Strickler HD, Einstein MH, Yang HP, Sherman ME, Wentzensen N, Brouwer-Visser J, Cossio MJ, Whitney KD, Yu H, Gunter MJ, Huang GS. Insulin/IGF and sex hormone axes in human endometrium and associations with endometrial cancer risk factors. Cancer Causes Control. 2016 06; 27(6):737-48.
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Verheus M, Maskarinec G, Woolcott CG, Haiman CA, Le Marchand L, Henderson BE, Cheng I, Kolonel LN. IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort. Int J Cancer. 2010 Sep 01; 127(5):1115-23.
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Khorram O, Laughlin GA, Yen SS. Endocrine and metabolic effects of long-term administration of [Nle27]growth hormone-releasing hormone-(1-29)-NH2 in age-advanced men and women. J Clin Endocrinol Metab. 1997 May; 82(5):1472-9.
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Bryant-Greenwood GD, Rutanen EM, Partanen S, Coelho TK, Yamamoto SY. Sequential appearance of relaxin, prolactin and IGFBP-1 during growth and differentiation of the human endometrium. Mol Cell Endocrinol. 1993 Sep; 95(1-2):23-9.