Lupus Coagulation Inhibitor
"Lupus Coagulation Inhibitor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiphospholipid antibody found in association with systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC;), ANTIPHOSPHOLIPID SYNDROME; and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including fetal death and spontaneous abortion, as well as a variety of hematologic and neurologic complications.
| Descriptor ID |
D016682
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| MeSH Number(s) |
D12.776.124.486.485.114.323.210.600 D12.776.124.790.651.114.323.210.600 D12.776.377.715.548.114.323.210.600 D23.113.475
|
| Concept/Terms |
Lupus Coagulation Inhibitor- Lupus Coagulation Inhibitor
- Inhibitor, Lupus Coagulation
- Coagulation Inhibitor, Lupus
- Lupus Anticoagulant
- Anticoagulant, Lupus
|
Below are MeSH descriptors whose meaning is more general than "Lupus Coagulation Inhibitor".
Below are MeSH descriptors whose meaning is more specific than "Lupus Coagulation Inhibitor".
This graph shows the total number of publications written about "Lupus Coagulation Inhibitor" by people in this website by year, and whether "Lupus Coagulation Inhibitor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lupus Coagulation Inhibitor" by people in Profiles.
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Calvo-Al?n J, Toloza SM, Fern?ndez M, Bastian HM, Fessler BJ, Roseman JM, McGwin G, Vil? LM, Reveille JD, Alarc?n GS. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA). XXV. Smoking, older age, disease activity, lupus anticoagulant, and glucocorticoid dose as risk factors for the occurrence of venous thrombosis in lupus patients. Arthritis Rheum. 2005 Jul; 52(7):2060-8.