"Aflatoxin B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.
| Descriptor ID |
D016604
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| MeSH Number(s) |
D03.383.663.283.119.075 D03.633.100.150.119.075 D23.946.587.142.075
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aflatoxin B1".
Below are MeSH descriptors whose meaning is more specific than "Aflatoxin B1".
This graph shows the total number of publications written about "Aflatoxin B1" by people in this website by year, and whether "Aflatoxin B1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aflatoxin B1" by people in Profiles.
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Karabulut S, Paytakov G, Leszczynski J. Reduction of aflatoxin B1 to aflatoxicol: a comprehensive DFT study provides clues to its toxicity. J Sci Food Agric. 2014 Dec; 94(15):3134-40.
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Jolly PE, Shuaib FM, Jiang Y, Preko P, Baidoo J, Stiles JK, Wang JS, Phillips TD, Williams JH. Association of high viral load and abnormal liver function with high aflatoxin B1-albumin adduct levels in HIV-positive Ghanaians: preliminary observations. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 Sep; 28(9):1224-34.
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Shuaib FM, Jolly PE, Ehiri JE, Jiang Y, Ellis WO, Stiles JK, Yatich NJ, Funkhouser E, Person SD, Wilson C, Williams JH. Association between anemia and aflatoxin B1 biomarker levels among pregnant women in Kumasi, Ghana. Am J Trop Med Hyg. 2010 Nov; 83(5):1077-83.
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Gyamfi MA, Aniya Y. Medicinal herb, Thonningia sanguinea protects against aflatoxin B1 acute hepatotoxicity in Fischer 344 rats. Hum Exp Toxicol. 1998 Aug; 17(8):418-23.