"Platelet Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
| Descriptor ID |
D015539
|
| MeSH Number(s) |
G09.188.390.600
|
| Concept/Terms |
Platelet Activation- Platelet Activation
- Activation, Platelet
- Activations, Platelet
- Platelet Activations
|
Below are MeSH descriptors whose meaning is more general than "Platelet Activation".
Below are MeSH descriptors whose meaning is more specific than "Platelet Activation".
This graph shows the total number of publications written about "Platelet Activation" by people in this website by year, and whether "Platelet Activation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "Platelet Activation" by people in Profiles.
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Burchell SR, Tang J, Zhang JH. Hematoma Expansion Following Intracerebral Hemorrhage: Mechanisms Targeting the Coagulation Cascade and Platelet Activation. Curr Drug Targets. 2017; 18(12):1329-1344.
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Kim K, Li J, Barazia A, Tseng A, Youn SW, Abbadessa G, Yu Y, Schwartz B, Andrews RK, Gordeuk VR, Cho J. ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease. Haematologica. 2017 02; 102(2):246-259.
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Roop RP, Naughton MJ, Van Poznak C, Schneider JG, Lammers PE, Pluard TJ, Johnson F, Eby CS, Weilbaecher KN. A randomized phase II trial investigating the effect of platelet function inhibition on circulating tumor cells in patients with metastatic breast cancer. Clin Breast Cancer. 2013 Dec; 13(6):409-15.
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Novelli EM, Kato GJ, Ragni MV, Zhang Y, Hildesheim ME, Nouraie M, Barge S, Meyer MP, Hassett AC, Gordeuk VR, Gladwin MT, Isenberg JS. Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates. Am J Hematol. 2012 Mar; 87(3):326-30.
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Gattis JL, Washington AV, Chisholm MM, Quigley L, Szyk A, McVicar DW, Lubkowski J. The structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment. J Biol Chem. 2006 May 12; 281(19):13396-13403.
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Wu KK. Novel mechanisms of aspirin pharmacologic actions: a model for studying herbal natural products. Thromb Res. 2005; 117(1-2):61-4; discussion 65-7.
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Washington AV, Schubert RL, Quigley L, Disipio T, Feltz R, Cho EH, McVicar DW. A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets. Blood. 2004 Aug 15; 104(4):1042-7.
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Halaris A, Piletz JE. Relevance of imidazoline receptors and agmatine to psychiatry: a decade of progress. Ann N Y Acad Sci. 2003 Dec; 1009:1-20.
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Taylor AJ, Bobik A, Berndt MC, Kalff V, Michaelides A, Jennings GL. Relation of local platelet glycoprotein IIb/IIIa independent activation during coronary angioplasty in acute myocardial infarction to recovery of left ventricular function. Am J Cardiol. 2003 Aug 15; 92(4):446-50.
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Piletz JE, Zhu H, Madakasira S, Pazzaglia P, Lindsay DeVane C, Goldman N, Halaris A. Elevated P-selectin on platelets in depression: response to bupropion. J Psychiatr Res. 2000 Nov-Dec; 34(6):397-404.