"Xanthine Oxidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An iron-molybdenum flavoprotein containing FLAVIN-ADENINE DINUCLEOTIDE that oxidizes hypoxanthine, some other purines and pterins, and aldehydes. Deficiency of the enzyme, an autosomal recessive trait, causes xanthinuria.
| Descriptor ID |
D014969
|
| MeSH Number(s) |
D08.811.682.047.928
|
| Concept/Terms |
Xanthine Oxidase- Xanthine Oxidase
- Oxidase, Xanthine
- Hypoxanthine Oxidase
- Oxidase, Hypoxanthine
- Purine-Xanthine Oxidase
- Oxidase, Purine-Xanthine
- Purine Xanthine Oxidase
- Hypoxanthine Dehydrogenase
- Dehydrogenase, Hypoxanthine
- Hypoxanthine-Xanthine Oxidase
- Hypoxanthine Xanthine Oxidase
- Oxidase, Hypoxanthine-Xanthine
|
Below are MeSH descriptors whose meaning is more general than "Xanthine Oxidase".
Below are MeSH descriptors whose meaning is more specific than "Xanthine Oxidase".
This graph shows the total number of publications written about "Xanthine Oxidase" by people in this website by year, and whether "Xanthine Oxidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Xanthine Oxidase" by people in Profiles.
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Butts B, Brown JA, Denney TS, Ballinger S, Lloyd SG, Oparil S, Sanders P, Merriman TR, Gaffo A, Singh J, Kelley EE, Calhoun DA, Dell'Italia LJ. Racial Differences in XO (Xanthine Oxidase) and Mitochondrial DNA Damage-Associated Molecular Patterns in Resistant Hypertension. Hypertension. 2022 04; 79(4):775-784.
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Butts B, Calhoun DA, Denney TS, Lloyd SG, Gupta H, Gaddam KK, Aban I, Oparil S, Sanders PW, Patel R, Collawn JF, Dell'Italia LJ. Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertension. Free Radic Biol Med. 2019 04; 134:343-349.
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Om?b?w?l? TO, Oyagbemi AA, Alaba BA, Ola-Davies OE, Adejumobi OA, Asenuga ER, Ajibade TO, Adedapo AA, Yakubu MA. Ameliorative effect of Azadirachta indica on sodium fluoride-induced hypertension through improvement of antioxidant defence system and upregulation of extracellular signal regulated kinase 1/2 signaling. J Basic Clin Physiol Pharmacol. 2018 Mar 28; 29(2):155-164.
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Givertz MM, Anstrom KJ, Redfield MM, Deswal A, Haddad H, Butler J, Tang WH, Dunlap ME, LeWinter MM, Mann DL, Felker GM, O'Connor CM, Goldsmith SR, Ofili EO, Saltzberg MT, Margulies KB, Cappola TP, Konstam MA, Semigran MJ, McNulty SE, Lee KL, Shah MR, Hernandez AF. Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study. Circulation. 2015 May 19; 131(20):1763-71.
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Yousefipour Z, Zhang C, Monfareed M, Walker J, Newaz M. Acrolein-induced oxidative stress in NAD(P)H Oxidase Subunit gp91phox knock-out mice and its modulation of NF?B and CD36. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):118-31.
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Newaz MA, Yousefipour Z, Oyekan A. Oxidative stress-associated vascular aging is xanthine oxidase-dependent but not NAD(P)H oxidase-dependent. J Cardiovasc Pharmacol. 2006 Sep; 48(3):88-94.
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Davila HH, Magee TR, Vernet D, Rajfer J, Gonzalez-Cadavid NF. Gene transfer of inducible nitric oxide synthase complementary DNA regresses the fibrotic plaque in an animal model of Peyronie's disease. Biol Reprod. 2004 Nov; 71(5):1568-77.