"Reserpine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
| Descriptor ID |
D012110
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| MeSH Number(s) |
D03.132.436.681.933.500 D03.633.100.473.402.681.933.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Reserpine".
Below are MeSH descriptors whose meaning is more specific than "Reserpine".
This graph shows the total number of publications written about "Reserpine" by people in this website by year, and whether "Reserpine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Reserpine" by people in Profiles.
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Siddiqui M, Bhatt H, Judd EK, Oparil S, Calhoun DA. Reserpine Substantially Lowers Blood Pressure in Patients With Refractory Hypertension: A Proof-of-Concept Study. Am J Hypertens. 2020 08 04; 33(8):741-747.
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Wang Z, Ferdousy F, Lawal H, Huang Z, Daigle JG, Izevbaye I, Doherty O, Thomas J, Stathakis DG, O'Donnell JM. Catecholamines up integrates dopamine synthesis and synaptic trafficking. J Neurochem. 2011 Dec; 119(6):1294-305.