"Prazosin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
Descriptor ID |
D011224
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MeSH Number(s) |
D03.633.100.786.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Prazosin".
Below are MeSH descriptors whose meaning is more specific than "Prazosin".
This graph shows the total number of publications written about "Prazosin" by people in this website by year, and whether "Prazosin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
2006 | 0 | 1 | 1 |
2007 | 1 | 1 | 2 |
2014 | 0 | 2 | 2 |
2015 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Prazosin" by people in Profiles.
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Raskind MA, Peskind ER, Chow B, Harris C, Davis-Karim A, Holmes HA, Hart KL, McFall M, Mellman TA, Reist C, Romesser J, Rosenheck R, Shih MC, Stein MB, Swift R, Gleason T, Lu Y, Huang GD. Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans. N Engl J Med. 2018 02 08; 378(6):507-517.
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Brownlow JA, Harb GC, Ross RJ. Treatment of Sleep Disturbances in Post-Traumatic Stress Disorder: A Review of the Literature. Curr Psychiatry Rep. 2015 Jun; 17(6):41.
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Vel?squez-Mart?nez MC, V?zquez-Torres R, Rojas LV, Sanabria P, Jim?nez-Rivera CA. Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons. Neuropharmacology. 2015 Jan; 88:110-21.
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Kuang YH, Patel JP, Sodani K, Wu CP, Liao LQ, Patel A, Tiwari AK, Dai CL, Chen X, Fu LW, Ambudkar SV, Korlipara VL, Chen ZS. OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance. Biochem Pharmacol. 2012 Sep 15; 84(6):766-74.
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Shi Z, Tiwari AK, Shukla S, Robey RW, Singh S, Kim IW, Bates SE, Peng X, Abraham I, Ambudkar SV, Talele TT, Fu LW, Chen ZS. Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance. Cancer Res. 2011 Apr 15; 71(8):3029-41.
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Taylor FB, Martin P, Thompson C, Williams J, Mellman TA, Gross C, Peskind ER, Raskind MA. Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: a placebo-controlled study. Biol Psychiatry. 2008 Mar 15; 63(6):629-32.
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Arencibia-Albite F, Paladini C, Williams JT, Jim?nez-Rivera CA. Noradrenergic modulation of the hyperpolarization-activated cation current (Ih) in dopamine neurons of the ventral tegmental area. Neuroscience. 2007 Oct 26; 149(2):303-14.
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Jim?nez-Rivera CA, Feliu-Mojer M, V?zquez-Torres R. Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization. Ann N Y Acad Sci. 2006 Aug; 1074:390-402.
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Dehkordi O, Dennis GC, Millis RM, Trouth CO. Cardiorespiratory effects of cocaine and procaine at the ventral brainstem. Neurotoxicology. 1996; 17(2):387-95.
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Clark JT, Gist RS, Kalra SP, Kalra PS. Alpha 2-adrenoceptor blockade attenuates feeding behavior induced by neuropeptide Y and epinephrine. Physiol Behav. 1988; 43(4):417-22.