Adenomatous Polyposis Coli

"Adenomatous Polyposis Coli" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Descriptor ID	D011125
MeSH Number(s)	C04.557.470.035.215.100 C04.588.274.476.411.307.089 C04.700.100 C06.301.371.411.307.090 C06.405.249.411.307.090 C06.405.469.158.356.090 C06.405.469.491.307.090 C06.405.469.578.249 C16.320.700.100
Concept/Terms	Adenomatous Polyposis Coli Adenomatous Polyposis Coli Adenomatous Polyposis Colus Coli, Adenomatous Polyposis Colus, Adenomatous Polyposis Polyposis Coli, Adenomatous Polyposis Colus, Adenomatous Polyposis Syndrome, Familial Familial Polyposis Syndromes Familial Adenomatous Polyposis Coli Adenomatous Polyposis Coli, Familial Adenomatous Polyposis of the Colon Familial Adenomatous Polyposis Adenomatous Polyposes, Familial Adenomatous Polyposis, Familial Familial Adenomatous Polyposes Polyposes, Familial Adenomatous Polyposis, Familial Adenomatous Familial Polyposis Coli Familial Adenomatous Polyposis of the Colon Familial Multiple Polyposi Familial Multiple Polyposus Multiple Polyposi, Familial Multiple Polyposus, Familial Polyposi, Familial Multiple Polyposus, Familial Multiple Familial Polyposis of the Colon Hereditary Polyposis Coli Coli, Hereditary Polyposis Colus, Hereditary Polyposis Hereditary Polyposis Colus Polyposis Coli, Hereditary Polyposis Colus, Hereditary Familial Multiple Polyposis Familial Multiple Polyposes Multiple Polyposes, Familial Multiple Polyposis, Familial Polyposes, Familial Multiple Polyposis, Familial Multiple Familial Multiple Polyposis Syndrome Familial Polyposis Syndrome Myh-Associated Polyposis Myh Associated Polyposis Myh-Associated Polyposes Polyposes, Myh-Associated Polyposis, Myh-Associated Polyposis Coli Coli, Polyposis Colus, Polyposis Polyposis Colus Polyposis Coli, Familial Coli, Familial Polyposis Colus, Familial Polyposis Familial Polyposis Colus Polyposis Colus, Familial Familial Intestinal Polyposis Familial Intestinal Polyposis Familial Intestinal Polyposes Intestinal Polyposes, Familial Intestinal Polyposis, Familial Polyposis, Adenomatous Intestinal Polyposis, Adenomatous Intestinal Adenomatous Intestinal Polyposes Adenomatous Intestinal Polyposis Intestinal Polyposis, Adenomatous

Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Glandular and Epithelial [C04.557.470]
Adenoma [C04.557.470.035]
Adenomatous Polyps [C04.557.470.035.215]
Adenomatous Polyposis Coli [C04.557.470.035.215.100]
Neoplasms by Site [C04.588]
Digestive System Neoplasms [C04.588.274]
Gastrointestinal Neoplasms [C04.588.274.476]
Intestinal Neoplasms [C04.588.274.476.411]
Colorectal Neoplasms [C04.588.274.476.411.307]
Adenomatous Polyposis Coli [C04.588.274.476.411.307.089]
Neoplastic Syndromes, Hereditary [C04.700]
Adenomatous Polyposis Coli [C04.700.100]
Digestive System Diseases [C06]
Digestive System Neoplasms [C06.301]
Gastrointestinal Neoplasms [C06.301.371]
Intestinal Neoplasms [C06.301.371.411]
Colorectal Neoplasms [C06.301.371.411.307]
Adenomatous Polyposis Coli [C06.301.371.411.307.090]
Gastrointestinal Diseases [C06.405]
Gastrointestinal Neoplasms [C06.405.249]
Intestinal Neoplasms [C06.405.249.411]
Colorectal Neoplasms [C06.405.249.411.307]
Adenomatous Polyposis Coli [C06.405.249.411.307.090]
Intestinal Diseases [C06.405.469]
Colonic Diseases [C06.405.469.158]
Colorectal Neoplasms [C06.405.469.158.356]
Adenomatous Polyposis Coli [C06.405.469.158.356.090]
Intestinal Neoplasms [C06.405.469.491]
Colorectal Neoplasms [C06.405.469.491.307]
Adenomatous Polyposis Coli [C06.405.469.491.307.090]
Intestinal Polyposis [C06.405.469.578]
Adenomatous Polyposis Coli [C06.405.469.578.249]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Neoplastic Syndromes, Hereditary [C16.320.700]
Adenomatous Polyposis Coli [C16.320.700.100]

Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli".

Adenomatous Polyposis Coli
Gardner Syndrome

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adenomatous Polyposis Coli" by people in this website by year, and whether "Adenomatous Polyposis Coli" was a major or minor topic of these publications.

Bar chart showing 27 publications over 13 distinct years, with a maximum of 4 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	1	2
2002	1	2	3
2003	1	1	2
2004	2	1	3
2005	2	0	2
2006	2	0	2
2007	1	1	2
2008	0	1	1
2011	1	0	1
2013	1	0	1
2016	2	0	2
2018	4	0	4
2022	2	0	2

Below are the most recent publications written about "Adenomatous Polyposis Coli" by people in Profiles.

Ballester V, Cruz-Correa M. Approach to Familial Predisposition to Colorectal Cancer. Gastroenterol Clin North Am. 2022 09; 51(3):593-607.

View in: PubMed
Samadder NJ, Foster N, McMurray RP, Burke CA, Stoffel E, Kanth P, Das R, Cruz-Correa M, Vilar E, Mankaney G, Buttar N, Thirumurthi S, Turgeon DK, Sossenheimer M, Westover M, Richmond E, Umar A, Della'Zanna G, Rodriguez LM, Szabo E, Zahrieh D, Limburg PJ. Phase II trial of weekly erlotinib dosing to reduce duodenal polyp burden associated with familial adenomatous polyposis. Gut. 2023 02; 72(2):256-263.

View in: PubMed
Cruz-Correa M, Gonzalez-Pons MDM. Reassessing colectomy in young patients with familial adenomatous polyposis. Gastrointest Endosc. 2018 10; 88(4):734-736.

View in: PubMed
Cruz-Correa M, Hylind LM, Marrero JH, Zahurak ML, Murray-Stewart T, Casero RA, Montgomery EA, Iacobuzio-Donahue C, Brosens LA, Offerhaus GJ, Umar A, Rodriguez LM, Giardiello FM. Efficacy and Safety of Curcumin in Treatment of Intestinal Adenomas in Patients With Familial Adenomatous Polyposis. Gastroenterology. 2018 09; 155(3):668-673.

View in: PubMed
Samadder NJ, Kuwada SK, Boucher KM, Byrne K, Kanth P, Samowitz W, Jones D, Tavtigian SV, Westover M, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Burt RW, Neklason DW. Association of Sulindac and Erlotinib vs Placebo With Colorectal Neoplasia in Familial Adenomatous Polyposis: Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2018 05 01; 4(5):671-677.

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Marqu?s-Lespier JM, Soto-Salgado M, Gonz?lez-Pons M, M?ndez V, Freyre K, Beltr?n C, Pericchi LR, Cruz-Correa M. Prevalence of Synchronous Oligopolyposis in Incident Colorectal Cancer: A Population-Based Study. P R Health Sci J. 2018 03; 37(1):39-45.

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Casellas-Cabrera N, D?az-Algorri Y, Carlo-Ch?vere VJ, Gonz?lez-Pons M, Rodr?guez-Ma??n N, P?rez-Mayoral J, Bertr?n-Rodr?guez C, Soto-Salgado M, Giardiello FM, Rodr?guez-Quilichini S, Cruz-Correa M. Risk of thyroid cancer among Caribbean Hispanic patients with familial adenomatous polyposis. Fam Cancer. 2016 Apr; 15(2):267-74.

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Samadder NJ, Neklason DW, Boucher KM, Byrne KR, Kanth P, Samowitz W, Jones D, Tavtigian SV, Done MW, Berry T, Jasperson K, Pappas L, Smith L, Sample D, Davis R, Topham MK, Lynch P, Strait E, McKinnon W, Burt RW, Kuwada SK. Effect of Sulindac and Erlotinib vs Placebo on Duodenal Neoplasia in Familial Adenomatous Polyposis: A Randomized Clinical Trial. JAMA. 2016 Mar 22-29; 315(12):1266-75.

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Cruz-Correa M, Diaz-Algorri Y, Mendez V, Vazquez PJ, Lozada ME, Freyre K, Lathroum L, Gonzalez-Pons M, Hernandez-Marrero J, Giardiello F, Rodriguez-Quilichini S. Clinical characterization and mutation spectrum in Hispanic families with adenomatous polyposis syndromes. Fam Cancer. 2013 Sep; 12(3):555-62.

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Edelstein DL, Giardiello FM, Basiri A, Hylind LM, Romans K, Axilbund JE, Cruz-Correa M, Ramella-Roman JC. A new phenotypic manifestation of familial adenomatous polyposis. Fam Cancer. 2011 Jun; 10(2):309-13.

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