"Methylmalonic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
| Descriptor ID |
D008764
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| MeSH Number(s) |
D02.241.081.337.540.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methylmalonic Acid".
Below are MeSH descriptors whose meaning is more specific than "Methylmalonic Acid".
This graph shows the total number of publications written about "Methylmalonic Acid" by people in this website by year, and whether "Methylmalonic Acid" was a major or minor topic of these publications.
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Below are the most recent publications written about "Methylmalonic Acid" by people in Profiles.
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Ajayi OI, Bwayo-Weaver S, Chirla S, Serlemitsos-Day M, Daniel M, Nouraie M, Edwards K, Castro O, Lombardo F, Gordeuk VR. Cobalamin status in sickle cell disease. Int J Lab Hematol. 2013 Feb; 35(1):31-7.
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Guerra-Moreno J, Barrios N, Santiago-Borrero PJ. Severe neutropenia in an infant with methylmalonic acidemia. Bol Asoc Med P R. 2003 Jan-Feb; 95(1):17-20.
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Arinze IJ, Waters D, Donaldson MK. Effect of methylamalonic acid on gluconeogenesis in isolated rat and guinea-pig hepatocytes. Biochem J. 1979 Dec 15; 184(3):717-9.