"Melitten" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Basic polypeptide from the venom of the honey bee (Apis mellifera). It contains 26 amino acids, has cytolytic properties, causes contracture of muscle, releases histamine, and disrupts surface tension, probably due to lysis of cell and mitochondrial membranes.
| Descriptor ID |
D008555
|
| MeSH Number(s) |
D12.644.050.550 D12.776.543.695.054.550 D20.888.065.115.580 D23.946.833.065.115.580
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Melitten".
Below are MeSH descriptors whose meaning is more specific than "Melitten".
This graph shows the total number of publications written about "Melitten" by people in this website by year, and whether "Melitten" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Melitten" by people in Profiles.
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Sepehri A, PeBenito L, Pino-Angeles A, Lazaridis T. What Makes a Good Pore Former: A Study of Synthetic Melittin Derivatives. Biophys J. 2020 04 21; 118(8):1901-1913.
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Pino-Angeles A, Lazaridis T. Effects of Peptide Charge, Orientation, and Concentration on Melittin Transmembrane Pores. Biophys J. 2018 06 19; 114(12):2865-2874.
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Leveritt JM, Pino-Angeles A, Lazaridis T. The structure of a melittin-stabilized pore. Biophys J. 2015 May 19; 108(10):2424-2426.
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He Y, Prieto L, Lazaridis T. Modeling peptide binding to anionic membrane pores. J Comput Chem. 2013 Jun 30; 34(17):1463-75.
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Zhan H, Lazaridis T. Inclusion of lateral pressure/curvature stress effects in implicit membrane models. Biophys J. 2013 Feb 05; 104(3):643-54.
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Mihajlovic M, Lazaridis T. Charge distribution and imperfect amphipathicity affect pore formation by antimicrobial peptides. Biochim Biophys Acta. 2012 May; 1818(5):1274-83.
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Mihajlovic M, Lazaridis T. Antimicrobial peptides in toroidal and cylindrical pores. Biochim Biophys Acta. 2010 Aug; 1798(8):1485-93.
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Mihajlovic M, Lazaridis T. Antimicrobial peptides bind more strongly to membrane pores. Biochim Biophys Acta. 2010 Aug; 1798(8):1494-502.
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Lazaridis T. Implicit solvent simulations of peptide interactions with anionic lipid membranes. Proteins. 2005 Feb 15; 58(3):518-27.
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Lazaridis T. Effective energy function for proteins in lipid membranes. Proteins. 2003 Aug 01; 52(2):176-92.