Hydroxymethylglutaryl-CoA Synthase
"Hydroxymethylglutaryl-CoA Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the synthesis of hydroxymethylglutaryl-CoA from acetyl-CoA and acetoacetyl-CoA. This is a key enzyme in steroid biosynthesis. This enzyme was formerly listed as EC 4.1.3.5.
| Descriptor ID |
D006904
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| MeSH Number(s) |
D08.811.913.050.612
|
| Concept/Terms |
Hydroxymethylglutaryl-CoA Synthase- Hydroxymethylglutaryl-CoA Synthase
- Hydroxymethylglutaryl CoA Synthase
- Synthase, Hydroxymethylglutaryl-CoA
- 3-hydroxy-3-methylglutaryl-coenzyme A synthase
- HMG-CoA synthase
|
Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl-CoA Synthase".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl-CoA Synthase".
This graph shows the total number of publications written about "Hydroxymethylglutaryl-CoA Synthase" by people in this website by year, and whether "Hydroxymethylglutaryl-CoA Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hydroxymethylglutaryl-CoA Synthase" by people in Profiles.
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Hernandez JA, Castro VL, Reyes-Nava N, Montes LP, Quintana AM. Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development. Blood Adv. 2019 04 23; 3(8):1244-1254.
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Quintana AM, Hernandez JA, Gonzalez CG. Functional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development. PLoS One. 2017; 12(7):e0180856.
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Hu LT, Zhu BL, Lai YJ, Long Y, Zha JS, Hu XT, Zhang JH, Chen GJ. HMGCS2 promotes autophagic degradation of the amyloid-? precursor protein through ketone body-mediated mechanisms. Biochem Biophys Res Commun. 2017 04 29; 486(2):492-498.