Fetal Hemoglobin

"Fetal Hemoglobin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The major component of hemoglobin in the fetus. This HEMOGLOBIN has two alpha and two gamma polypeptide subunits in comparison to normal adult hemoglobin, which has two alpha and two beta polypeptide subunits. Fetal hemoglobin concentrations can be elevated (usually above 0.5%) in children and adults affected by LEUKEMIA and several types of ANEMIA.

Descriptor ID	D005319
MeSH Number(s)	D12.776.124.400.303 D12.776.422.316.762.320
Concept/Terms	Fetal Hemoglobin Fetal Hemoglobin Hemoglobin, Fetal Hemoglobin F

Below are MeSH descriptors whose meaning is more general than "Fetal Hemoglobin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Hemoglobins [D12.776.124.400]
Fetal Hemoglobin [D12.776.124.400.303]
Hemeproteins [D12.776.422]
Globins [D12.776.422.316]
Hemoglobins [D12.776.422.316.762]
Fetal Hemoglobin [D12.776.422.316.762.320]

Below are MeSH descriptors whose meaning is related to "Fetal Hemoglobin".

Below are MeSH descriptors whose meaning is more specific than "Fetal Hemoglobin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fetal Hemoglobin" by people in this website by year, and whether "Fetal Hemoglobin" was a major or minor topic of these publications.

Bar chart showing 10 publications over 9 distinct years, with a maximum of 2 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2000	1	0	1
2003	1	0	1
2008	1	0	1
2009	1	0	1
2013	1	0	1
2014	1	0	1
2015	0	2	2
2017	1	0	1

Below are the most recent publications written about "Fetal Hemoglobin" by people in Profiles.

Han J, Saraf SL, Molokie RE, Gordeuk VR. Use of metformin in patients with sickle cell disease. Am J Hematol. 2019 01; 94(1):E13-E15.

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Raslan R, Shah BN, Zhang X, Kanias T, Han J, Machado RF, Gladwin MT, Gordeuk VR, Saraf SL. Hemolysis and hemolysis-related complications in females vs. males with sickle cell disease. Am J Hematol. 2018 11; 93(11):E376-E380.

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Darbari DS, Vaughan KJ, Roskom K, Seamon C, Diaw L, Quinn M, Conrey A, Schechter AN, Haythornthwaite JA, Waclawiw MA, Wallen GR, Belfer I, Taylor JG. Central sensitization associated with low fetal hemoglobin levels in adults with sickle cell anemia. Scand J Pain. 2017 10; 17:279-286.

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Molokie R, Lavelle D, Gowhari M, Pacini M, Krauz L, Hassan J, Ibanez V, Ruiz MA, Ng KP, Woost P, Radivoyevitch T, Pacelli D, Fada S, Rump M, Hsieh M, Tisdale JF, Jacobberger J, Phelps M, Engel JD, Saraf S, Hsu LL, Gordeuk V, DeSimone J, Saunthararajah Y. Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study. PLoS Med. 2017 Sep; 14(9):e1002382.

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Fitzhugh CD, Hsieh MM, Allen D, Coles WA, Seamon C, Ring M, Zhao X, Minniti CP, Rodgers GP, Schechter AN, Tisdale JF, Taylor JG. Hydroxyurea-Increased Fetal Hemoglobin Is Associated with Less Organ Damage and Longer Survival in Adults with Sickle Cell Anemia. PLoS One. 2015; 10(11):e0141706.

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Darbari DS, Hampson JP, Ichesco E, Kadom N, Vezina G, Evangelou I, Clauw DJ, Taylor Vi JG, Harris RE. Frequency of Hospitalizations for Pain and Association With Altered Brain Network Connectivity in Sickle Cell Disease. J Pain. 2015 Nov; 16(11):1077-86.

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Griffin PJ, Sebastiani P, Edward H, Baldwin CT, Gladwin MT, Gordeuk VR, Chui DH, Steinberg MH. The genetics of hemoglobin A2 regulation in sickle cell anemia. Am J Hematol. 2014 Nov; 89(11):1019-23.

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Milton JN, Gordeuk VR, Taylor JG, Gladwin MT, Steinberg MH, Sebastiani P. Prediction of fetal hemoglobin in sickle cell anemia using an ensemble of genetic risk prediction models. Circ Cardiovasc Genet. 2014 Apr; 7(2):110-5.

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Saraf SL, Molokie RE, Nouraie M, Sable CA, Luchtman-Jones L, Ensing GJ, Campbell AD, Rana SR, Niu XM, Machado RF, Gladwin MT, Gordeuk VR. Differences in the clinical and genotypic presentation of sickle cell disease around the world. Paediatr Respir Rev. 2014 Mar; 15(1):4-12.

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Salomon-Andonie J, Miasnikova G, Sergueeva A, Polyakova LA, Niu X, Nekhai S, Gordeuk VR. Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood. Blood. 2013 Oct 24; 122(17):3088-9.

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