Calcitriol

"Calcitriol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.

Descriptor ID	D002117
MeSH Number(s)	D04.210.500.247.222.159.478.387.300 D04.210.500.247.808.146.478.387.300 D04.210.500.812.768.196.478.387.300 D10.570.938.146.478.387.300
Concept/Terms	Calcitriol Calcitriol 1 alpha,25-Dihydroxyvitamin D3 1 alpha,25 Dihydroxyvitamin D3 D3, 1 alpha,25-Dihydroxyvitamin alpha,25-Dihydroxyvitamin D3, 1 1,25-Dihydroxyvitamin D3 1,25 Dihydroxyvitamin D3 D3, 1,25-Dihydroxyvitamin 1 alpha,25-Dihydroxycholecalciferol 1 alpha,25 Dihydroxycholecalciferol 1,25-Dihydroxycholecalciferol 1,25 Dihydroxycholecalciferol Bocatriol Bocatriol Calcijex Calcijex Calcitriol KyraMed Calcitriol KyraMed KyraMed, Calcitriol Calcitriol-Nefro Calcitriol-Nefro Calcitriol Nefro Decostriol Decostriol MC1288 MC1288 MC-1288 MC 1288 Osteotriol Osteotriol Renatriol Renatriol Rocaltrol Rocaltrol Silkis Silkis Sitriol Sitriol Soltriol Soltriol Tirocal Tirocal 20-epi-1alpha,25-dihydroxycholecaliferol 20-epi-1alpha,25-dihydroxycholecaliferol 20 epi 1alpha,25 dihydroxycholecaliferol 1,25-dihydroxy-20-epi-Vitamin D3 1,25 dihydroxy 20 epi Vitamin D3 D3, 1,25-dihydroxy-20-epi-Vitamin 1,25(OH)2-20epi-D3 1 alpha, 25-dihydroxy-20-epi-Vitamin D3 1 alpha, 25 dihydroxy 20 epi Vitamin D3

Below are MeSH descriptors whose meaning is more general than "Calcitriol".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Fused-Ring Compounds [D04.210]
Steroids [D04.210.500]
Cholestanes [D04.210.500.247]
Cholestenes [D04.210.500.247.222]
Cholecalciferol [D04.210.500.247.222.159]
Hydroxycholecalciferols [D04.210.500.247.222.159.478]
Dihydroxycholecalciferols [D04.210.500.247.222.159.478.387]
Calcitriol [D04.210.500.247.222.159.478.387.300]
Sterols [D04.210.500.247.808]
Cholecalciferol [D04.210.500.247.808.146]
Hydroxycholecalciferols [D04.210.500.247.808.146.478]
Dihydroxycholecalciferols [D04.210.500.247.808.146.478.387]
Calcitriol [D04.210.500.247.808.146.478.387.300]
Secosteroids [D04.210.500.812]
Vitamin D [D04.210.500.812.768]
Cholecalciferol [D04.210.500.812.768.196]
Hydroxycholecalciferols [D04.210.500.812.768.196.478]
Dihydroxycholecalciferols [D04.210.500.812.768.196.478.387]
Calcitriol [D04.210.500.812.768.196.478.387.300]
Lipids [D10]
Membrane Lipids [D10.570]
Sterols [D10.570.938]
Cholecalciferol [D10.570.938.146]
Hydroxycholecalciferols [D10.570.938.146.478]
Dihydroxycholecalciferols [D10.570.938.146.478.387]
Calcitriol [D10.570.938.146.478.387.300]

Below are MeSH descriptors whose meaning is related to "Calcitriol".

Below are MeSH descriptors whose meaning is more specific than "Calcitriol".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Calcitriol" by people in this website by year, and whether "Calcitriol" was a major or minor topic of these publications.

Bar chart showing 16 publications over 11 distinct years, with a maximum of 3 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2000	1	0	1
2003	1	0	1
2004	1	0	1
2005	2	1	3
2010	1	0	1
2011	2	0	2
2012	2	0	2
2015	1	0	1
2017	1	0	1
2018	0	2	2

Below are the most recent publications written about "Calcitriol" by people in Profiles.

Dai Q, Zhu X, Manson JE, Song Y, Li X, Franke AA, Costello RB, Rosanoff A, Nian H, Fan L, Murff H, Ness RM, Seidner DL, Yu C, Shrubsole MJ. Magnesium status and supplementation influence vitamin D status and metabolism: results from a randomized trial. Am J Clin Nutr. 2018 12 01; 108(6):1249-1258.

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Alsafran S, Sherman SK, Dahdaleh FS, Ruhle B, Mercier F, Kaplan EL, Angelos P, Grogan RH. Preoperative calcitriol reduces postoperative intravenous calcium requirements and length of stay in parathyroidectomy for renal-origin hyperparathyroidism. Surgery. 2019 01; 165(1):151-157.

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Mishra A, Ayasolla K, Kumar V, Lan X, Vashistha H, Aslam R, Hussain A, Chowdhary S, Marashi Shoshtari S, Paliwal N, Popik W, Saleem MA, Malhotra A, Meggs LG, Skorecki K, Singhal PC. Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu. Am J Physiol Renal Physiol. 2018 05 01; 314(5):F832-F843.

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Richards Z, Batai K, Farhat R, Shah E, Makowski A, Gann PH, Kittles R, Nonn L. Prostatic compensation of the vitamin D axis in African American men. JCI Insight. 2017 01 26; 2(2):e91054.

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Kim IM, Norris KC, Artaza JN. Vitamin D and Cardiac Differentiation. Vitam Horm. 2016; 100:299-320.

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He Q, Ananaba GA, Patrickson J, Pitts S, Yi Y, Yan F, Eko FO, Lyn D, Black CM, Igietseme JU, Thierry-Palmer M. Chlamydial infection in vitamin D receptor knockout mice is more intense and prolonged than in wild-type mice. J Steroid Biochem Mol Biol. 2013 May; 135:7-14.

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Garcia LA, Ferrini MG, Norris KC, Artaza JN. 1,25(OH)(2)vitamin D(3) enhances myogenic differentiation by modulating the expression of key angiogenic growth factors and angiogenic inhibitors in C(2)C(12) skeletal muscle cells. J Steroid Biochem Mol Biol. 2013 Jan; 133:1-11.

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Halder SK, Sharan C, Al-Hendy A. 1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model. Biol Reprod. 2012 Apr; 86(4):116.

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Garcia LA, King KK, Ferrini MG, Norris KC, Artaza JN. 1,25(OH)2vitamin D3 stimulates myogenic differentiation by inhibiting cell proliferation and modulating the expression of promyogenic growth factors and myostatin in C2C12 skeletal muscle cells. Endocrinology. 2011 Aug; 152(8):2976-86.

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Halder SK, Goodwin JS, Al-Hendy A. 1,25-Dihydroxyvitamin D3 reduces TGF-beta3-induced fibrosis-related gene expression in human uterine leiomyoma cells. J Clin Endocrinol Metab. 2011 Apr; 96(4):E754-62.

View in: PubMed

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