Androgen Antagonists

"Androgen Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds which inhibit or antagonize the biosynthesis or actions of androgens.

Descriptor ID	D000726
MeSH Number(s)	D06.347.065 D27.505.696.399.450.065
Concept/Terms	Androgen Antagonists Androgen Antagonists Antagonists, Androgen Antiandrogens Anti-Androgen Effect Anti-Androgen Effect Anti Androgen Effect Effect, Anti-Androgen Antiandrogen Effect Effect, Antiandrogen Antiandrogen Effects Effects, Antiandrogen Anti-Androgen Effects Anti Androgen Effects Effects, Anti-Androgen

Below are MeSH descriptors whose meaning is more general than "Androgen Antagonists".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormone Antagonists [D06.347]
Androgen Antagonists [D06.347.065]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Hormones, Hormone Substitutes, and Hormone Antagonists [D27.505.696.399]
Hormone Antagonists [D27.505.696.399.450]
Androgen Antagonists [D27.505.696.399.450.065]

Below are MeSH descriptors whose meaning is related to "Androgen Antagonists".

Below are MeSH descriptors whose meaning is more specific than "Androgen Antagonists".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Androgen Antagonists" by people in this website by year, and whether "Androgen Antagonists" was a major or minor topic of these publications.

Bar chart showing 16 publications over 13 distinct years, with a maximum of 3 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2001	0	1	1
2003	0	1	1
2006	0	1	1
2008	1	0	1
2011	0	1	1
2014	1	2	3
2015	1	0	1
2016	0	1	1
2017	1	0	1
2018	1	0	1
2022	0	2	2
2023	0	1	1

Below are the most recent publications written about "Androgen Antagonists" by people in Profiles.

Gaynor AM, Flaherty KR, Root JC, Salas-Ramirez KY, Scott JM, Nelson CJ. Exercise Associated with Cognitive Function in Older Men with Prostate Cancer Undergoing Androgen Deprivation Therapy. Int J Behav Med. 2023 Dec; 30(6):924-929.

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Andrews JR, Ahmed ME, Sharma V, Britton C, Stish B, Phillips R, Kendi AT, Joshi VB, Sood A, Tollefson MK, Boorjian SA, Karnes RJ, Kwon ED. Metastasis-directed Therapy Without Androgen Deprivation Therapy in Solitary Oligorecurrent Prostate Cancer. J Urol. 2022 12; 208(6):1240-1249.

View in: PubMed
Sood A, Zhang LT, Keeley J, Butaney M, Stricker M, Andrews JR, Grauer R, Peabody JO, Rogers CG, Menon M, Abdollah F. Optimizing anti-androgen treatment use among men with pathologic lymph-node positive prostate cancer treated with radical prostatectomy: the importance of postoperative PSA kinetics. Prostate Cancer Prostatic Dis. 2024 Mar; 27(1):58-64.

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George A, Raji I, Cinar B, Kucuk O, Oyelere AK. Design, synthesis, and evaluation of the antiproliferative activity of hydantoin-derived antiandrogen-genistein conjugates. Bioorg Med Chem. 2018 05 01; 26(8):1481-1487.

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Hamilton N, Austin D, M?rquez-Garb?n D, Sanchez R, Chau B, Foos K, Wu Y, Vadgama J, Pietras R. Receptors for Insulin-Like Growth Factor-2 and Androgens as Therapeutic Targets in Triple-Negative Breast Cancer. Int J Mol Sci. 2017 Nov 02; 18(11).

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Khurana N, Talwar S, Chandra PK, Sharma P, Abdel-Mageed AB, Mondal D, Sikka SC. Sulforaphane increases the efficacy of anti-androgens by rapidly decreasing androgen receptor levels in prostate cancer cells. Int J Oncol. 2016 Oct; 49(4):1609-19.

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Lee J, Sato MM, Coel MN, Lee KH, Kwee SA. Prediction of PSA Progression in Castration-Resistant Prostate Cancer Based on Treatment-Associated Change in Tumor Burden Quantified by 18F-Fluorocholine PET/CT. J Nucl Med. 2016 07; 57(7):1058-64.

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Suh JH, Chattopadhyay A, Sieglaff DH, Storer Samaniego C, Cox MB, Webb P. Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists. PLoS One. 2015; 10(9):e0137103.

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Sammon JD, Abdollah F, Reznor G, Pucheril D, Choueiri TK, Hu JC, Kim SP, Schmid M, Sood A, Sun M, Kibel AS, Nguyen PL, Menon M, Trinh QD. Patterns of Declining Use and the Adverse Effect of Primary Androgen Deprivation on All-cause Mortality in Elderly Men with Prostate Cancer. Eur Urol. 2015 Jul; 68(1):32-9.

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Fossati N, Trinh QD, Sammon J, Sood A, Larcher A, Sun M, Karakiewicz P, Guazzoni G, Montorsi F, Briganti A, Menon M, Abdollah F. Identifying optimal candidates for local treatment of the primary tumor among patients diagnosed with metastatic prostate cancer: a SEER-based study. Eur Urol. 2015 Jan; 67(1):3-6.

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