"Amphetamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
| Descriptor ID |
D000661
|
| MeSH Number(s) |
D02.092.471.683.152.110
|
| Concept/Terms |
Amphetamine- Amphetamine
- Amfetamine
- Phenopromin
- Desoxynorephedrin
- Phenamine
l-Amphetamine- l-Amphetamine
- l Amphetamine
- levo-Amphetamine
- levo Amphetamine
- Levoamphetamine
|
Below are MeSH descriptors whose meaning is more general than "Amphetamine".
Below are MeSH descriptors whose meaning is more specific than "Amphetamine".
This graph shows the total number of publications written about "Amphetamine" by people in this website by year, and whether "Amphetamine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 1 | 3 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amphetamine" by people in Profiles.
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Garcia V, Collins SA, Hernandez E, Cruz A, Vasquez A, Sweeney AM, Perez RA, Brito BN, Morera OF, Casta?eda E. A proposed mechanism for amphetamine-induced behavioral sensitization involving the vesicular monoamine transporter. Brain Res. 2025 Oct 15; 1865:149848.
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Gatica RI, P?rez-Valenzuela E, Sierra-Mercado D, Fuentealba JA. The expression of amphetamine sensitization is dissociable from anxiety and aversive memory: Effect of an acute injection of amphetamine. Neurosci Lett. 2017 01 18; 638:21-26.
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Butler B, Saha K, Rana T, Becker JP, Sambo D, Davari P, Goodwin JS, Khoshbouei H. Dopamine Transporter Activity Is Modulated by a-Synuclein. J Biol Chem. 2015 Dec 04; 290(49):29542-54.
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Yu PL, Cheng SY, Chou JC, Pan WH, Wang SW, Wang PS. Regulation of Intermittent Hypoxia on Brain Dopamine in Amphetaminized Rats. Chin J Physiol. 2015 Aug 31; 58(4):219-27.
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Williams SN, Undieh AS. Dopamine-sensitive signaling mediators modulate psychostimulant-induced ultrasonic vocalization behavior in rats. Behav Brain Res. 2016 Jan 01; 296:1-6.
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Aguilar-Rivera MI, Casanova JP, Gatica RI, Quirk GJ, Fuentealba JA. Amphetamine sensitization is accompanied by an increase in prelimbic cortex activity. Neuroscience. 2015 Mar 12; 288:1-9.
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Miczek KA, Nikulina EM, Takahashi A, Covington HE, Yap JJ, Boyson CO, Shimamoto A, de Almeida RM. Gene expression in aminergic and peptidergic cells during aggression and defeat: relevance to violence, depression and drug abuse. Behav Genet. 2011 Nov; 41(6):787-802.
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Terplan M, Wright T. The effects of cocaine and amphetamine use during pregnancy on the newborn: myth versus reality. J Addict Dis. 2011 Jan; 30(1):1-5.
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Yu PL, Wu CI, Lee TS, Pan WH, Wang PS, Wang SW. Attenuation of estradiol on the reduction of striatal dopamine by amphetamine in ovariectomized rats. J Cell Biochem. 2009 Dec 15; 108(6):1318-24.
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Afonso VM, Mueller D, Stewart J, Pfaus JG. Amphetamine pretreatment facilitates appetitive sexual behaviors in the female rat. Psychopharmacology (Berl). 2009 Jul; 205(1):35-43.