Lyophilized Filovirus Glycoprotein Vaccines: Peroxides in a Vaccine Formulation with Polysorbate 80-Containing Adjuvant are Associated with Reduced Neutralizing Antibody Titers in Both Mice and Non-Human Primates.

Preston KB, Wong TAS, Lieberman MM, To A, Lai CY, Granados A, Thomasson H, Misamore J, Yalley-Ogunro J, Cabus M, Andersen H, Donini O, Lehrer AT, Randolph TW. Lyophilized Filovirus Glycoprotein Vaccines: Peroxides in a Vaccine Formulation with Polysorbate 80-Containing Adjuvant are Associated with Reduced Neutralizing Antibody Titers in Both Mice and Non-Human Primates. J Pharm Sci. 2022 12; 111(12):3424-3434.

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Axel Lehrer, PhD

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