Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.

Polyzos A, Holt A, Brown C, Cosme C, Wipf P, Gomez-Marin A, Castro MR, Ayala-Pe?a S, McMurray CT. Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes. Hum Mol Genet. 2016 05 01; 25(9):1792-802.

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subject areas

Animals
Behavior, Animal
Cells, Cultured
Cyclic N-Oxides
Disease Models, Animal
Huntington Disease
Mice
Mice, Inbred C57BL
Mitochondria
Motor Activity
Neurons
Oxidative Stress
Weight Loss

authors with profiles

Sylvette Ayala-Peña

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