Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.

Lau AW, Inuzuka H, Fukushima H, Wan L, Liu P, Gao D, Sun Y, Wei W. Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. Cell Res. 2013 Jul; 23(7):947-61.

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subject areas

Animals
Cell Line
Cell Line, Tumor
Cell Movement
Cyclin E
Humans
Immunoblotting
Immunoprecipitation
Male
Mice
Models, Biological
Phosphorylation
Reverse Transcriptase Polymerase Chain Reaction
SKP Cullin F-Box Protein Ligases
Ubiquitination

authors with profiles

Alan F. Lau, PhD

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