An alphavirus vector-based tetravalent dengue vaccine induces a rapid and protective immune response in macaques that differs qualitatively from immunity induced by live virus infection.

White LJ, Sariol CA, Mattocks MD, Wahala M P B W, Yingsiwaphat V, Collier ML, Whitley J, Mikkelsen R, Rodriguez IV, Martinez MI, de Silva A, Johnston RE. An alphavirus vector-based tetravalent dengue vaccine induces a rapid and protective immune response in macaques that differs qualitatively from immunity induced by live virus infection. J Virol. 2013 Mar; 87(6):3409-24.

View in: PubMed

subject areas

Animals
Antibodies, Neutralizing
Antibodies, Viral
Cross Reactions
Dengue
Dengue Vaccines
Disease Models, Animal
Drug Carriers
Encephalitis Virus, Venezuelan Equine
Genetic Vectors
Macaca
Vaccines, Synthetic
Viremia

authors with profiles

Carlos A. Sariol, M.D.

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support