Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis.

Cinar M, Hamedani F, Mo Z, Cinar B, Amin HM, Alkan S. Bruton tyrosine kinase is commonly overexpressed in mantle cell lymphoma and its attenuation by Ibrutinib induces apoptosis. Leuk Res. 2013 Oct; 37(10):1271-7.

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subject areas

Adenine
Apoptosis
Cell Line
Cell Survival
Gene Expression
Gene Expression Regulation, Neoplastic
Humans
Immunophenotyping
Lymphoma, Mantle-Cell
Phosphorylation
Piperidines
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-bcl-2
Pyrazoles
Pyrimidines

authors with profiles

Bekir Cinar

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