A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells.

Aneja R, Miyagi T, Karna P, Ezell T, Shukla D, Vij Gupta M, Yates C, Chinni SR, Zhau H, Chung LW, Joshi HC. A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells. Eur J Cancer. 2010 Jun; 46(9):1668-78.

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subject areas

Animals
Apoptosis
Caspase 3
Cell Line, Tumor
Dioxoles
G2 Phase
Humans
Isoquinolines
Male
Mice
Mice, Inbred BALB C
Mice, Nude
Mitochondria
Mitosis
Prostatic Neoplasms
Tubulin Modulators
Xenograft Model Antitumor Assays

authors with profiles

Clayton Yates

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