Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.

Taylor JG, Cheuk AT, Tsang PS, Chung JY, Song YK, Desai K, Yu Y, Chen QR, Shah K, Youngblood V, Fang J, Kim SY, Yeung C, Helman LJ, Mendoza A, Ngo V, Staudt LM, Wei JS, Khanna C, Catchpoole D, Qualman SJ, Hewitt SM, Merlino G, Chanock SJ, Khan J. Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models. J Clin Invest. 2009 Nov; 119(11):3395-407.

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subject areas

Animals
Cell Cycle
Cell Line, Transformed
Cell Line, Tumor
Cell Proliferation
Disease Models, Animal
DNA Replication
Humans
Lung Neoplasms
Mice
Models, Molecular
Mutation
Neoplasm Metastasis
Phosphorylation
Protein Structure, Tertiary
Receptor, Fibroblast Growth Factor, Type 4
Rhabdomyosarcoma
STAT3 Transcription Factor
Transplantation, Heterologous

authors with profiles

James Taylor

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