Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety.

Lan A, Li W, Liu Y, Xiong Z, Zhang X, Zhou S, Palko O, Chen H, Kapita M, Prigge JR, Schmidt EE, Chen X, Sun Z, Chen XL. Chemoprevention of oxidative stress-associated oral carcinogenesis by sulforaphane depends on NRF2 and the isothiocyanate moiety. Oncotarget. 2016 Aug 16; 7(33):53502-53514.

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subject areas

4-Nitroquinoline-1-oxide
Animals
Anticarcinogenic Agents
Carcinogens
Chemoprevention
Humans
Isothiocyanates
Mice
Mice, Knockout
Mouth Neoplasms
NF-E2-Related Factor 2
Oxidative Stress
Sulfoxides

authors with profiles

Luke Chen

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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