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Youssef Roman, PharmD, PhD

TitleResearcher
Faculty RankAssistant Professor
InstitutionUniversity of Hawaii at Manoa
DepartmentPharmaceutical Sciences
AddressUniversity of Hawaii at Hilo
The Daniel K. Inouye College of Pharmacy
34 Rainbow Drive
Hilo HI 96720
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Carter MW, Roman YM. Perspectives on the Epidemiology of Hyperuricemia and Gout in Older Adults. Sr Care Pharm. 2025 Sep 01; 40(9):365-372. PMID: 40886040.
      Citations:    Fields:    Translation:Humans
    2. Nieh HV, Roman YM. Major Allele Frequencies in CYP2C9 and CYP2C19 in Asian and European Populations: A Case Study to Disaggregate Data Among Large Racial Categories. J Pers Med. 2025 Jun 27; 15(7). PMID: 40710391.
      Citations:    
    3. Roman Y. Bridging the United States population diversity gaps in clinical research: roadmap to precision health and reducing health disparities. Per Med. 2025 Jun; 22(3):193-203. PMID: 40358454.
      Citations: 2     Fields:    Translation:Humans
    4. Pressly MA, Schuck R, Mummaneni P, Roman YM, Pacanowski M. Utilization of polygenic risk scores in drug development protocols. Pharmacogenomics. 2025 Feb-Mar; 26(3-4):75-79. PMID: 40200755.
      Citations:    Fields:    Translation:Humans
    5. Roman YM. Pharmacogenomics and rare diseases: optimizing drug development and personalized therapeutics. Pharmacogenomics. 2025 Feb-Mar; 26(3-4):121-128. PMID: 40194983.
      Citations:    Fields:    Translation:Humans
    6. Smith J, Martin A, Mundadan J, Roberts M, Roman Y, Bravo-Nuevo A, Daghigh F. Exploring the prevalence of gout among underrepresented low socioeconomic status type 2 diabetes populations. Diabetol Metab Syndr. 2025 Jan 21; 17(1):25. PMID: 39833933.
      Citations:    
    7. Roman Y. Correlation of systemic immune inflammation and serum uric acid with gout: based on NHANES. Clin Rheumatol. 2025 Mar; 44(3):1393-1394. PMID: 39821127.
      Citations:    Fields:    
    8. Ahmed MA, Krishna R, Rayad N, Albusaysi S, Mitra A, Shang E, Hon YY, AbuAsal B, Bakhaidar R, Roman YM, Bhattacharya I, Cloyd J, Patel M, Kartha RV, Younis IR. Getting the Dose Right in Drug Development for Rare Diseases: Barriers and Enablers. Clin Pharmacol Ther. 2024 Dec; 116(6):1412-1432. PMID: 39148459.
      Citations: 5     Fields:    Translation:HumansAnimals
    9. Sargent L, Zimmerman KM, Mohammed A, Barrett MJ, Nawaz H, Wyman-Chick K, Mackiewicz M, Roman Y, Slattum P, Russell S, Dixon DL, Lageman SK, Hobgood S, Thacker LR, Price ET. Low-Income Older Adults' Vulnerability to Anticholinergic Medication-Associated Frailty. Drugs Aging. 2023 12; 40(12):1123-1131. PMID: 37856064.
      Citations: 2     Fields:    Translation:Humans
    10. Diallo AF, Mackiewicz M, Sargent L, Roman YM, Slattum PW, Waters L, Bennett J, Battle K, Zanjani F, Gendron T, Winship J, Ford G, Falls K, Price ET, Parsons P, Chung J. Cultivating Relationships as a Community-Based Recruitment Strategy in Transdisciplinary Aging Research: Lessons From an Academic-Community Partnership. Fam Community Health. 2024 Jan-Mar 01; 47(1):32-40. PMID: 37831622.
      Citations: 1     Fields:    Translation:Humans
    11. Roman YM. The Role of Uric Acid in Human Health: Insights from the Uricase Gene. J Pers Med. 2023 Sep 20; 13(9). PMID: 37763176.
      Citations:    
    12. Hang Y, Lee C, Roman YM. Assessing the clinical utility of major indices for nonalcoholic fatty liver disease in East?Asian populations. Biomark Med. 2023 04; 17(8):445-454. PMID: 37449859.
      Citations: 1     Fields:    Translation:Humans
    13. Mitra A, Ahmed MA, Krishna R, Sun K, Gibbons FD, Campagne O, Rayad N, Roman YM, Albusaysi S, Burian M, Younis IR. Model-Informed Approaches and Innovative Clinical Trial Design for Adeno-Associated Viral Vector-Based Gene Therapy Product Development: A White Paper. Clin Pharmacol Ther. 2023 09; 114(3):515-529. PMID: 37313953.
      Citations: 3     Fields:    
    14. Roman YM. Editorial: The role of pharmacogenomics in addressing health disparities: the path, the promise, and the barriers. Front Genet. 2023; 14:1233045. PMID: 37359365.
      Citations:    
    15. Wen YF, Brundage RC, Roman YM, Culhane-Pera KA, Straka RJ. Population pharmacokinetics, pharmacodynamics and pharmacogenetics modelling of oxypurinol in Hmong adults with gout and/or hyperuricemia. Br J Clin Pharmacol. 2023 10; 89(10):2964-2976. PMID: 37202871.
      Citations: 1     Fields:    Translation:Humans
    16. Vo V, Lopez G, Malay S, Roman YM. Cardiovascular Risk Factors Among Asian Americans: Perspectives on the Role of Acculturation in Cardiovascular Diseases Health Disparities. J Immigr Minor Health. 2024 Apr; 26(2):409-420. PMID: 37222869.
      Citations: 7     Fields:    Translation:Humans
    17. Alrajeh K, AlAzzeh O, Roman Y. The frequency of major ABCG2, SLCO1B1 and CYP2C9 variants in Asian, Native Hawaiian and Pacific Islander women subgroups: implications for personalized statins dosing. Pharmacogenomics. 2023 05; 24(7):381-398. PMID: 37222158.
      Citations: 4     Fields:    Translation:Humans
    18. AlAzzeh O, Roman YM. The frequency of rs2231142 in ABCG2 among Native Hawaiian and Pacific Islander subgroups: implications for personalized rosuvastatin dosing. Pharmacogenomics. 2023 02; 24(3):173-182. PMID: 36661065.
      Citations: 7     Fields:    Translation:Humans
    19. Alrajeh K, Roman YM. The frequency of rs2231142 in ABCG2?among Asian subgroups: implications for personalized rosuvastatin dosing. Pharmacogenomics. 2023 01; 24(1):15-26. PMID: 36651271.
      Citations: 6     Fields:    Translation:Humans
    20. Roman YM. Moving the Needle in Gout Management: The Role of Culture, Diet, Genetics, and Personalized Patient Care Practices. Nutrients. 2022 Aug 31; 14(17). PMID: 36079846.
      Citations: 12     Fields:    Translation:Humans
    21. Roman YM. COVID-19 pandemic: the role of community-based pharmacy practice in health equity. Int J Clin Pharm. 2022 Oct; 44(5):1211-1215. PMID: 35764850.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    22. Alrajeh KY, Roman YM. The frequency of major CYP2C19 genetic polymorphisms in women of Asian, Native Hawaiian?and Pacific Islander subgroups. Per Med. 2022 07; 19(4):327-339. PMID: 35748236.
      Citations: 10     Fields:    Translation:Humans
    23. Roman Y. Pathway for ascertaining the role of uric acid in neurodegenerative diseases. Alzheimers Dement (Amst). 2022; 14(1):e12329. PMID: 35769871.
      Citations:    
    24. Roman YM, McClish D, Price ET, Sabo RT, Woodward OM, Mersha TB, Shah N, Armada A, Terkeltaub R. Cardiometabolic genomics and pharmacogenomics investigations in Filipino Americans: Steps towards precision health and reducing health disparities. Am Heart J Plus. 2022 Mar; 15. PMID: 35647570.
      Citations:    
    25. Anderson AN, Chan AR, Roman YM. Pharmacogenomics and clinical cultural competency: pathway to overcome the limitations of race. Pharmacogenomics. 2022 04; 23(6):363-370. PMID: 35311348.
      Citations: 4     Fields:    Translation:Humans
    26. Alghubayshi A, Edelman A, Alrajeh K, Roman Y. Genetic assessment of hyperuricemia and gout in Asian, Native Hawaiian, and Pacific Islander subgroups of pregnant women: biospecimens repository cross-sectional study. BMC Rheumatol. 2022 Jan 06; 6(1):1. PMID: 34986901.
      Citations:    
    27. Coronado G, Chio-Lauri J, Cruz RD, Roman YM. Health Disparities of Cardiometabolic Disorders Among Filipino Americans: Implications for Health Equity and Community-Based Genetic Research. J Racial Ethn Health Disparities. 2022 12; 9(6):2560-2567. PMID: 34837163.
      Citations: 16     Fields:    Translation:Humans
    28. Roman Y. The United States 2020 Census data: implications for precision medicine and the?research landscape. Per Med. 2022 01; 19(1):5-8. PMID: 34747188.
      Citations: 15     Fields:    Translation:Humans
    29. Roman YM, Lor K, Xiong T, Culhane-Pera K, Straka RJ. Gout prevalence in the Hmong: a?prime example of health disparity and the role of community-based genetic research. Per Med. 2021 05; 18(3):311-327. PMID: 33787318.
      Citations: 9     Fields:    Translation:Humans
    30. Roman YM. Pathway to Ascertain the Role of Pharmacogenomics in Healthcare Utilization Outcomes [Letter]. Pharmgenomics Pers Med. 2021; 14:379-380. PMID: 33814924.
      Citations:    
    31. Butler F, Alghubayshi A, Roman Y. The Epidemiology and Genetics of Hyperuricemia and Gout across Major Racial Groups: A Literature Review and Population Genetics Secondary Database Analysis. J Pers Med. 2021 Mar 22; 11(3). PMID: 33810064.
      Citations:    
    32. J Sargent L, Mackiewicz M, Roman Y, Diallo A, Russell S, Falls K, Zimmerman KM, Dixon DL, Prom-Wormley E, Hobgood S, Lageman SK, Zanjani F, Price ET. The Translational Approaches to Personalized Health Collaborative: Pharmacogenomics for African American Older Adults. Clin Transl Sci. 2021 03; 14(2):437-444. PMID: 33026148.
      Citations: 1     Fields:    Translation:Humans
    33. Roman YM, Dixon DL, Salgado TM, Price ET, Zimmerman KM, Sargent L, Slattum PW. Challenges in pharmacotherapy for older adults: a framework for pharmacogenomics implementation. Pharmacogenomics. 2020 06; 21(9):627-635. PMID: 32425117.
      Citations: 6     Fields:    Translation:Humans
    34. Roman Y, Tiirikainen M, Prom-Wormley E. The prevalence of the gout-associated polymorphism rs2231142 G>T in ABCG2 in a pregnant female Filipino cohort. Clin Rheumatol. 2020 Aug; 39(8):2387-2392. PMID: 32107664.
      Citations: 16     Fields:    Translation:Humans
    35. Peng K, Bjork J, Wen YF, Roman YM, Culhane-Pera K, Lo MX, Gertner E, Straka RJ. HLA-B*58: 01 carrier status of Hmong in Minnesota: first in Hmong genotyping for prevalence of this biomarker of risk for severe cutaneous adverse reactions caused by allopurinol. Pharmacogenet Genomics. 2020 02; 30(2):21-25. PMID: 31658186.
      Citations: 1     Fields:    Translation:Humans
    36. Roman YM. The Daniel K. Inouye College of Pharmacy Scripts: Perspectives on the Epidemiology of Gout and Hyperuricemia. Hawaii J Med Public Health. 2019 02; 78(2):71-76. PMID: 30766768.
      Citations: 20     Fields:    Translation:Humans
    37. Roman YM. Race and precision medicine: is it time for an upgrade? Pharmacogenomics J. 2019 02; 19(1):1-4. PMID: 30197415.
      Citations: 8     Fields:    Translation:Humans
    38. Culhane-Pera KA, Straka RJ, Moua M, Roman Y, Vue P, Xiaaj K, Lo MX, Lor M. Engaging Hmong adults in genomic?and?pharmacogenomic research: Toward reducing health disparities in genomic knowledge using a community-based participatory research approach. J Community Genet. 2017 Apr; 8(2):117-125. PMID: 28074382.
      Citations:    
    39. Roman YM, Culhane-Pera KA, Menk J, Straka RJ. Assessment of genetic polymorphisms associated with hyperuricemia or gout in the Hmong. Per Med. 2016 Sep; 13(5):429-440. PMID: 28781600.
      Citations: 14     Fields:    
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