Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy.

Xue J, Patergnani S, Giorgi C, Suarez J, Goto K, Bononi A, Tanji M, Novelli F, Pastorino S, Xu R, Caroccia N, Dogan AU, Pass HI, Tognon M, Pinton P, Gaudino G, Mak TW, Carbone M, Yang H. Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25543-25552.

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subject areas

Adult
Aged
Animals
Asbestos
Autophagy
Cell Transformation, Neoplastic
Cells, Cultured
Epithelial Cells
HMGB1 Protein
Humans
Male
Mesothelioma
Mice
Mice, Knockout
Middle Aged
Occupational Exposure

authors with profiles

Michele Carbone, MD, PhD.
Sandra Pastorino, PhD

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