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Thomas E. Wiese

TitleAssociate Professor, Department of Chemistry
InstitutionXavier University of Louisiana
Departmentcollege of pharmacy
AddressXavier University
College of Pharmacy
Room 309
New Orleans LA 70125
Phone(504) 520-7433
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Guo S, Zhang C, Bratton M, Mottamal M, Liu J, Ma P, Zheng S, Zhong Q, Yang L, Wiese TE, Wu Y, Ellis MJ, Matossian M, Burow ME, Miele L, Houtman R, Wang G. ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models. Oncotarget. 2018 Jan 23; 9(6):6924-6937. PMID: 29467940.
      Citations: 2     Fields:    
    2. Powell D, Chandra S, Dodson K, Shaheen F, Wiltz K, Ireland S, Syed M, Dash S, Wiese T, Mandal T, Kundu A. Aptamer-functionalized hybrid nanoparticle for the treatment of breast cancer. Eur J Pharm Biopharm. 2017 May; 114:108-118. PMID: 28131717.
      Citations: 4     Fields:    Translation:HumansCells
    3. Townley IK, Karchner SI, Skripnikova E, Wiese TE, Hahn ME, Rees BB. Sequence and functional characterization of hypoxia-inducible factors, HIF1a, HIF2aa, and HIF3a, from the estuarine fish, Fundulus heteroclitus. Am J Physiol Regul Integr Comp Physiol. 2017 03 01; 312(3):R412-R425. PMID: 28039194.
      Citations:    Fields:    Translation:AnimalsCells
    4. Liu J, Zheng S, Guo S, Zhang C, Zhong Q, Zhang Q, Ma P, Skripnikova EV, Bratton MR, Wiese TE, Wang G. Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator. ACS Med Chem Lett. 2017 Jan 12; 8(1):102-106. PMID: 28105283.
    5. Liu J, Zheng S, Akerstrom VL, Yuan C, Ma Y, Zhong Q, Zhang C, Zhang Q, Guo S, Ma P, Skripnikova EV, Bratton MR, Pannuti A, Miele L, Wiese TE, Wang G. Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD). J Med Chem. 2016 09 08; 59(17):8134-40. PMID: 27529700.
      Citations: 10     Fields:    Translation:AnimalsCells
    6. Liu J, Pham PT, Skripnikova EV, Zheng S, Lovings LJ, Wang Y, Goyal N, Bellow SM, Mensah LM, Chatters AJ, Bratton MR, Wiese TE, Zhao M, Wang G, Foroozesh M. A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2. J Med Chem. 2015 Aug 27; 58(16):6481-93. PMID: 26222195.
      Citations: 1     Fields:    Translation:HumansCells
    7. Bratton MR, Martin EC, Elliott S, Rhodes LV, Collins-Burow BM, McLachlan JA, Wiese TE, Boue SM, Burow ME. Glyceollin, a novel regulator of mTOR/p70S6 in estrogen receptor positive breast cancer. J Steroid Biochem Mol Biol. 2015 Jun; 150:17-23. PMID: 25771071.
      Citations: 4     Fields:    Translation:HumansCells
    8. Sun Y, Miller CA, Wiese TE, Blake DA. Methylated phenanthrenes are more potent than phenanthrene in a bioassay of human aryl hydrocarbon receptor (AhR) signaling. Environ Toxicol Chem. 2014 Oct; 33(10):2363-7. PMID: 25043914.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    9. Wells KJ, Lima DS, Meade CD, Muñoz-Antonia T, Scarinci I, McGuire A, Gwede CK, Pledger WJ, Partridge E, Lipscomb J, Matthews R, Matta J, Flores I, Weiner R, Turner T, Miele L, Wiese TE, Fouad M, Moreno CS, Lacey M, Christie DW, Price-Haywood EG, Quinn GP, Coppola D, Sodeke SO, Green BL, Lichtveld MY. Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities. Eval Program Plann. 2014 Jun; 44:14-25. PMID: 24486917.
      Citations: 7     Fields:    Translation:Humans
    10. Cao B, Liu X, Li J, Liu S, Qi Y, Xiong Z, Zhang A, Wiese T, Fu X, Gu J, Rennie PS, Sartor O, Lee BR, Ip C, Zhao L, Zhang H, Dong Y. 20(S)-protopanaxadiol-aglycone downregulation of the full-length and splice variants of androgen receptor. Int J Cancer. 2013 Mar 15; 132(6):1277-87. PMID: 22907191.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    11. Bratton MR, Frigo DE, Segar HC, Nephew KP, McLachlan JA, Wiese TE, Burow ME. The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells. Environ Health Perspect. 2012 Sep; 120(9):1291-6. PMID: 22609851.
      Citations: 6     Fields:    Translation:HumansCells
    12. Tilghman SL, Bratton MR, Segar HC, Martin EC, Rhodes LV, Li M, McLachlan JA, Wiese TE, Nephew KP, Burow ME. Endocrine disruptor regulation of microRNA expression in breast carcinoma cells. PLoS One. 2012; 7(3):e32754. PMID: 22403704.
      Citations: 38     Fields:    Translation:HumansCells
    13. Antoon JW, Meacham WD, Bratton MR, Slaughter EM, Rhodes LV, Ashe HB, Wiese TE, Burow ME, Beckman BS. Pharmacological inhibition of sphingosine kinase isoforms alters estrogen receptor signaling in human breast cancer. J Mol Endocrinol. 2011 Jun; 46(3):205-16. PMID: 21321095.
      Citations: 25     Fields:    Translation:HumansCells
    14. Khupse RS, Sarver JG, Trendel JA, Bearss NR, Reese MD, Wiese TE, Boue SM, Burow ME, Cleveland TE, Bhatnagar D, Erhardt PW. Biomimetic syntheses and antiproliferative activities of racemic, natural (-), and unnnatural (+) glyceollin I. J Med Chem. 2011 May 26; 54(10):3506-23. PMID: 21513275.
      Citations: 3     Fields:    Translation:HumansCells
    15. Boué SM, Burow ME, Wiese TE, Shih BY, Elliott S, Carter-Wientjes CH, McLachlan JA, Bhatnagar D. Estrogenic and antiestrogenic activities of phytoalexins from red kidney bean (Phaseolus vulgaris L.). J Agric Food Chem. 2011 Jan 12; 59(1):112-20. PMID: 21133423.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    16. Antoon JW, White MD, Meacham WD, Slaughter EM, Muir SE, Elliott S, Rhodes LV, Ashe HB, Wiese TE, Smith CD, Burow ME, Beckman BS. Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640. Endocrinology. 2010 Nov; 151(11):5124-35. PMID: 20861237.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    17. Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G. Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells. J Med Chem. 2010 Aug 26; 53(16):6153-63. PMID: 20669983.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    18. Payton-Stewart F, Khupse RS, Boué SM, Elliott S, Zimmermann MC, Skripnikova EV, Ashe H, Tilghman SL, Beckman BS, Cleveland TE, McLachlan JA, Bhatnagar D, Wiese TE, Erhardt P, Burow ME. Glyceollin I enantiomers distinctly regulate ER-mediated gene expression. Steroids. 2010 Dec; 75(12):870-8. PMID: 20493896.
      Citations: 8     Fields:    Translation:HumansCells
    19. Zimmermann MC, Tilghman SL, Boué SM, Salvo VA, Elliott S, Williams KY, Skripnikova EV, Ashe H, Payton-Stewart F, Vanhoy-Rhodes L, Fonseca JP, Corbitt C, Collins-Burow BM, Howell MH, Lacey M, Shih BY, Carter-Wientjes C, Cleveland TE, McLachlan JA, Wiese TE, Beckman BS, Burow ME. Glyceollin I, a novel antiestrogenic phytoalexin isolated from activated soy. J Pharmacol Exp Ther. 2010 Jan; 332(1):35-45. PMID: 19797619.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    20. Rees BB, Figueroa YG, Wiese TE, Beckman BS, Schulte PM. A novel hypoxia-response element in the lactate dehydrogenase-B gene of the killifish Fundulus heteroclitus. Comp Biochem Physiol A Mol Integr Physiol. 2009 Sep; 154(1):70-7. PMID: 19439190.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    21. Boué SM, Tilghman SL, Elliott S, Zimmerman MC, Williams KY, Payton-Stewart F, Miraflor AP, Howell MH, Shih BY, Carter-Wientjes CH, Segar C, Beckman BS, Wiese TE, Cleveland TE, McLachlan JA, Burow ME. Identification of the potent phytoestrogen glycinol in elicited soybean (Glycine max). Endocrinology. 2009 May; 150(5):2446-53. PMID: 19116342.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    22. Zhou C, Nitschke AM, Xiong W, Zhang Q, Tang Y, Bloch M, Elliott S, Zhu Y, Bazzone L, Yu D, Weldon CB, Schiff R, McLachlan JA, Beckman BS, Wiese TE, Nephew KP, Shan B, Burow ME, Wang G. Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype. Breast Cancer Res. 2008; 10(6):R105. PMID: 19087274.
      Citations: 50     Fields:    Translation:Humans
    23. Vu H, Ianosi-Irimie M, Danchuk S, Rabon E, Nogawa T, Kamano Y, Pettit GR, Wiese T, Puschett JB. Resibufogenin corrects hypertension in a rat model of human preeclampsia. Exp Biol Med (Maywood). 2006 Feb; 231(2):215-20. PMID: 16446498.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    24. Boué SM, Wiese TE, Nehls S, Burow ME, Elliott S, Carter-Wientjes CH, Shih BY, McLachlan JA, Cleveland TE. Evaluation of the estrogenic effects of legume extracts containing phytoestrogens. J Agric Food Chem. 2003 Apr 09; 51(8):2193-9. PMID: 12670155.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    25. Rubin VN, Ruenitz PC, Boyd JL, Boudinot FD, Wiese TE. Characterization of selective estrogen receptor modulator (SERM) activity in two triarylethylene oxybutyric acids. Biochem Pharmacol. 2002 Apr 15; 63(8):1517-25. PMID: 11996894.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    26. Burow ME, Boue SM, Collins-Burow BM, Melnik LI, Duong BN, Carter-Wientjes CH, Li S, Wiese TE, Cleveland TE, McLachlan JA. Phytochemical glyceollins, isolated from soy, mediate antihormonal effects through estrogen receptor alpha and beta. J Clin Endocrinol Metab. 2001 Apr; 86(4):1750-8. PMID: 11297613.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    27. Bolger R, Wiese TE, Ervin K, Nestich S, Checovich W. Rapid screening of environmental chemicals for estrogen receptor binding capacity. Environ Health Perspect. 1998 Sep; 106(9):551-7. PMID: 9721254.
      Citations: 35     Fields:    Translation:Humans
    28. Wiese TE, Polin LA, Palomino E, Brooks SC. Induction of the estrogen specific mitogenic response of MCF-7 cells by selected analogues of estradiol-17 beta: a 3D QSAR study. J Med Chem. 1997 Oct 24; 40(22):3659-69. PMID: 9357533.
      Citations: 7     Fields:    Translation:HumansCells
    29. Gray LE, Kelce WR, Wiese T, Tyl R, Gaido K, Cook J, Klinefelter G, Desaulniers D, Wilson E, Zacharewski T, Waller C, Foster P, Laskey J, Reel J, Giesy J, Laws S, McLachlan J, Breslin W, Cooper R, Di Giulio R, Johnson R, Purdy R, Mihaich E, Safe S, Colborn T, et al. Endocrine Screening Methods Workshop report: detection of estrogenic and androgenic hormonal and antihormonal activity for chemicals that act via receptor or steroidogenic enzyme mechanisms. Reprod Toxicol. 1997 Sep-Oct; 11(5):719-50. PMID: 9311581.
      Citations: 15     Fields:    Translation:HumansAnimals
    30. Waller CL, Oprea TI, Chae K, Park HK, Korach KS, Laws SC, Wiese TE, Kelce WR, Gray LE. Ligand-based identification of environmental estrogens. Chem Res Toxicol. 1996 Dec; 9(8):1240-8. PMID: 8951225.
      Citations: 21     Fields:    Translation:AnimalsCells
    31. Wiese TJ, Wuensch SA, Ray PD. Synthesis of citrate from phosphoenolpyruvate and acetylcarnitine by mitochondria from rabbit, pigeon and rat liver: implications for lipogenesis. Comp Biochem Physiol B Biochem Mol Biol. 1996 Aug; 114(4):417-22. PMID: 8840517.
      Citations: 1     Fields:    Translation:AnimalsCells
    32. Wiese TE, Dukes D, Brooks SC. A molecular modeling analysis of diethylstilbestrol conformations and their similarity to estradiol-17 beta. Steroids. 1995 Dec; 60(12):802-8. PMID: 8650702.
      Citations:    Fields:    Translation:Cells
    33. Wiese TJ, Dunlap JA, Yorek MA. L-fucose is accumulated via a specific transport system in eukaryotic cells. J Biol Chem. 1994 Sep 09; 269(36):22705-11. PMID: 8077222.
      Citations: 6     Fields:    Translation:AnimalsCells
    34. Wiese TE, Brooks SC. Molecular modeling of steroidal estrogens: novel conformations and their role in biological activity. J Steroid Biochem Mol Biol. 1994 Jul; 50(1-2):61-73. PMID: 8049135.
      Citations: 3     Fields:    Translation:Cells
    35. Horwitz JP, Massova I, Wiese TE, Besler BH, Corbett TH. Comparative molecular field analysis of the antitumor activity of 9H-thioxanthen-9-one derivatives against pancreatic ductal carcinoma 03. J Med Chem. 1994 Mar 18; 37(6):781-6. PMID: 8145227.
      Citations: 7     Fields:    Translation:AnimalsCells
    36. Horwitz JP, Massova I, Wiese TE, Wozniak AJ, Corbett TH, Sebolt-Leopold JS, Capps DB, Leopold WR. Comparative molecular field analysis of in vitro growth inhibition of L1210 and HCT-8 cells by some pyrazoloacridines. J Med Chem. 1993 Nov 12; 36(23):3511-6. PMID: 8280289.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    37. VanderKuur JA, Wiese T, Brooks SC. Influence of estrogen structure on nuclear binding and progesterone receptor induction by the receptor complex. Biochemistry. 1993 Jul 13; 32(27):7002-8. PMID: 8334129.
      Citations: 4     Fields:    Translation:HumansCells
    38. Wiese TE, Kral LG, Dennis KE, Butler WB, Brooks SC. Optimization of estrogen growth response in MCF-7 cells. In Vitro Cell Dev Biol. 1992 Sep-Oct; 28A(9-10):595-602. PMID: 1429362.
      Citations: 14     Fields:    Translation:HumansCells
    39. Wiese TJ, Lambeth DO, Ray PD. The intracellular distribution and activities of phosphoenolpyruvate carboxykinase isozymes in various tissues of several mammals and birds. Comp Biochem Physiol B. 1991; 100(2):297-302. PMID: 1799972.
      Citations: 14     Fields:    Translation:AnimalsCells
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