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Olorunseun Ogunwobi

Faculty RankAssociate Professor
InstitutionHunter College, CUNY
DepartmentBiological Sciences
Address695 Park Avenue
Room 932HN
New York NY 10065
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    2017Carnegie African Diaspora Fellowship, Carnegie Corporation of New York

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    The overall goal of our laboratory is to elucidate the mechanisms of metastasis in solid organ cancers. Ongoing studies include examination of the role of circulating tumor cell biology and epigenetics in the metastasis of solid organ cancers. Also, our laboratory is investigating the biological mechanisms underlying the racial disparities in specific solid organ cancers. The cancer models we are currently focused on are hepatocellular carcinoma, pancreatic cancer, colon cancer, and prostate cancer.
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    U54CA221704     (OGUNWOBI, OLORUNSEUN O)Sep 18, 2018 - Aug 31, 2023
    (2/2) TUFCCC/HC Regional Comprehensive Cancer Health Disparity Partnership
    Role: Principal Investigator

    U54CA221705     (MA, GRACE X.)Sep 19, 2018 - Aug 31, 2023
    1/2 TUFCCC/HC Regional Comprehensive Cancer Health Disparity Partnership
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Johnson CK, Leung MM, Ma GX, Ogunwobi OO. Effective Recruitment Strategies Utilized to Examine Dietary Practices of Blacks in New York City in the Midst of the COVID-19 Pandemic. J Racial Ethn Health Disparities. 2023 Mar 16. PMID: 36929490.
      Citations:    Fields:    
    2. Ma GX, Zhu L, Tan Y, Zhai S, Ma X, Ogunwobi OO, Yang WJ, Ting T, Kim S, Wang MQ. A Comparative Trial of Improving Care for Underserved Asian Americans Infected with Hepatitis B Virus. Dig Dis Sci. 2023 Feb 07. PMID: 36749506.
      Citations:    Fields:    
    3. Vickers AJ, Mahal B, Ogunwobi OO. Racism Does Not Cause Prostate Cancer, It Causes Prostate Cancer Death. J Clin Oncol. 2023 Jan 24; JCO2202203. PMID: 36693227.
      Citations:    Fields:    
    4. Zambrano CN, Lu W, Johnson C, Beeber M, Panitz A, Ibrahim S, Fraser M, Ma GX, Navder K, Yeh MC, Ogunwobi OO. Dietary behavior and urinary gallic acid concentration differences among underserved elder racial and ethnic minorities in New York City. Cancer Causes Control. 2022 Jul; 33(7):929-937. PMID: 35438359.
      Citations:    Fields:    Translation:HumansAnimals
    5. Awah CU, Winter J, Ogunwobi OO. Genome scale CRISPR Cas9a knockout screen reveals genes that control glioblastoma susceptibility to the alkylating agent temozolomide. All Life. 2022; 15(1):88-93. PMID: 35990011.
    6. Akingboye A, Mahmood F, Amiruddin N, Reay M, Nightingale P, Ogunwobi OO. Increased risk of COVID-19-related admissions in patients with active solid organ cancer in the West Midlands region of the UK: a retrospective cohort study. BMJ Open. 2021 12 13; 11(12):e053352. PMID: 34903546.
      Citations: 2     Fields:    Translation:HumansCells
    7. Awah CU, Winter J, Mazdoom CM, Ogunwobi OO. NSUN6, an RNA methyltransferase of 5-mC controls glioblastoma response to temozolomide (TMZ) via NELFB and RPS6KB2 interaction. Cancer Biol Ther. 2021 12 02; 22(10-12):587-597. PMID: 34705606.
      Citations: 5     Fields:    Translation:HumansCells
    8. Naidoo M, Levine F, Gillot T, Orunmuyi AT, Olapade-Olaopa EO, Ali T, Krampis K, Pan C, Dorsaint P, Sboner A, Ogunwobi OO. MicroRNA-1205 Regulation of FRYL in Prostate Cancer. Front Cell Dev Biol. 2021; 9:647485. PMID: 34386489.
    9. Asante-Asamani EO, Pal G, Liu L, Ogunwobi OO. Prostac: A New Composite Score With Potential Predictive Value in Prostate Cancer. Front Oncol. 2021; 11:644665. PMID: 33796469.
    10. Levine F, Ogunwobi OO. Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells. Cancers (Basel). 2021 Mar 02; 13(5). PMID: 33801373.
    11. Beales ILP, Ogunwobi OO. Leptin activates Akt in oesophageal cancer cells via multiple atorvastatin-sensitive small GTPases. Mol Cell Biochem. 2021 Jun; 476(6):2307-2316. PMID: 33582946.
      Citations: 1     Fields:    Translation:HumansCells
    12. Ogunwobi OO, Segura MF. Editorial: PVT1 in Cancer. Front Oncol. 2020; 10:588786. PMID: 33194746.
    13. Ogunwobi OO, Mahmood F, Akingboye A. Biomarkers in Colorectal Cancer: Current Research and Future Prospects. Int J Mol Sci. 2020 Jul 27; 21(15). PMID: 32726923.
      Citations: 54     Fields:    Translation:Humans
    14. Pal G, Di L, Orunmuyi A, Olapade-Olaopa EO, Qiu W, Ogunwobi OO. Population Differentiation at the PVT1 Gene Locus: Implications for Prostate Cancer. G3 (Bethesda). 2020 07 07; 10(7):2257-2264. PMID: 32358016.
      Citations: 4     Fields:    Translation:Humans
    15. Huaman J, Ogunwobi OO. Circulating Tumor Cell Migration Requires Fibronectin Acting through Integrin B1 or SLUG. Cells. 2020 07 01; 9(7). PMID: 32630254.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    16. Shireman TI, Adia AC, Tan Y, Zhu L, Rhee J, Ogunwobi OO, Ma GX. Online versus in-person training of community health workers to enhance hepatitis B virus screening among Korean Americans: Evaluating cost & outcomes. Prev Med Rep. 2020 Sep; 19:101131. PMID: 32518742.
    17. Onagoruwa OT, Pal G, Ochu C, Ogunwobi OO. Oncogenic Role of PVT1 and Therapeutic Implications. Front Oncol. 2020; 10:17. PMID: 32117705.
    18. Agrawal R, Chen M, Bukhari Z, Ogunwobi OO, Haseeb MA, Martello LA. EZH2 Downregulation Augments the Effect of Irradiation in Reducing Pancreatic Cancer Cell Proliferation in vitro. Ann Clin Lab Sci. 2020 Jan; 50(1):45-56. PMID: 32161011.
      Citations:    Fields:    Translation:HumansCells
    19. Pal G, Ogunwobi OO. Copy number-based quantification assay for non-invasive detection of PVT1-derived transcripts. PLoS One. 2019; 14(12):e0226620. PMID: 31877167.
      Citations: 3     Fields:    Translation:HumansCells
    20. Harricharran T, Ogunwobi OO. Oxytocin and oxytocin receptor alterations, decreased survival, and increased chemoresistance in patients with pancreatic cancer. Hepatobiliary Pancreat Dis Int. 2020 Apr; 19(2):175-180. PMID: 31919036.
      Citations: 2     Fields:    Translation:HumansCells
    21. Ogunwobi OO, Dibba O, Zhu L, Ilboudo A, Tan Y, Fraser MA, Ma GX. Hepatitis B Virus Screening and Vaccination in First-generation African Immigrants: A Pilot Study. J Community Health. 2019 12; 44(6):1037-1043. PMID: 31123877.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    22. Pal G, Huaman J, Levine F, Orunmuyi A, Olapade-Olaopa EO, Onagoruwa OT, Ogunwobi OO. Long Noncoding RNA from PVT1 Exon 9 Is Overexpressed in Prostate Cancer and Induces Malignant Transformation and Castration Resistance in Prostate Epithelial Cells. Genes (Basel). 2019 11 22; 10(12). PMID: 31766781.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    23. Zambrano CN, Johnson C, Lu W, Beeber M, Panitz A, Wyka K, Ibrahim S, Fraser M, Bhimla A, Tan Y, Navder K, Yeh MC, Ma GX, Ogunwobi OO. Dietary Behavior and Urinary Gallic Acid Concentrations in Older Minority Residents of East Harlem, New York City. J Racial Ethn Health Disparities. 2020 04; 7(2):217-223. PMID: 31677077.
      Citations: 1     Fields:    Translation:Humans
    24. Anand P, Filipenko P, Huaman J, Lyudmer M, Hossain M, Santamaria C, Huang K, Ogunwobi OO, Holford M. Selective Inhibition of Liver Cancer Cells Using Venom Peptide. Mar Drugs. 2019 Oct 17; 17(10). PMID: 31627357.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    25. Ogunwobi OO, Kumar A. Chemoresistance Mediated by ceRNA Networks Associated With the PVT1 Locus. Front Oncol. 2019; 9:834. PMID: 31508377.
    26. Harricharran T, Ogunwobi OO. Emergence of neural regulatory mechanisms in carcinogenesis. World J Clin Oncol. 2019 Aug 24; 10(8):279-282. PMID: 31528543.
    27. Huaman J, Naidoo M, Zang X, Ogunwobi OO. Fibronectin Regulation of Integrin B1 and SLUG in Circulating Tumor Cells. Cells. 2019 06 20; 8(6). PMID: 31226820.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    28. Harricharran T, Ogunwobi OO. Oxytocin receptor genetic alterations in hepatocellular carcinoma. SN Compr Clin Med. 2019 Jul; 1(7):523-526. PMID: 32856014.
    29. Derderian C, Orunmuyi AT, Olapade-Olaopa EO, Ogunwobi OO. PVT1 Signaling Is a Mediator of Cancer Progression. Front Oncol. 2019; 9:502. PMID: 31249809.
    31. Ogunwobi OO, Harricharran T, Huaman J, Galuza A, Odumuwagun O, Tan Y, Ma GX, Nguyen MT. Mechanisms of hepatocellular carcinoma progression. World J Gastroenterol. 2019 May 21; 25(19):2279-2293. PMID: 31148900.
      Citations: 62     Fields:    Translation:Humans
    32. Ogunwobi OO, Ma GX. SPEECH: Synergistic Partnership for Enhancing Equity in Cancer Health. Cancer Health Disparities. 2020; 4:e1-e5. PMID: 34041449.
    33. Gao C, Xiao G, Piersigilli A, Gou J, Ogunwobi O, Bargonetti J. Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells. Breast Cancer Res. 2019 01 14; 21(1):5. PMID: 30642351.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    34. Lerman B, Harricharran T, Ogunwobi OO. Oxytocin and cancer: An emerging link. World J Clin Oncol. 2018 Sep 14; 9(5):74-82. PMID: 30254962.
    35. Lee M, Zhu L, Wang MQ, Wei Z, Tan Y, Nguyen MT, Ogunwobi OO, Ma GX. Psychosocial Predictors of HBV Screening Behavior among Vietnamese Americans. Am J Health Behav. 2017 Sep 01; 41(5):561-570. PMID: 28760178.
      Citations: 7     Fields:    Translation:Humans
    36. Luu HN, Lin HY, S?rensen KD, Ogunwobi OO, Kumar N, Chornokur G, Phelan C, Jones D, Kidd L, Batra J, Yamoah K, Berglund A, Rounbehler RJ, Yang M, Lee SH, Kang N, Kim SJ, Park JY, Di Pietro G. miRNAs associated with prostate cancer risk and progression. BMC Urol. 2017 Mar 20; 17(1):18. PMID: 28320379.
      Citations: 42     Fields:    Translation:Humans
    37. Das DK, Ogunwobi OO. A novel microRNA-1207-3p/FNDC1/FN1/AR regulatory pathway in prostate cancer. RNA Dis. 2017; 4(1). PMID: 28251177.
    38. Das DK, Ali T, Krampis K, Ogunwobi OO. Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis. Data Brief. 2017 Apr; 11:131-135. PMID: 28210664.
    39. Das DK, Naidoo M, Ilboudo A, Park JY, Ali T, Krampis K, Robinson BD, Osborne JR, Ogunwobi OO. miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin. Exp Cell Res. 2016 Nov 01; 348(2):190-200. PMID: 27693493.
      Citations: 28     Fields:    Translation:HumansCells
    40. Spratt DE, Chan T, Waldron L, Speers C, Feng FY, Ogunwobi OO, Osborne JR. Racial/Ethnic Disparities in Genomic Sequencing. JAMA Oncol. 2016 Aug 01; 2(8):1070-4. PMID: 27366979.
      Citations: 125     Fields:    Translation:Humans
    41. Das DK, Osborne JR, Lin HY, Park JY, Ogunwobi OO. miR-1207-3p Is a Novel Prognostic Biomarker of Prostate Cancer. Transl Oncol. 2016 Jun; 9(3):236-41. PMID: 27267842.
    42. Ilboudo A, Chouhan J, McNeil BK, Osborne JR, Ogunwobi OO. PVT1 Exon 9: A Potential Biomarker of Aggressive Prostate Cancer? Int J Environ Res Public Health. 2015 Dec 22; 13(1):ijerph13010012. PMID: 26703666.
      Citations: 22     Fields:    Translation:HumansCells
    43. Das DK, Durojaiye V, Ilboudo A, Naidoo MK, Ogunwobi O. A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis. J Vis Exp. 2015 Oct 24; (105):e52858. PMID: 26555484.
      Citations: 1     Fields:    Translation:Animals
    44. Das DK, Naidoo MK, Ilboudo A, DuBois P, Durojaiye V, Liu C, Ogunwobi OO. Isolation and Propagation of Circulating Tumor Cells from a Mouse Cancer Model. J Vis Exp. 2015 Oct 09; (104). PMID: 26484891.
      Citations: 3     Fields:    Translation:AnimalsCells
    45. George TJ, Ogunwobi OO, Sheng W, Fan ZH, Liu C. "Tissue is the issue": circulating tumor cells in pancreatic cancer. J Gastrointest Cancer. 2014 Dec; 45 Suppl 1:222-5. PMID: 25012516.
      Citations: 5     Fields:    Translation:HumansCells
    46. Sheng W, Ogunwobi OO, Chen T, Zhang J, George TJ, Liu C, Fan ZH. Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip. Lab Chip. 2014 Jan 07; 14(1):89-98. PMID: 24220648.
      Citations: 104     Fields:    Translation:HumansCells
    47. Beales ILP, Garcia-Morales C, Ogunwobi OO, Mutungi G. Adiponectin inhibits leptin-induced oncogenic signalling in oesophageal cancer cells by activation of PTP1B. Mol Cell Endocrinol. 2014 Jan 25; 382(1):150-158. PMID: 23994026.
      Citations: 26     Fields:    Translation:HumansCells
    48. Ogunwobi OO, Puszyk W, Dong HJ, Liu C. Epigenetic upregulation of HGF and c-Met drives metastasis in hepatocellular carcinoma. PLoS One. 2013; 8(5):e63765. PMID: 23723997.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    49. Zhao X, Tian C, Puszyk WM, Ogunwobi OO, Cao M, Wang T, Cabrera R, Nelson DR, Liu C. OPA1 downregulation is involved in sorafenib-induced apoptosis in hepatocellular carcinoma. Lab Invest. 2013 Jan; 93(1):8-19. PMID: 23108376.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    50. Ogunwobi OO, Wang T, Zhang L, Liu C. Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma. J Gastroenterol Hepatol. 2012 Mar; 27(3):566-78. PMID: 22097969.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    51. Ogunwobi OO, Liu C. Therapeutic and prognostic importance of epithelial-mesenchymal transition in liver cancers: insights from experimental models. Crit Rev Oncol Hematol. 2012 Sep; 83(3):319-28. PMID: 22178416.
      Citations: 19     Fields:    Translation:HumansAnimals
    52. Zhao X, Ogunwobi OO, Liu C. Survivin inhibition is critical for Bcl-2 inhibitor-induced apoptosis in hepatocellular carcinoma cells. PLoS One. 2011; 6(8):e21980. PMID: 21829603.
      Citations: 22     Fields:    Translation:HumansCells
    53. Ogunwobi OO, Liu C. Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways. Clin Exp Metastasis. 2011 Dec; 28(8):721-31. PMID: 21744257.
      Citations: 65     Fields:    Translation:AnimalsCells
    54. Beales IL, Ogunwobi OO. Microsomal prostaglandin E synthase-1 inhibition blocks proliferation and enhances apoptosis in oesophageal adenocarcinoma cells without affecting endothelial prostacyclin production. Int J Cancer. 2010 May 01; 126(9):2247-55. PMID: 19739114.
      Citations: 14     Fields:    Translation:HumansCells
    55. Sirica AE, Dumur CI, Campbell DJ, Almenara JA, Ogunwobi OO, Dewitt JL. Intrahepatic cholangiocarcinoma progression: prognostic factors and basic mechanisms. Clin Gastroenterol Hepatol. 2009 Nov; 7(11 Suppl):S68-78. PMID: 19896103.
      Citations: 40     Fields:    Translation:HumansAnimals
    56. Beales IL, Ogunwobi OO. Glycine-extended gastrin inhibits apoptosis in Barrett's oesophageal and oesophageal adenocarcinoma cells through JAK2/STAT3 activation. J Mol Endocrinol. 2009 Apr; 42(4):305-18. PMID: 19153190.
      Citations: 12     Fields:    Translation:HumansCells
    57. Ogunwobi OO, Beales IL. Glycine-extended gastrin stimulates proliferation via JAK2- and Akt-dependent NF-kappaB activation in Barrett's oesophageal adenocarcinoma cells. Mol Cell Endocrinol. 2008 Dec 16; 296(1-2):94-102. PMID: 18771702.
      Citations: 12     Fields:    Translation:HumansCells
    58. Ogunwobi OO, Beales IL. Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. Am J Gastroenterol. 2008 Apr; 103(4):825-37. PMID: 18371146.
      Citations: 64     Fields:    Translation:AnimalsCells
    59. Ogunwobi OO, Beales IL. Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation. Mol Cell Endocrinol. 2008 Mar 26; 285(1-2):43-50. PMID: 18313838.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    60. Ogunwobi OO, Beales IL. Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor. Br J Biomed Sci. 2008; 65(3):121-7. PMID: 18986098.
      Citations: 21     Fields:    Translation:HumansCells
    61. Beales IL, Ogunwobi O, Cameron E, El-Amin K, Mutungi G, Wilkinson M. Activation of Akt is increased in the dysplasia-carcinoma sequence in Barrett's oesophagus and contributes to increased proliferation and inhibition of apoptosis: a histopathological and functional study. BMC Cancer. 2007 Jun 08; 7:97. PMID: 17559672.
      Citations: 21     Fields:    Translation:HumansCells
    62. Beales IL, Ogunwobi OO. Leptin synergistically enhances the anti-apoptotic and growth-promoting effects of acid in OE33 oesophageal adenocarcinoma cells in culture. Mol Cell Endocrinol. 2007 Aug 15; 274(1-2):60-8. PMID: 17618045.
      Citations: 20     Fields:    Translation:HumansCells
    63. Ogunwobi OO, Beales IL. Cyclo-oxygenase-independent inhibition of apoptosis and stimulation of proliferation by leptin in human colon cancer cells. Dig Dis Sci. 2007 Aug; 52(8):1934-45. PMID: 17406816.
      Citations: 10     Fields:    Translation:HumansCells
    64. Ogunwobi OO, Beales IL. The role of adiponectin in colitis. Gastroenterology. 2007 Mar; 132(3):1199-200; author reply 1200-1. PMID: 17383446.
      Citations:    Fields:    Translation:AnimalsCells
    65. Beales IL, Ogunwobi O. Adipokines and gastrointestinal disease. Aliment Pharmacol Ther. 2006 Oct 01; 24(7):1127-8; author reply 1129-31. PMID: 16984507.
      Citations:    Fields:    Translation:Humans
    66. Ogunwobi OO, Beales IL. The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt. Int J Colorectal Dis. 2007 Apr; 22(4):401-9. PMID: 16912864.
      Citations: 41     Fields:    Translation:HumansCells
    67. Ogunwobi O, Mutungi G, Beales IL. Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activation. Endocrinology. 2006 Sep; 147(9):4505-16. PMID: 16740977.
      Citations: 71     Fields:    Translation:HumansCells
    68. Ogunwobi OO, Beales IL. Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regul Pept. 2006 May 15; 134(2-3):105-13. PMID: 16529829.
      Citations: 47     Fields:    Translation:HumansCells
    69. Beales IL, Ogunwobi O. Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways. Mol Cell Endocrinol. 2006 Mar 09; 247(1-2):140-9. PMID: 16442704.
      Citations: 14     Fields:    Translation:HumansCells
    70. Ogunwobi OO, Beales IL. Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways. Regul Pept. 2006 Mar 15; 134(1):1-8. PMID: 16169610.
      Citations: 12     Fields:    Translation:HumansCells
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