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Olorunseun Ogunwobi

Faculty RankAssociate Professor
InstitutionHunter College, CUNY
DepartmentBiological Sciences
Address695 Park Avenue
Room 932HN
New York NY 10065
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    2017Carnegie African Diaspora Fellowship, Carnegie Corporation of New York

    Collapse Overview 
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    The overall goal of our laboratory is to elucidate the mechanisms of metastasis in solid organ cancers. Ongoing studies include examination of the role of circulating tumor cell biology and epigenetics in the metastasis of solid organ cancers. Also, our laboratory is investigating the biological mechanisms underlying the racial disparities in specific solid organ cancers. The cancer models we are currently focused on are hepatocellular carcinoma, pancreatic cancer, colon cancer, and prostate cancer.
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    U54CA221704     (OGUNWOBI, OLORUNSEUN O)Sep 18, 2018 - Aug 31, 2023
    (2/2) TUFCCC/HC Regional Comprehensive Cancer Health Disparity Partnership
    Role: Principal Investigator

    U54CA221705     (MA, GRACE X.)Sep 19, 2018 - Aug 31, 2023
    1/2 TUFCCC/HC Regional Comprehensive Cancer Health Disparity Partnership
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ogunwobi OO, Segura MF. Editorial: PVT1 in Cancer. Front Oncol. 2020; 10:588786. PMID: 33194746.
    2. Ogunwobi OO, Mahmood F, Akingboye A. Biomarkers in Colorectal Cancer: Current Research and Future Prospects. Int J Mol Sci. 2020 Jul 27; 21(15). PMID: 32726923.
      Citations: 1     Fields:    
    3. Pal G, Di L, Orunmuyi A, Olapade-Olaopa EO, Qiu W, Ogunwobi OO. Population Differentiation at the PVT1 Gene Locus: Implications for Prostate Cancer. G3 (Bethesda). 2020 07 07; 10(7):2257-2264. PMID: 32358016.
      Citations: 1     Fields:    
    4. Huaman J, Ogunwobi OO. Circulating Tumor Cell Migration Requires Fibronectin Acting through Integrin B1 or SLUG. Cells. 2020 07 01; 9(7). PMID: 32630254.
      Citations:    Fields:    
    5. Shireman TI, Adia AC, Tan Y, Zhu L, Rhee J, Ogunwobi OO, Ma GX. Online versus in-person training of community health workers to enhance hepatitis B virus screening among Korean Americans: Evaluating cost & outcomes. Prev Med Rep. 2020 Sep; 19:101131. PMID: 32518742.
    6. Onagoruwa OT, Pal G, Ochu C, Ogunwobi OO. Oncogenic Role of PVT1 and Therapeutic Implications. Front Oncol. 2020; 10:17. PMID: 32117705.
    7. Agrawal R, Chen M, Bukhari Z, Ogunwobi OO, Haseeb MA, Martello LA. EZH2 Downregulation Augments the Effect of Irradiation in Reducing Pancreatic Cancer Cell Proliferation in vitro. Ann Clin Lab Sci. 2020 Jan; 50(1):45-56. PMID: 32161011.
      Citations:    Fields:    Translation:HumansCells
    8. Pal G, Ogunwobi OO. Copy number-based quantification assay for non-invasive detection of PVT1-derived transcripts. PLoS One. 2019; 14(12):e0226620. PMID: 31877167.
      Citations: 2     Fields:    Translation:HumansCells
    9. Harricharran T, Ogunwobi OO. Oxytocin and oxytocin receptor alterations, decreased survival, and increased chemoresistance in patients with pancreatic cancer. Hepatobiliary Pancreat Dis Int. 2020 Apr; 19(2):175-180. PMID: 31919036.
      Citations:    Fields:    
    10. Ogunwobi OO, Dibba O, Zhu L, Ilboudo A, Tan Y, Fraser MA, Ma GX. Hepatitis B Virus Screening and Vaccination in First-generation African Immigrants: A Pilot Study. J Community Health. 2019 12; 44(6):1037-1043. PMID: 31123877.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    11. Pal G, Huaman J, Levine F, Orunmuyi A, Olapade-Olaopa EO, Onagoruwa OT, Ogunwobi OO. Long Noncoding RNA from PVT1 Exon 9 Is Overexpressed in Prostate Cancer and Induces Malignant Transformation and Castration Resistance in Prostate Epithelial Cells. Genes (Basel). 2019 11 22; 10(12). PMID: 31766781.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    12. Zambrano CN, Johnson C, Lu W, Beeber M, Panitz A, Wyka K, Ibrahim S, Fraser M, Bhimla A, Tan Y, Navder K, Yeh MC, Ma GX, Ogunwobi OO. Dietary Behavior and Urinary Gallic Acid Concentrations in Older Minority Residents of East Harlem, New York City. J Racial Ethn Health Disparities. 2020 04; 7(2):217-223. PMID: 31677077.
      Citations:    Fields:    
    13. Anand P, Filipenko P, Huaman J, Lyudmer M, Hossain M, Santamaria C, Huang K, Ogunwobi OO, Holford M. Selective Inhibition of Liver Cancer Cells Using Venom Peptide. Mar Drugs. 2019 Oct 17; 17(10). PMID: 31627357.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    14. Ogunwobi OO, Kumar A. Chemoresistance Mediated by ceRNA Networks Associated With the PVT1 Locus. Front Oncol. 2019; 9:834. PMID: 31508377.
    15. Harricharran T, Ogunwobi OO. Emergence of neural regulatory mechanisms in carcinogenesis. World J Clin Oncol. 2019 Aug 24; 10(8):279-282. PMID: 31528543.
    16. Huaman J, Naidoo M, Zang X, Ogunwobi OO. Fibronectin Regulation of Integrin B1 and SLUG in Circulating Tumor Cells. Cells. 2019 06 20; 8(6). PMID: 31226820.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    17. Harricharran T, Ogunwobi OO. Oxytocin receptor genetic alterations in hepatocellular carcinoma. SN Compr Clin Med. 2019 Jul; 1(7):523-526. PMID: 32856014.
    18. Derderian C, Orunmuyi AT, Olapade-Olaopa EO, Ogunwobi OO. PVT1 Signaling Is a Mediator of Cancer Progression. Front Oncol. 2019; 9:502. PMID: 31249809.
    20. Ogunwobi OO, Harricharran T, Huaman J, Galuza A, Odumuwagun O, Tan Y, Ma GX, Nguyen MT. Mechanisms of hepatocellular carcinoma progression. World J Gastroenterol. 2019 May 21; 25(19):2279-2293. PMID: 31148900.
      Citations: 24     Fields:    Translation:Humans
    21. Gao C, Xiao G, Piersigilli A, Gou J, Ogunwobi O, Bargonetti J. Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells. Breast Cancer Res. 2019 01 14; 21(1):5. PMID: 30642351.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    22. Lerman B, Harricharran T, Ogunwobi OO. Oxytocin and cancer: An emerging link. World J Clin Oncol. 2018 Sep 14; 9(5):74-82. PMID: 30254962.
    23. Lee M, Zhu L, Wang MQ, Wei Z, Tan Y, Nguyen MT, Ogunwobi OO, Ma GX. Psychosocial Predictors of HBV Screening Behavior among Vietnamese Americans. Am J Health Behav. 2017 Sep 01; 41(5):561-570. PMID: 28760178.
      Citations: 2     Fields:    Translation:Humans
    24. Luu HN, Lin HY, Sørensen KD, Ogunwobi OO, Kumar N, Chornokur G, Phelan C, Jones D, Kidd L, Batra J, Yamoah K, Berglund A, Rounbehler RJ, Yang M, Lee SH, Kang N, Kim SJ, Park JY, Di Pietro G. miRNAs associated with prostate cancer risk and progression. BMC Urol. 2017 Mar 20; 17(1):18. PMID: 28320379.
      Citations: 28     Fields:    Translation:Humans
    25. Das DK, Ogunwobi OO. A novel microRNA-1207-3p/FNDC1/FN1/AR regulatory pathway in prostate cancer. RNA Dis. 2017; 4(1). PMID: 28251177.
    26. Das DK, Ali T, Krampis K, Ogunwobi OO. Fibronectin and androgen receptor expression data in prostate cancer obtained from a RNA-sequencing bioinformatics analysis. Data Brief. 2017 Apr; 11:131-135. PMID: 28210664.
    27. Das DK, Naidoo M, Ilboudo A, Park JY, Ali T, Krampis K, Robinson BD, Osborne JR, Ogunwobi OO. miR-1207-3p regulates the androgen receptor in prostate cancer via FNDC1/fibronectin. Exp Cell Res. 2016 Nov 01; 348(2):190-200. PMID: 27693493.
      Citations: 19     Fields:    Translation:HumansCells
    28. Spratt DE, Chan T, Waldron L, Speers C, Feng FY, Ogunwobi OO, Osborne JR. Racial/Ethnic Disparities in Genomic Sequencing. JAMA Oncol. 2016 Aug 01; 2(8):1070-4. PMID: 27366979.
      Citations: 60     Fields:    Translation:Humans
    29. Das DK, Osborne JR, Lin HY, Park JY, Ogunwobi OO. miR-1207-3p Is a Novel Prognostic Biomarker of Prostate Cancer. Transl Oncol. 2016 Jun; 9(3):236-41. PMID: 27267842.
    30. Ilboudo A, Chouhan J, McNeil BK, Osborne JR, Ogunwobi OO. PVT1 Exon 9: A Potential Biomarker of Aggressive Prostate Cancer? Int J Environ Res Public Health. 2015 Dec 22; 13(1):ijerph13010012. PMID: 26703666.
      Citations: 11     Fields:    Translation:HumansCells
    31. Das DK, Durojaiye V, Ilboudo A, Naidoo MK, Ogunwobi O. A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis. J Vis Exp. 2015 Oct 24; (105):e52858. PMID: 26555484.
      Citations:    Fields:    Translation:Animals
    32. Das DK, Naidoo MK, Ilboudo A, DuBois P, Durojaiye V, Liu C, Ogunwobi OO. Isolation and Propagation of Circulating Tumor Cells from a Mouse Cancer Model. J Vis Exp. 2015 Oct 09; (104). PMID: 26484891.
      Citations: 1     Fields:    Translation:AnimalsCells
    33. George TJ, Ogunwobi OO, Sheng W, Fan ZH, Liu C. "Tissue is the issue": circulating tumor cells in pancreatic cancer. J Gastrointest Cancer. 2014 Dec; 45 Suppl 1:222-5. PMID: 25012516.
      Citations: 4     Fields:    Translation:HumansCells
    34. Sheng W, Ogunwobi OO, Chen T, Zhang J, George TJ, Liu C, Fan ZH. Capture, release and culture of circulating tumor cells from pancreatic cancer patients using an enhanced mixing chip. Lab Chip. 2014 Jan 07; 14(1):89-98. PMID: 24220648.
      Citations: 75     Fields:    Translation:HumansCells
    35. Beales ILP, Garcia-Morales C, Ogunwobi OO, Mutungi G. Adiponectin inhibits leptin-induced oncogenic signalling in oesophageal cancer cells by activation of PTP1B. Mol Cell Endocrinol. 2014 Jan 25; 382(1):150-158. PMID: 23994026.
      Citations: 17     Fields:    Translation:HumansCells
    36. Ogunwobi OO, Puszyk W, Dong HJ, Liu C. Epigenetic upregulation of HGF and c-Met drives metastasis in hepatocellular carcinoma. PLoS One. 2013; 8(5):e63765. PMID: 23723997.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    37. Zhao X, Tian C, Puszyk WM, Ogunwobi OO, Cao M, Wang T, Cabrera R, Nelson DR, Liu C. OPA1 downregulation is involved in sorafenib-induced apoptosis in hepatocellular carcinoma. Lab Invest. 2013 Jan; 93(1):8-19. PMID: 23108376.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    38. Ogunwobi OO, Wang T, Zhang L, Liu C. Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma. J Gastroenterol Hepatol. 2012 Mar; 27(3):566-78. PMID: 22097969.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    39. Ogunwobi OO, Liu C. Therapeutic and prognostic importance of epithelial-mesenchymal transition in liver cancers: insights from experimental models. Crit Rev Oncol Hematol. 2012 Sep; 83(3):319-28. PMID: 22178416.
      Citations: 19     Fields:    Translation:HumansAnimals
    40. Zhao X, Ogunwobi OO, Liu C. Survivin inhibition is critical for Bcl-2 inhibitor-induced apoptosis in hepatocellular carcinoma cells. PLoS One. 2011; 6(8):e21980. PMID: 21829603.
      Citations: 16     Fields:    Translation:HumansCells
    41. Ogunwobi OO, Liu C. Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways. Clin Exp Metastasis. 2011 Dec; 28(8):721-31. PMID: 21744257.
      Citations: 54     Fields:    Translation:AnimalsCells
    42. Beales IL, Ogunwobi OO. Microsomal prostaglandin E synthase-1 inhibition blocks proliferation and enhances apoptosis in oesophageal adenocarcinoma cells without affecting endothelial prostacyclin production. Int J Cancer. 2010 May 01; 126(9):2247-55. PMID: 19739114.
      Citations: 13     Fields:    Translation:HumansCells
    43. Sirica AE, Dumur CI, Campbell DJ, Almenara JA, Ogunwobi OO, Dewitt JL. Intrahepatic cholangiocarcinoma progression: prognostic factors and basic mechanisms. Clin Gastroenterol Hepatol. 2009 Nov; 7(11 Suppl):S68-78. PMID: 19896103.
      Citations: 31     Fields:    Translation:HumansAnimals
    44. Beales IL, Ogunwobi OO. Glycine-extended gastrin inhibits apoptosis in Barrett's oesophageal and oesophageal adenocarcinoma cells through JAK2/STAT3 activation. J Mol Endocrinol. 2009 Apr; 42(4):305-18. PMID: 19153190.
      Citations: 10     Fields:    Translation:HumansCells
    45. Ogunwobi OO, Beales IL. Glycine-extended gastrin stimulates proliferation via JAK2- and Akt-dependent NF-kappaB activation in Barrett's oesophageal adenocarcinoma cells. Mol Cell Endocrinol. 2008 Dec 16; 296(1-2):94-102. PMID: 18771702.
      Citations: 11     Fields:    Translation:HumansCells
    46. Ogunwobi OO, Beales IL. Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. Am J Gastroenterol. 2008 Apr; 103(4):825-37. PMID: 18371146.
      Citations: 53     Fields:    Translation:AnimalsCells
    47. Ogunwobi OO, Beales IL. Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation. Mol Cell Endocrinol. 2008 Mar 26; 285(1-2):43-50. PMID: 18313838.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    48. Ogunwobi OO, Beales IL. Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor. Br J Biomed Sci. 2008; 65(3):121-7. PMID: 18986098.
      Citations: 17     Fields:    Translation:HumansCells
    49. Beales IL, Ogunwobi O, Cameron E, El-Amin K, Mutungi G, Wilkinson M. Activation of Akt is increased in the dysplasia-carcinoma sequence in Barrett's oesophagus and contributes to increased proliferation and inhibition of apoptosis: a histopathological and functional study. BMC Cancer. 2007 Jun 08; 7:97. PMID: 17559672.
      Citations: 19     Fields:    Translation:HumansCells
    50. Beales IL, Ogunwobi OO. Leptin synergistically enhances the anti-apoptotic and growth-promoting effects of acid in OE33 oesophageal adenocarcinoma cells in culture. Mol Cell Endocrinol. 2007 Aug 15; 274(1-2):60-8. PMID: 17618045.
      Citations: 18     Fields:    Translation:HumansCells
    51. Ogunwobi OO, Beales IL. Cyclo-oxygenase-independent inhibition of apoptosis and stimulation of proliferation by leptin in human colon cancer cells. Dig Dis Sci. 2007 Aug; 52(8):1934-45. PMID: 17406816.
      Citations: 9     Fields:    Translation:HumansCells
    52. Ogunwobi OO, Beales IL. The role of adiponectin in colitis. Gastroenterology. 2007 Mar; 132(3):1199-200; author reply 1200-1. PMID: 17383446.
      Citations:    Fields:    Translation:AnimalsCells
    53. Beales IL, Ogunwobi O. Adipokines and gastrointestinal disease. Aliment Pharmacol Ther. 2006 Oct 01; 24(7):1127-8; author reply 1129-31. PMID: 16984507.
      Citations:    Fields:    Translation:Humans
    54. Ogunwobi OO, Beales IL. The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt. Int J Colorectal Dis. 2007 Apr; 22(4):401-9. PMID: 16912864.
      Citations: 37     Fields:    Translation:HumansCells
    55. Ogunwobi O, Mutungi G, Beales IL. Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated transactivation of the epidermal growth factor receptor and c-Jun NH2-terminal kinase activation. Endocrinology. 2006 Sep; 147(9):4505-16. PMID: 16740977.
      Citations: 65     Fields:    Translation:HumansCells
    56. Ogunwobi OO, Beales IL. Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regul Pept. 2006 May 15; 134(2-3):105-13. PMID: 16529829.
      Citations: 38     Fields:    Translation:HumansCells
    57. Beales IL, Ogunwobi O. Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways. Mol Cell Endocrinol. 2006 Mar 09; 247(1-2):140-9. PMID: 16442704.
      Citations: 12     Fields:    Translation:HumansCells
    58. Ogunwobi OO, Beales IL. Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways. Regul Pept. 2006 Mar 15; 134(1):1-8. PMID: 16169610.
      Citations: 12     Fields:    Translation:HumansCells
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