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Laurel A. Eckhardt

TitleHasselbach Professor of Biology
InstitutionHunter College, CUNY
DepartmentBiological Sciences
AddressRoom 927 HN, Hunter College, CUNY
695 Park Avenue
New York NY 10065
Phone(212) 772-5237
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Peng C, Eckhardt LA. Role of the Igh intronic enhancer E? in clonal selection at the pre-B to immature B cell transition. J Immunol. 2013 Oct 15; 191(8):4399-411. PMID: 24058175.
      Citations: 6     Fields:    Translation:AnimalsCells
    2. Yan Y, Pieretti J, Ju Z, Wei S, Christin JR, Bah F, Birshtein BK, Eckhardt LA. Homologous elements hs3a and hs3b in the 3' regulatory region of the murine immunoglobulin heavy chain (Igh) locus are both dispensable for class-switch recombination. J Biol Chem. 2011 Aug 05; 286(31):27123-31. PMID: 21673112.
      Citations: 10     Fields:    Translation:AnimalsCells
    3. Li F, Yan Y, Pieretti J, Feldman DA, Eckhardt LA. Comparison of identical and functional Igh alleles reveals a nonessential role for E? in somatic hypermutation and class-switch recombination. J Immunol. 2010 Nov 15; 185(10):6049-57. PMID: 20937850.
      Citations: 11     Fields:    Translation:AnimalsCells
    4. Li F, Eckhardt LA. A role for the IgH intronic enhancer E mu in enforcing allelic exclusion. J Exp Med. 2009 Jan 16; 206(1):153-67. PMID: 19114667.
      Citations: 13     Fields:    Translation:AnimalsCells
    5. Yan Y, Park SS, Janz S, Eckhardt LA. In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 3' regulatory region induces MYC expression at the immature stage of B cell development. Genes Chromosomes Cancer. 2007 Oct; 46(10):950-9. PMID: 17639584.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    6. Zhang B, Alaie-Petrillo A, Kon M, Li F, Eckhardt LA. Transcription of a productively rearranged Ig VDJC alpha does not require the presence of HS4 in the IgH 3' regulatory region. J Immunol. 2007 May 15; 178(10):6297-306. PMID: 17475858.
      Citations: 4     Fields:    Translation:AnimalsCells
    7. Zhou J, Saleque S, Ermakova O, Sepulveda MA, Yang Q, Eckhardt LA, Schildkraut CL, Birshtein BK. Changes in replication, nuclear location, and expression of the Igh locus after fusion of a pre-B cell line with a T cell line. J Immunol. 2005 Aug 15; 175(4):2317-20. PMID: 16081801.
      Citations: 5     Fields:    Translation:AnimalsCells
    8. Garrett FE, Emelyanov AV, Sepulveda MA, Flanagan P, Volpi S, Li F, Loukinov D, Eckhardt LA, Lobanenkov VV, Birshtein BK. Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites. Mol Cell Biol. 2005 Feb; 25(4):1511-25. PMID: 15684400.
      Citations: 72     Fields:    Translation:AnimalsCells
    9. Salas M, Eckhardt LA. Critical role for the Oct-2/OCA-B partnership in Ig-secreting cells. J Immunol. 2003 Dec 15; 171(12):6589-98. PMID: 14662861.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    10. Sharif MN, Radomska HS, Miller DM, Eckhardt LA. Unique function for carboxyl-terminal domain of Oct-2 in Ig-secreting cells. J Immunol. 2001 Oct 15; 167(8):4421-9. PMID: 11591767.
      Citations: 2     Fields:    Translation:Cells
    11. Shi X, Eckhardt LA. Deletional analyses reveal an essential role for the hs3b/hs4 IgH 3' enhancer pair in an Ig-secreting but not an earlier-stage B cell line. Int Immunol. 2001 Aug; 13(8):1003-12. PMID: 11470770.
      Citations: 17     Fields:    Translation:AnimalsCells
    12. Stevens S, Ong J, Kim U, Eckhardt LA, Roeder RG. Role of OCA-B in 3'-IgH enhancer function. J Immunol. 2000 May 15; 164(10):5306-12. PMID: 10799892.
      Citations: 15     Fields:    Translation:AnimalsCells
    13. Ong J, Stevens S, Roeder RG, Eckhardt LA. 3' IgH enhancer elements shift synergistic interactions during B cell development. J Immunol. 1998 May 15; 160(10):4896-903. PMID: 9590237.
      Citations: 16     Fields:    Translation:AnimalsCells
    14. Hines MD, Radomska HS, Eckhardt LA. Transcription factor effects on chromosome constitution of cell hybrids. Cytogenet Cell Genet. 1998; 83(1-2):64-72. PMID: 9925930.
      Citations:    Fields:    Translation:HumansAnimalsCells
    15. Arulampalam V, Eckhardt L, Pettersson S. The enhancer shift: a model to explain the developmental control of IgH gene expression in B-lineage cells. Immunol Today. 1997 Nov; 18(11):549-54. PMID: 9386352.
      Citations: 5     Fields:    Translation:HumansCells
    16. Choi JK, Shen CP, Radomska HS, Eckhardt LA, Kadesch T. E47 activates the Ig-heavy chain and TdT loci in non-B cells. EMBO J. 1996 Sep 16; 15(18):5014-21. PMID: 8890174.
      Citations: 34     Fields:    Translation:AnimalsCells
    17. Radomska HS, Eckhardt LA. Mammalian cell fusion in an electroporation device. J Immunol Methods. 1995 Dec 27; 188(2):209-17. PMID: 8551049.
      Citations: 5     Fields:    Translation:AnimalsCells
    18. Lieberson R, Ong J, Shi X, Eckhardt LA. Immunoglobulin gene transcription ceases upon deletion of a distant enhancer. EMBO J. 1995 Dec 15; 14(24):6229-38. PMID: 8557042.
      Citations: 26     Fields:    Translation:AnimalsCells
    19. Radomska HS, Hines MD, Eckhardt LA. Role of Oct-2 in immunoglobulin gene silencing. Ann N Y Acad Sci. 1995 Sep 29; 764:148-50. PMID: 7486513.
      Citations:    Fields:    Translation:HumansAnimalsCells
    20. Radomska HS, Shen CP, Kadesch T, Eckhardt LA. Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma x T cell hybrids. Immunity. 1994 Nov; 1(8):623-34. PMID: 7600290.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    21. Lieberman SA, Hines MD, Bergsagel PL, Kuehl WM, Eckhardt LA. Coordinate silencing of myeloma-specific genes in myeloma x T lymphoma hybrids. J Immunol. 1993 Sep 01; 151(5):2588-600. PMID: 8360480.
      Citations: 3     Fields:    Translation:HumansCells
    22. Shen L, Lieberman S, Eckhardt LA. The octamer/mu E4 region of the immunoglobulin heavy-chain enhancer mediates gene repression in myeloma x T-lymphoma hybrids. Mol Cell Biol. 1993 Jun; 13(6):3530-40. PMID: 8497268.
      Citations: 11     Fields:    Translation:AnimalsCells
    23. Bergsagel PL, Timblin CR, Eckhardt L, Laskov R, Kuehl WM. Sequence and expression of a murine cDNA encoding PC326, a novel gene expressed in plasmacytomas but not normal plasma cells. Oncogene. 1992 Oct; 7(10):2059-64. PMID: 1408147.
      Citations: 3     Fields:    Translation:AnimalsCells
    24. Eckhardt LA. Immunoglobulin gene expression only in the right cells at the right time. FASEB J. 1992 May; 6(8):2553-60. PMID: 1592208.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    25. Lieberson R, Giannini SL, Birshtein BK, Eckhardt LA. An enhancer at the 3' end of the mouse immunoglobulin heavy chain locus. Nucleic Acids Res. 1991 Feb 25; 19(4):933-7. PMID: 1901991.
      Citations: 35     Fields:    Translation:AnimalsCells
    26. Porton B, Zaller DM, Lieberson R, Eckhardt LA. Immunoglobulin heavy-chain enhancer is required to maintain transfected gamma 2A gene expression in a pre-B-cell line. Mol Cell Biol. 1990 Mar; 10(3):1076-83. PMID: 2106067.
      Citations: 6     Fields:    Translation:AnimalsCells
    27. Bikoff EK, Eckhardt LA. Presentation of IgG2a antigens to class II-restricted T cells by stably transfected B lymphoma cells. Eur J Immunol. 1989 Oct; 19(10):1903-9. PMID: 2479567.
      Citations: 7     Fields:    Translation:AnimalsCells
    28. Yu H, Porton B, Shen LY, Eckhardt LA. Role of the octamer motif in hybrid cell extinction of immunoglobulin gene expression: extinction is dominant in a two enhancer system. Cell. 1989 Aug 11; 58(3):441-8. PMID: 2547524.
      Citations: 32     Fields:    Translation:AnimalsCells
    29. Zaller DM, Yu H, Eckhardt LA. Genes activated in the presence of an immunoglobulin enhancer or promoter are negatively regulated by a T-lymphoma cell line. Mol Cell Biol. 1988 May; 8(5):1932-9. PMID: 3133550.
      Citations: 15     Fields:    Translation:AnimalsCells
    30. Bikoff EK, Yu H, Eckhardt LA. T cell recognition of endogenous IgG2a expressed in B lymphoma cells. Eur J Immunol. 1988 Mar; 18(3):341-8. PMID: 3258563.
      Citations: 4     Fields:    Translation:AnimalsCells
    31. Yu H, Eckhardt LA. DNA rearrangement causes a high rate of spontaneous mutation at the immunoglobulin heavy-chain locus of a mouse myeloma cell line. Mol Cell Biol. 1986 Dec; 6(12):4228-35. PMID: 3025646.
      Citations: 5     Fields:    Translation:AnimalsCells
    32. Zaller DM, Eckhardt LA. Deletion of a B-cell-specific enhancer affects transfected, but not endogenous, immunoglobulin heavy-chain gene expression. Proc Natl Acad Sci U S A. 1985 Aug; 82(15):5088-92. PMID: 3927296.
      Citations: 30     Fields:    Translation:AnimalsCells
    33. Eckhardt LA, Birshtein BK. Independent immunoglobulin class-switch events occurring in a single myeloma cell line. Mol Cell Biol. 1985 Apr; 5(4):856-68. PMID: 3921826.
      Citations: 32     Fields:    Translation:AnimalsCells
    34. Calza RE, Eckhardt LA, DelGiudice T, Schildkraut CL. Changes in gene position are accompanied by a change in time of replication. Cell. 1984 Mar; 36(3):689-96. PMID: 6421490.
      Citations: 60     Fields:    Translation:AnimalsCells
    35. Stanton LW, Yang JQ, Eckhardt LA, Harris LJ, Birshtein BK, Marcu KB. Products of a reciprocal chromosome translocation involving the c-myc gene in a murine plasmacytoma. Proc Natl Acad Sci U S A. 1984 Feb; 81(3):829-33. PMID: 6322170.
      Citations: 21     Fields:    Translation:AnimalsCells
    36. Tilley SA, Eckhardt LA, Marcu KB, Birshtein BK. Hybrid gamma 2b-gamma 2a genes expressed in myeloma variants: evidence for homologous recombination. Proc Natl Acad Sci U S A. 1983 Nov; 80(22):6967-71. PMID: 6316338.
      Citations: 4     Fields:    Translation:AnimalsCells
    37. Eckhardt LA, Tilley SA, Lang RB, Marcu KB, Birshtein BK. DNA rearrangements in MPC-11 immunoglobulin heavy chain class-switch variants. Proc Natl Acad Sci U S A. 1982 May; 79(9):3006-10. PMID: 6806822.
      Citations: 18     Fields:    Translation:AnimalsCells
    38. Eckhardt LA, Herzenberg LA. Monoclonal antibodies to ThB detect close linkage of Ly-6 and a gene regulating ThB expression. Immunogenetics. 1980; 11(3):275-91. PMID: 6793507.
      Citations: 29     Fields:    Translation:AnimalsCells
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