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Marla J. Berry, Ph.D.

TitleDirector, Pacific Biosciences Research Center
Faculty RankProfessor
InstitutionUniversity of Hawaii
DepartmentPacific Biosciences Research Center, SOEST
AddressUniversity of Hawaii at Manoa
1993 East West Road
Office 215
Honolulu HI 96822
Phone8086921506
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    Other Positions
    TitleGraduate Faculty
    InstitutionUniversity of Hawaii
    DepartmentCTAHR


    Collapse Biography 
    Collapse awards and honors
    1993Women in Endocrinology Award, Endocrine Society
    1998Nutrition Emphasis Week Visiting Professor, University of Missouri, Columbia
    1999American Thyroid Association Van Meter Prize for outstanding contributions to thyroid research
    2001Ruth Pike Lectureship for significant contributions to nutrition research, Pennsylvania State Univ.
    2004Mary Shorb Lecturer, University of Maryland
    2006Scientist of the Year, Achievement Rewards for College Scientists, Honolulu Chapter

    Collapse Overview 
    Collapse overview
    My scientific background includes three decades of experience in biochemistry and cell and molecular biology utilizing cell culture and animal models of human disease, and over two decades studying the functions of antioxidant selenoenzymes in health and disease. During my postdoctoral studies, I was first author on two publications in Nature. The seminal findings described in these publications led to my first NIH R01 grant, an appointment as Assistant Professor at Harvard Medical School, and issue of a US Patent. I remained on the faculty at Harvard Med for 11 years, where I obtained two additional NIH R01s and was promoted to Associate Professor. In 2002, I was recruited by the University of Hawaii, where I was tenured as a full Professor the following year. I have been continuously funded by the NIH since 1993, serving as PI on two R01s beginning in 1997 and three R01s during the period from 2000 to 2007. I served as a Charter Member of the NIH Nutrition Study Section and the Integrative Nutrition and Metabolic Processes Study Section from 2001 through 2005, as well as ad hoc on numerous study sections since 1993. Research in my laboratory currently includes mouse models with alterations in selenium metabolism, affecting antioxidant enzyme expression and resulting in metabolic syndrome and impaired neurological function. We are also investigating epigenetic changes in preeclampsia and have identified hypermethylation and hypomethylation in genes associated with cardiovascular disease-related processes.


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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Seale LA, Torres DJ, Berry MJ, Pitts MW. A role for selenium-dependent GPX1 in SARS-CoV-2 virulence. Am J Clin Nutr. 2020 08 01; 112(2):447-448. PMID: 32592394.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    2. Watanabe LM, Hashimoto AC, Torres DJ, Berry MJ, Seale LA. Effects of selenium supplementation on diet-induced obesity in mice with a disruption of the selenocysteine lyase gene. J Trace Elem Med Biol. 2020 Dec; 62:126596. PMID: 32683228.
      Citations:    Fields:    
    3. Seale LA, Khadka VS, Menor M, Xie G, Watanabe LM, Sasuclark A, Guirguis K, Ha HY, Hashimoto AC, Peplowska K, Tiirikainen M, Jia W, Berry MJ, Deng Y. Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice. Nutrients. 2019 Oct 26; 11(11). PMID: 31717805.
      Citations:    Fields:    Translation:AnimalsCells
    4. Benny P, Yamasato K, Yunits B, Zhu X, Ching T, Garmire LX, Berry MJ, Towner D. Maternal cardiovascular-related single nucleotide polymorphisms, genes, and pathways associated with early-onset preeclampsia. PLoS One. 2019; 14(9):e0222672. PMID: 31557190.
      Citations: 1     Fields:    Translation:Humans
    5. Torres DJ, Pitts MW, Hashimoto AC, Berry MJ. Agrp-Specific Ablation of Scly Protects against Diet-Induced Obesity and Leptin Resistance. Nutrients. 2019 Jul 23; 11(7). PMID: 31340540.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Ha HY, Alfulaij N, Berry MJ, Seale LA. From Selenium Absorption to Selenoprotein Degradation. Biol Trace Elem Res. 2019 Nov; 192(1):26-37. PMID: 31222623.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    7. Kremer PM, Torres DJ, Hashimoto AC, Berry MJ. Disruption of Selenium Handling During Puberty Causes Sex-Specific Neurological Impairments in Mice. Antioxidants (Basel). 2019 Apr 24; 8(4). PMID: 31022880.
      Citations:    
    8. Ofili EO, Tchounwou PB, Fernandez-Repollet E, Yanagihara R, Akintobi TH, Lee JE, Malouhi M, Garner ST, Hayes TT, Baker AR, Dent AL, Abdelrahim M, Rollins L, Chang SP, Sy A, Hernandez BY, Bullard PL, Noel RJ, Shiramizu B, Hedges JR, Berry MJ, Bond VC, Lima MF, Mokuau N, Kirken RA, Cruz-Correa M, Sarpong DF, Vadgama J, Yates C, Kahn SA, Soliman KF, Perry G, Pezzano M, Luciano CA, Barnett ME, Oyekan A, Kumar D, Norris KC. The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research. Ethn Dis. 2019; 29(Suppl 1):135-144. PMID: 30906162.
      Citations: 1     Fields:    Translation:Humans
    9. Seale LA, Ogawa-Wong AN, Berry MJ. SEXUAL DIMORPHISM IN SELENIUM METABOLISM AND SELENOPROTEINS. Free Radic Biol Med. 2018 11 01; 127:198-205. PMID: 29572096.
      Citations: 6     Fields:    Translation:HumansAnimals
    10. Seale LA, Ha HY, Hashimoto AC, Berry MJ. Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism. Free Radic Biol Med. 2018 11 01; 127:182-189. PMID: 29567390.
      Citations: 2     Fields:    Translation:HumansAnimals
    11. Gong T, Torres DJ, Berry MJ, Pitts MW. Hypothalamic redox balance and leptin signaling - Emerging role of selenoproteins. Free Radic Biol Med. 2018 11 01; 127:172-181. PMID: 29518483.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    12. Ogawa-Wong AN, Hashimoto AC, Ha H, Pitts MW, Seale LA, Berry MJ. Sexual Dimorphism in the Selenocysteine Lyase Knockout Mouse. Nutrients. 2018 Jan 31; 10(2). PMID: 29385050.
      Citations: 6     Fields:    Translation:Animals
    13. Berry M, Chen J, Hixon A, Gerschenson M, James N, Jameson D, Lew HL, Lozanoff S, Nichols R, Seifried S, Teshima D, Masaki K, Tam E, Ward B, Ward S. Medical School Hotline: School of Medicine Departments - Year in Review 2017, Part 1. Hawaii J Med Public Health. 2018 01; 77(1):14-16. PMID: 29333336.
      Citations:    Fields:    Translation:Humans
    14. Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. J Alzheimers Dis. 2017; 55(2):749-762. PMID: 27802219.
      Citations: 3     Fields:    Translation:HumansCells
    15. Gladyshev VN, Arnér ES, Berry MJ, Brigelius-Flohé R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Flohé L, Green FR, Guigó R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, Köhrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovic M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y. Selenoprotein Gene Nomenclature. J Biol Chem. 2016 Nov 11; 291(46):24036-24040. PMID: 27645994.
      Citations: 36     Fields:    Translation:Humans
    16. Ogawa-Wong AN, Berry MJ, Seale LA. Selenium and Metabolic Disorders: An Emphasis on Type 2 Diabetes Risk. Nutrients. 2016 Feb 06; 8(2):80. PMID: 26861388.
      Citations: 20     Fields:    Translation:Humans
    17. Pitts MW, Kremer PM, Hashimoto AC, Torres DJ, Byrns CN, Williams CS, Berry MJ. Competition between the Brain and Testes under Selenium-Compromised Conditions: Insight into Sex Differences in Selenium Metabolism and Risk of Neurodevelopmental Disease. J Neurosci. 2015 Nov 18; 35(46):15326-38. PMID: 26586820.
      Citations: 17     Fields:    Translation:Animals
    18. Seale LA, Gilman CL, Hashimoto AC, Ogawa-Wong AN, Berry MJ. Diet-induced obesity in the selenocysteine lyase knockout mouse. Antioxid Redox Signal. 2015 Oct 01; 23(10):761-74. PMID: 26192035.
      Citations: 10     Fields:    Translation:AnimalsCells
    19. Andres MA, Cooke IM, Bellinger FP, Berry MJ, Zaporteza MM, Rueli RH, Barayuga SM, Chang L. Methamphetamine acutely inhibits voltage-gated calcium channels but chronically up-regulates L-type channels. J Neurochem. 2015 Jul; 134(1):56-65. PMID: 25807982.
      Citations: 3     Fields:    Translation:HumansCells
    20. Berry MJ, Astern J, Bellinger F, Brampton C, Cann R, Gerschenson M, Haymer D, James NG, Jameson DM, LeSaux O, Hoffmann PR, Nichols R, Pitts M, Seale L, Seifried S, Stokes AJ, Todorovic C. Medical school hotline: the research mission of the cell and molecular biology department and program at the john a. Burns school of medicine. Hawaii J Med Public Health. 2015 Apr; 74(4):150-3. PMID: 25954603.
      Citations:    Fields:    Translation:Humans
    21. Ching T, Ha J, Song MA, Tiirikainen M, Molnar J, Berry MJ, Towner D, Garmire LX. Genome-scale hypomethylation in the cord blood DNAs associated with early onset preeclampsia. Clin Epigenetics. 2015; 7:21. PMID: 25806090.
      Citations: 14     Fields:    
    22. Gilman CL, Soon R, Sauvage L, Ralston NV, Berry MJ. Umbilical cord blood and placental mercury, selenium and selenoprotein expression in relation to maternal fish consumption. J Trace Elem Med Biol. 2015 Apr; 30:17-24. PMID: 25744505.
      Citations: 1     Fields:    Translation:HumansAnimals
    23. Panee J, Pang X, Munsaka S, Berry MJ, Chang L. Independent and co-morbid HIV infection and Meth use disorders on oxidative stress markers in the cerebrospinal fluid and depressive symptoms. J Neuroimmune Pharmacol. 2015 Mar; 10(1):111-21. PMID: 25575491.
      Citations: 4     Fields:    Translation:Humans
    24. Rueli RH, Parubrub AC, Dewing AS, Hashimoto AC, Bellinger MT, Weeber EJ, Uyehara-Lock JH, White LR, Berry MJ, Bellinger FP. Increased selenoprotein P in choroid plexus and cerebrospinal fluid in Alzheimer's disease brain. J Alzheimers Dis. 2015; 44(2):379-83. PMID: 25298198.
      Citations: 4     Fields:    Translation:Humans
    25. Berry MJ, Cann R, Haymer D, Hoffmann P, Jameson D, LeSaux O, Nichols R, Seifried S, Stokes A, Todorovic C. Medical school hotline: The educational mission of the cell and molecular biology department and program at the John A. Burns School of Medicine. Hawaii J Med Public Health. 2014 Nov; 73(11):362-4. PMID: 25414807.
      Citations:    Fields:    Translation:Humans
    26. Pitts MW, Byrns CN, Ogawa-Wong AN, Kremer P, Berry MJ. Selenoproteins in nervous system development and function. Biol Trace Elem Res. 2014 Dec; 161(3):231-45. PMID: 24974905.
      Citations: 12     Fields:    Translation:HumansAnimals
    27. Seyedali A, Berry MJ. Nonsense-mediated decay factors are involved in the regulation of selenoprotein mRNA levels during selenium deficiency. RNA. 2014 Aug; 20(8):1248-56. PMID: 24947499.
      Citations: 22     Fields:    Translation:HumansCells
    28. Soon R, Dye TD, Ralston NV, Berry MJ, Sauvage LM. Seafood consumption and umbilical cord blood mercury concentrations in a multiethnic maternal and child health cohort. BMC Pregnancy Childbirth. 2014 Jun 18; 14:209. PMID: 24942346.
      Citations: 10     Fields:    Translation:Humans
    29. Ching T, Song MA, Tiirikainen M, Molnar J, Berry M, Towner D, Garmire LX. Genome-wide hypermethylation coupled with promoter hypomethylation in the chorioamniotic membranes of early onset pre-eclampsia. Mol Hum Reprod. 2014 Sep; 20(9):885-904. PMID: 24944161.
      Citations: 15     Fields:    Translation:HumansCells
    30. Seale LA, Gilman CL, Moorman BP, Berry MJ, Grau EG, Seale AP. Effects of acclimation salinity on the expression of selenoproteins in the tilapia, Oreochromis mossambicus. J Trace Elem Med Biol. 2014 Jul; 28(3):284-92. PMID: 24854764.
      Citations: 2     Fields:    Translation:Animals
    31. Kurokawa S, Bellinger FP, Hill KE, Burk RF, Berry MJ. Isoform-specific binding of selenoprotein P to the ß-propeller domain of apolipoprotein E receptor 2 mediates selenium supply. J Biol Chem. 2014 Mar 28; 289(13):9195-207. PMID: 24532792.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    32. Byrns CN, Pitts MW, Gilman CA, Hashimoto AC, Berry MJ. Mice lacking selenoprotein P and selenocysteine lyase exhibit severe neurological dysfunction, neurodegeneration, and audiogenic seizures. J Biol Chem. 2014 Apr 04; 289(14):9662-74. PMID: 24519931.
      Citations: 12     Fields:    Translation:Animals
    33. Raman AV, Pitts MW, Seyedali A, Hashimoto AC, Bellinger FP, Berry MJ. Selenoprotein W expression and regulation in mouse brain and neurons. Brain Behav. 2013 Sep; 3(5):562-74. PMID: 24392277.
      Citations: 2     Fields:    
    34. Pitts MW, Reeves MA, Hashimoto AC, Ogawa A, Kremer P, Seale LA, Berry MJ. Deletion of selenoprotein M leads to obesity without cognitive deficits. J Biol Chem. 2013 Sep 06; 288(36):26121-34. PMID: 23880772.
      Citations: 24     Fields:    Translation:Animals
    35. Pang X, Panee J, Liu X, Berry MJ, Chang SL, Chang L. Regional variations of antioxidant capacity and oxidative stress responses in HIV-1 transgenic rats with and without methamphetamine administration. J Neuroimmune Pharmacol. 2013 Jun; 8(3):691-704. PMID: 23546885.
      Citations: 16     Fields:    Translation:AnimalsCells
    36. Kurokawa S, Berry MJ. Selenium. Role of the essential metalloid in health. Met Ions Life Sci. 2013; 13:499-534. PMID: 24470102.
      Citations: 16     Fields:    Translation:HumansAnimals
    37. Dewing AS, Rueli RH, Robles MJ, Nguyen-Wu ED, Zeyda T, Berry MJ, Bellinger FP. Expression and regulation of mouse selenoprotein P transcript variants differing in non-coding RNA. RNA Biol. 2012 Nov; 9(11):1361-9. PMID: 23064117.
      Citations: 11     Fields:    Translation:AnimalsCells
    38. Seale LA, Hashimoto AC, Kurokawa S, Gilman CL, Seyedali A, Bellinger FP, Raman AV, Berry MJ. Disruption of the selenocysteine lyase-mediated selenium recycling pathway leads to metabolic syndrome in mice. Mol Cell Biol. 2012 Oct; 32(20):4141-54. PMID: 22890841.
      Citations: 27     Fields:    Translation:Animals
    39. Bellinger FP, Raman AV, Rueli RH, Bellinger MT, Dewing AS, Seale LA, Andres MA, Uyehara-Lock JH, White LR, Ross GW, Berry MJ. Changes in selenoprotein P in substantia nigra and putamen in Parkinson's disease. J Parkinsons Dis. 2012; 2(2):115-26. PMID: 23268326.
      Citations: 12     Fields:    Translation:Humans
    40. Higa JK, Liu W, Berry MJ, Panee J. Supplement of bamboo extract lowers serum monocyte chemoattractant protein-1 concentration in mice fed a diet containing a high level of saturated fat. Br J Nutr. 2011 Dec; 106(12):1810-3. PMID: 21736779.
      Citations: 7     Fields:    Translation:Animals
    41. Bellinger FP, Bellinger MT, Seale LA, Takemoto AS, Raman AV, Miki T, Manning-Bog AB, Berry MJ, White LR, Ross GW. Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain. Mol Neurodegener. 2011 Jan 21; 6(1):8. PMID: 21255396.
      Citations: 26     Fields:    
    42. Koide CL, Collier AC, Berry MJ, Panee J. The effect of bamboo extract on hepatic biotransforming enzymes--findings from an obese-diabetic mouse model. J Ethnopharmacol. 2011 Jan 07; 133(1):37-45. PMID: 20832461.
      Citations: 13     Fields:    Translation:Animals
    43. Berry MJ. The Cell and Molecular Biology Department, University of Hawaii at Manoa. Hawaii Med J. 2010 Jun; 69(6):148-9. PMID: 20535689.
      Citations:    Fields:    Translation:Humans
    44. Hoffmann FW, Hashimoto AC, Shafer LA, Dow S, Berry MJ, Hoffmann PR. Dietary selenium modulates activation and differentiation of CD4+ T cells in mice through a mechanism involving cellular free thiols. J Nutr. 2010 Jun; 140(6):1155-61. PMID: 20375261.
      Citations: 43     Fields:    Translation:AnimalsCells
    45. Reeves MA, Bellinger FP, Berry MJ. The neuroprotective functions of selenoprotein M and its role in cytosolic calcium regulation. Antioxid Redox Signal. 2010 Apr 01; 12(7):809-18. PMID: 19769485.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    46. Takemoto AS, Berry MJ, Bellinger FP. Role of selenoprotein P in Alzheimer's disease. Ethn Dis. 2010; 20(1 Suppl 1):S1-92-5. PMID: 20521393.
      Citations: 8     Fields:    Translation:Humans
    47. Stoytcheva ZR, Vladimirov V, Douet V, Stoychev I, Berry MJ. Metal transcription factor-1 regulation via MREs in the transcribed regions of selenoprotein H and other metal-responsive genes. Biochim Biophys Acta. 2010 Mar; 1800(3):416-24. PMID: 19913599.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    48. Bellinger FP, Raman AV, Reeves MA, Berry MJ. Regulation and function of selenoproteins in human disease. Biochem J. 2009 Jul 29; 422(1):11-22. PMID: 19627257.
      Citations: 95     Fields:    Translation:Humans
    49. Squires JE, Davy P, Berry MJ, Allsopp R. Attenuated expression of SECIS binding protein 2 causes loss of telomeric reserve without affecting telomerase. Exp Gerontol. 2009 Sep; 44(9):619-23. PMID: 19563878.
      Citations: 4     Fields:    Translation:HumansCells
    50. Stoytcheva ZR, Berry MJ. Transcriptional regulation of mammalian selenoprotein expression. Biochim Biophys Acta. 2009 Nov; 1790(11):1429-40. PMID: 19465084.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    51. Berry MJ, Ralston NV. Mercury toxicity and the mitigating role of selenium. Ecohealth. 2008 Dec; 5(4):456-9. PMID: 19198945.
      Citations: 26     Fields:    Translation:HumansAnimals
    52. Bellinger FP, He QP, Bellinger MT, Lin Y, Raman AV, White LR, Berry MJ. Association of selenoprotein p with Alzheimer's pathology in human cortex. J Alzheimers Dis. 2008 Nov; 15(3):465-72. PMID: 18997300.
      Citations: 23     Fields:    Translation:HumansCells
    53. Lin Y, Collier AC, Liu W, Berry MJ, Panee J. The inhibitory effect of bamboo extract on the development of 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer. Phytother Res. 2008 Nov; 22(11):1440-5. PMID: 18972584.
      Citations: 5     Fields:    Translation:HumansAnimals
    54. Hoffmann PR, Berry MJ. The influence of selenium on immune responses. Mol Nutr Food Res. 2008 Nov; 52(11):1273-80. PMID: 18384097.
      Citations: 59     Fields:    Translation:Humans
    55. Blauwkamp MN, Yu J, Schin MA, Burke KA, Berry MJ, Carlson BA, Brosius FC, Koenig RJ. Podocyte specific knock out of selenoproteins does not enhance nephropathy in streptozotocin diabetic C57BL/6 mice. BMC Nephrol. 2008 Jul 22; 9:7. PMID: 18647412.
      Citations: 8     Fields:    Translation:AnimalsCells
    56. Panee J, Liu W, Lin Y, Gilman C, Berry MJ. A novel function of bamboo extract in relieving lipotoxicity. Phytother Res. 2008 May; 22(5):675-80. PMID: 18350521.
      Citations: 7     Fields:    Translation:AnimalsCells
    57. Squires JE, Berry MJ. Eukaryotic selenoprotein synthesis: mechanistic insight incorporating new factors and new functions for old factors. IUBMB Life. 2008 Apr; 60(4):232-5. PMID: 18344183.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    58. Castellano S, Gladyshev VN, Guigó R, Berry MJ. SelenoDB 1.0 : a database of selenoprotein genes, proteins and SECIS elements. Nucleic Acids Res. 2008 Jan; 36(Database issue):D332-8. PMID: 18174224.
      Citations: 16     Fields:    Translation:Humans
    59. Xu XM, Carlson BA, Zhang Y, Mix H, Kryukov GV, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL. New developments in selenium biochemistry: selenocysteine biosynthesis in eukaryotes and archaea. Biol Trace Elem Res. 2007 Dec; 119(3):234-41. PMID: 17916946.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    60. Squires JE, Stoytchev I, Forry EP, Berry MJ. SBP2 binding affinity is a major determinant in differential selenoprotein mRNA translation and sensitivity to nonsense-mediated decay. Mol Cell Biol. 2007 Nov; 27(22):7848-55. PMID: 17846120.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    61. Hoffmann PR, Jourdan-Le Saux C, Hoffmann FW, Chang PS, Bollt O, He Q, Tam EK, Berry MJ. A role for dietary selenium and selenoproteins in allergic airway inflammation. J Immunol. 2007 Sep 01; 179(5):3258-67. PMID: 17709542.
      Citations: 24     Fields:    Translation:AnimalsCells
    62. Hoffmann PR, Gurary A, Hoffmann FW, Jourdan-Le Saux C, Teeters K, Hashimoto AC, Tam EK, Berry MJ. A new approach for analyzing cellular infiltration during allergic airway inflammation. J Immunol Methods. 2007 Dec 01; 328(1-2):21-33. PMID: 17825315.
      Citations: 7     Fields:    Translation:AnimalsCells
    63. Panee J, Liu W, Nakamura K, Berry MJ. The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation. Int J Biol Sci. 2007 Jul 13; 3(5):335-41. PMID: 17657281.
      Citations: 16     Fields:    Translation:AnimalsCells
    64. Hoffmann PR, Höge SC, Li PA, Hoffmann FW, Hashimoto AC, Berry MJ. The selenoproteome exhibits widely varying, tissue-specific dependence on selenoprotein P for selenium supply. Nucleic Acids Res. 2007; 35(12):3963-73. PMID: 17553827.
      Citations: 40     Fields:    Translation:Animals
    65. Panee J, Stoytcheva ZR, Liu W, Berry MJ. Selenoprotein H is a redox-sensing high mobility group family DNA-binding protein that up-regulates genes involved in glutathione synthesis and phase II detoxification. J Biol Chem. 2007 Aug 17; 282(33):23759-65. PMID: 17526492.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    66. Morozova N, Khrapko K, Panee J, Liu W, Harney JW, Berry MJ. Glutathione depletion in hippocampal cells increases levels of H and L ferritin and glutathione S-transferase mRNAs. Genes Cells. 2007 May; 12(5):561-7. PMID: 17535247.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    67. Ben Jilani KE, Panee J, He Q, Berry MJ, Li PA. Overexpression of selenoprotein H reduces Ht22 neuronal cell death after UVB irradiation by preventing superoxide formation. Int J Biol Sci. 2007 Feb 11; 3(4):198-204. PMID: 17389926.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    68. Xu XM, Carlson BA, Mix H, Zhang Y, Saira K, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL. Biosynthesis of selenocysteine on its tRNA in eukaryotes. PLoS Biol. 2007 Jan; 5(1):e4. PMID: 17194211.
      Citations: 112     Fields:    Translation:AnimalsCells
    69. Cassago A, Rodrigues EM, Prieto EL, Gaston KW, Alfonzo JD, Iribar MP, Berry MJ, Cruz AK, Thiemann OH. Identification of Leishmania selenoproteins and SECIS element. Mol Biochem Parasitol. 2006 Oct; 149(2):128-34. PMID: 16766053.
      Citations: 16     Fields:    Translation:AnimalsCells
    70. Stoytcheva Z, Tujebajeva RM, Harney JW, Berry MJ. Efficient incorporation of multiple selenocysteines involves an inefficient decoding step serving as a potential translational checkpoint and ribosome bottleneck. Mol Cell Biol. 2006 Dec; 26(24):9177-84. PMID: 17000762.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    71. Squires J, Berry MJ. Selenium, selenoproteins, and cancer. Hawaii Med J. 2006 Aug; 65(8):239-40. PMID: 17004624.
      Citations: 4     Fields:    Translation:HumansAnimals
    72. de Jesus LA, Hoffmann PR, Michaud T, Forry EP, Small-Howard A, Stillwell RJ, Morozova N, Harney JW, Berry MJ. Nuclear assembly of UGA decoding complexes on selenoprotein mRNAs: a mechanism for eluding nonsense-mediated decay? Mol Cell Biol. 2006 Mar; 26(5):1795-805. PMID: 16478999.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    73. Small-Howard A, Morozova N, Stoytcheva Z, Forry EP, Mansell JB, Harney JW, Carlson BA, Xu XM, Hatfield DL, Berry MJ. Supramolecular complexes mediate selenocysteine incorporation in vivo. Mol Cell Biol. 2006 Mar; 26(6):2337-46. PMID: 16508009.
      Citations: 55     Fields:    Translation:HumansCells
    74. Small-Howard AL, Berry MJ. Unique features of selenocysteine incorporation function within the context of general eukaryotic translational processes. Biochem Soc Trans. 2005 Dec; 33(Pt 6):1493-7. PMID: 16246153.
      Citations: 11     Fields:    Translation:AnimalsCells
    75. Berry MJ. Insights into the hierarchy of selenium incorporation. Nat Genet. 2005 Nov; 37(11):1162-3. PMID: 16254558.
      Citations: 12     Fields:    Translation:HumansCells
    76. Stillwell RJ, Berry MJ. Expanding the repertoire of the eukaryotic selenoproteome. Proc Natl Acad Sci U S A. 2005 Nov 08; 102(45):16123-4. PMID: 16263922.
      Citations: 2     Fields:    Translation:Animals
    77. Xu XM, Mix H, Carlson BA, Grabowski PJ, Gladyshev VN, Berry MJ, Hatfield DL. Evidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machinery. J Biol Chem. 2005 Dec 16; 280(50):41568-75. PMID: 16230358.
      Citations: 26     Fields:    Translation:AnimalsCells
    78. Shomaker TS, Easa D, Harrigan R, Berry M, Gubler D, Andrade N, Mau M, Palafox N, Blanchette PL, Rayner M, Kasuya R, Withy K, Davis J. Excellence in research and education at the John A. Burns School of Medicine: a tribute to Edwin Cadman's vision. Hawaii Med J. 2005 Oct; 64(10):263-9. PMID: 16294700.
      Citations:    Fields:    Translation:Humans
    79. Hoffmann PR, Berry MJ. Selenoprotein synthesis: a unique translational mechanism used by a diverse family of proteins. Thyroid. 2005 Aug; 15(8):769-75. PMID: 16131320.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    80. Berry MJ. Knowing when not to stop. Nat Struct Mol Biol. 2005 May; 12(5):389-90. PMID: 15870727.
      Citations: 8     Fields:    Translation:AnimalsCells
    81. Chen J, Small-Howard A, Yin A, Berry MJ. The responses of Ht22 cells to oxidative stress induced by buthionine sulfoximine (BSO). BMC Neurosci. 2005 Feb 12; 6:10. PMID: 15707499.
      Citations: 9     Fields:    Translation:AnimalsCells
    82. Carlson BA, Xu XM, Kryukov GV, Rao M, Berry MJ, Gladyshev VN, Hatfield DL. Identification and characterization of phosphoseryl-tRNA[Ser]Sec kinase. Proc Natl Acad Sci U S A. 2004 Aug 31; 101(35):12848-53. PMID: 15317934.
      Citations: 63     Fields:    Translation:Cells
    83. Morozova N, Forry EP, Shahid E, Zavacki AM, Harney JW, Kraytsberg Y, Berry MJ. Antioxidant function of a novel selenoprotein in Drosophila melanogaster. Genes Cells. 2003 Dec; 8(12):963-71. PMID: 14750951.
      Citations: 16     Fields:    Translation:AnimalsCells
    84. Chen J, Berry MJ. Selenium and selenoproteins in the brain and brain diseases. J Neurochem. 2003 Jul; 86(1):1-12. PMID: 12807419.
      Citations: 68     Fields:    Translation:HumansAnimals
    85. Zavacki AM, Mansell JB, Chung M, Klimovitsky B, Harney JW, Berry MJ. Coupled tRNA(Sec)-dependent assembly of the selenocysteine decoding apparatus. Mol Cell. 2003 Mar; 11(3):773-81. PMID: 12667458.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    86. Xu XM, Carlson BA, Grimm TA, Kutza J, Berry MJ, Arreola R, Fields KH, Shanmugam I, Jeang KT, Oroszlan S, Combs GF, Marx PA, Gladyshev VN, Clouse KA, Hatfield DL. Rhesus monkey simian immunodeficiency virus infection as a model for assessing the role of selenium in AIDS. . 2002 Dec 15; 31(5):453-63. PMID: 12473832.
      Citations:    
    87. Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002 Feb; 23(1):38-89. PMID: 11844744.
      Citations: 330     Fields:    Translation:HumansAnimalsCells
    88. Berry MJ, Martin GW, Tujebajeva R, Grundner-Culemann E, Mansell JB, Morozova N, Harney JW. Selenocysteine insertion sequence element characterization and selenoprotein expression. Methods Enzymol. 2002; 347:17-24. PMID: 11898404.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    89. Grundner-Culemann E, Martin GW, Tujebajeva R, Harney JW, Berry MJ. Interplay between termination and translation machinery in eukaryotic selenoprotein synthesis. J Mol Biol. 2001 Jul 20; 310(4):699-707. PMID: 11453681.
      Citations: 7     Fields:    Translation:HumansCells
    90. Martin GW, Berry MJ. Selenocysteine codons decrease polysome association on endogenous selenoprotein mRNAs. Genes Cells. 2001 Feb; 6(2):121-9. PMID: 11260257.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    91. Berry MJ, Tujebajeva RM, Copeland PR, Xu XM, Carlson BA, Martin GW, Low SC, Mansell JB, Grundner-Culemann E, Harney JW, Driscoll DM, Hatfield DL. Selenocysteine incorporation directed from the 3'UTR: characterization of eukaryotic EFsec and mechanistic implications. Biofactors. 2001; 14(1-4):17-24. PMID: 11568436.
      Citations: 20     Fields:    Translation:AnimalsCells
    92. Low SC, Grundner-Culemann E, Harney JW, Berry MJ. SECIS-SBP2 interactions dictate selenocysteine incorporation efficiency and selenoprotein hierarchy. EMBO J. 2000 Dec 15; 19(24):6882-90. PMID: 11118223.
      Citations: 56     Fields:    Translation:HumansCells
    93. Tujebajeva RM, Ransom DG, Harney JW, Berry MJ. Expression and characterization of nonmammalian selenoprotein P in the zebrafish, Danio rerio. Genes Cells. 2000 Nov; 5(11):897-903. PMID: 11122377.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    94. Tujebajeva RM, Copeland PR, Xu XM, Carlson BA, Harney JW, Driscoll DM, Hatfield DL, Berry MJ. Decoding apparatus for eukaryotic selenocysteine insertion. . 2000 Aug; 1(2):158-63. PMID: 11265756.
      Citations:    
    95. Tujebajeva RM, Harney JW, Berry MJ. Selenoprotein P expression, purification, and immunochemical characterization. J Biol Chem. 2000 Mar 03; 275(9):6288-94. PMID: 10692426.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    96. Buettner C, Harney JW, Berry MJ. The Caenorhabditis elegans homologue of thioredoxin reductase contains a selenocysteine insertion sequence (SECIS) element that differs from mammalian SECIS elements but directs selenocysteine incorporation. J Biol Chem. 1999 Jul 30; 274(31):21598-602. PMID: 10419466.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    97. Grundner-Culemann E, Martin GW, Harney JW, Berry MJ. Two distinct SECIS structures capable of directing selenocysteine incorporation in eukaryotes. RNA. 1999 May; 5(5):625-35. PMID: 10334333.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    98. Sun BC, Harney JW, Berry MJ, Larsen PR. The role of the active site cysteine in catalysis by type 1 iodothyronine deiodinase. Endocrinology. 1997 Dec; 138(12):5452-8. PMID: 9389531.
      Citations: 2     Fields:    Translation:AnimalsCells
    99. Berry MJ, Martin GW, Low SC. RNA and protein requirements for eukaryotic selenoprotein synthesis. Biomed Environ Sci. 1997 Sep; 10(2-3):182-9. PMID: 9315309.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    100. Toyoda N, Kaptein E, Berry MJ, Harney JW, Larsen PR, Visser TJ. Structure-activity relationships for thyroid hormone deiodination by mammalian type I iodothyronine deiodinases. Endocrinology. 1997 Jan; 138(1):213-9. PMID: 8977406.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    101. Low SC, Berry MJ. Knowing when not to stop: selenocysteine incorporation in eukaryotes. Trends Biochem Sci. 1996 Jun; 21(6):203-8. PMID: 8744353.
      Citations: 114     Fields:    Translation:Cells
    102. Low SC, Harney JW, Berry MJ. Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis. J Biol Chem. 1995 Sep 15; 270(37):21659-64. PMID: 7665581.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    103. Maia AL, Berry MJ, Sabbag R, Harney JW, Larsen PR. Structural and functional differences in the dio1 gene in mice with inherited type 1 deiodinase deficiency. Mol Endocrinol. 1995 Aug; 9(8):969-80. PMID: 7476994.
      Citations: 8     Fields:    Translation:AnimalsCells
    104. Toyoda N, Berry MJ, Harney JW, Larsen PR. Topological analysis of the integral membrane protein, type 1 iodothyronine deiodinase (D1). J Biol Chem. 1995 May 19; 270(20):12310-8. PMID: 7744884.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    105. Larsen PR, Berry MJ. Nutritional and hormonal regulation of thyroid hormone deiodinases. Annu Rev Nutr. 1995; 15:323-52. PMID: 8527223.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    106. Berry MJ, Harney JW, Ohama T, Hatfield DL. Selenocysteine insertion or termination: factors affecting UGA codon fate and complementary anticodon:codon mutations. Nucleic Acids Res. 1994 Sep 11; 22(18):3753-9. PMID: 7937088.
      Citations: 36     Fields:    Translation:Cells
    107. Toyoda N, Harney JW, Berry MJ, Larsen PR. Identification of critical amino acids for 3,5,3'-triiodothyronine deiodination by human type 1 deiodinase based on comparative functional-structural analyses of the human, dog, and rat enzymes. J Biol Chem. 1994 Aug 12; 269(32):20329-34. PMID: 8051127.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    108. Larsen PR, Berry MJ. Type I iodothyronine deiodinase: unexpected complexities in a simple deiodination reaction. Thyroid. 1994; 4(3):357-62. PMID: 7833676.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    109. Berry MJ, Larsen PR. Recognition of UGA as a selenocysteine codon in eukaryotes: a review of recent progress. Biochem Soc Trans. 1993 Nov; 21(4):827-32. PMID: 8132075.
      Citations: 7     Fields:    Translation:AnimalsCells
    110. Berry MJ, Grieco D, Taylor BA, Maia AL, Kieffer JD, Beamer W, Glover E, Poland A, Larsen PR. Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency. J Clin Invest. 1993 Sep; 92(3):1517-28. PMID: 8104199.
      Citations: 21     Fields:    Translation:AnimalsCells
    111. Berry MJ, Banu L, Harney JW, Larsen PR. Functional characterization of the eukaryotic SECIS elements which direct selenocysteine insertion at UGA codons. EMBO J. 1993 Aug; 12(8):3315-22. PMID: 8344267.
      Citations: 102     Fields:    Translation:AnimalsCells
    112. Lee WS, Berry MJ, Hediger MA, Larsen PR. The type I iodothyronine 5'-deiodinase messenger ribonucleic acid is localized to the S3 segment of the rat kidney proximal tubule. Endocrinology. 1993 May; 132(5):2136-40. PMID: 8477661.
      Citations: 6     Fields:    Translation:Animals
    113. Berry MJ, Larsen PR. Molecular cloning of the selenocysteine-containing enzyme type I iodothyronine deiodinase. Am J Clin Nutr. 1993 02; 57(2 Suppl):249S-255S. PMID: 8427198.
      Citations: 1     Fields:    Translation:HumansAnimals
    114. Mandel SJ, Berry MJ, Kieffer JD, Harney JW, Warne RL, Larsen PR. Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase. J Clin Endocrinol Metab. 1992 Oct; 75(4):1133-9. PMID: 1400883.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    115. Berry MJ, Maia AL, Kieffer JD, Harney JW, Larsen PR. Substitution of cysteine for selenocysteine in type I iodothyronine deiodinase reduces the catalytic efficiency of the protein but enhances its translation. Endocrinology. 1992 Oct; 131(4):1848-52. PMID: 1396330.
      Citations: 35     Fields:    Translation:Cells
    116. Berry MJ. Identification of essential histidine residues in rat type I iodothyronine deiodinase. J Biol Chem. 1992 Sep 05; 267(25):18055-9. PMID: 1517238.
      Citations: 5     Fields:    Translation:AnimalsCells
    117. Berry MJ, Larsen PR. The role of selenium in thyroid hormone action. Endocr Rev. 1992 May; 13(2):207-19. PMID: 1535587.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    118. Berry MJ, Banu L, Chen YY, Mandel SJ, Kieffer JD, Harney JW, Larsen PR. Recognition of UGA as a selenocysteine codon in type I deiodinase requires sequences in the 3' untranslated region. Nature. 1991 Sep 19; 353(6341):273-6. PMID: 1832744.
      Citations: 162     Fields:    Translation:HumansAnimalsCells
    119. Berry MJ, Kieffer JD, Harney JW, Larsen PR. Selenocysteine confers the biochemical properties characteristic of the type I iodothyronine deiodinase. J Biol Chem. 1991 Aug 05; 266(22):14155-8. PMID: 1830583.
      Citations: 30     Fields:    Translation:Animals
    120. Berry MJ, Kieffer JD, Larsen PR. Evidence that cysteine, not selenocysteine, is in the catalytic site of type II iodothyronine deiodinase. Endocrinology. 1991 Jul; 129(1):550-2. PMID: 1829034.
      Citations: 11     Fields:    Translation:AnimalsCells
    121. Berry MJ, Banu L, Larsen PR. Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature. 1991 Jan 31; 349(6308):438-40. PMID: 1825132.
      Citations: 108     Fields:    Translation:AnimalsCells
    122. Berry MJ, Kates AL, Larsen PR. Thyroid hormone regulates type I deiodinase messenger RNA in rat liver. Mol Endocrinol. 1990 May; 4(5):743-8. PMID: 2274056.
      Citations: 16     Fields:    Translation:AnimalsCells
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