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Rosa A. Maldonado

Faculty RankAssociate Professor
InstitutionUniversity of Texas at El Paso
DepartmentBiological Sciences
AddressUniversity of Texas at El Paso
500 West University Avenue
El Paso TX 79902
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    Collapse Biography 
    Collapse awards and honors
    1992 - 1996Ph.D. fellowship , Consejo Venezolano de Investigaciones Cientificas y Tecnologicas (CONICIT), Venezuela.
    1997 - 1999Wellcome Trust International Fellow, Wellcome Trust, UK
    1998 - 2005Member, Brazilian Society of Protozoology (SBPz)
    1999 - 2003Post Doctoral Fellowship, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Sao Paulo, Brazil
    2004 - 2017Member, Member of American Society of Microbiology (ASM
    2004 - 2004Visiting Professor, Federal University of Sao Paulo (UNIFESP), Sao Paulo, SP, Brazil,
    2005 - 2017 Member, American Society of Parasitology.
    2005 - 2012Member, SIGMA Xi, The Scientific Research Society.
    2005 - 2017Member, Society for Advancement of Chicanos and Natives Americans in Sciences (SACNAS)
    2007Honorary Member , Golden Key International Honour Society, UTEP chapter
    2008 - 2017Faculty Advisor of the Student Chapter, American Society for Microbiology
    2011 - 2013President, American Society for Microbiology Rio Grande Branch.
    2011 - 2017Program Director, Bridges to Baccalaureate-NIH.
    2012 - 2014Vice-President, Bridges PD&CO.
    2013 - 2014Faculty Advisor of the Year American Society of Microbiology Student Chapter, University of Texas at El Paso
    2014 - 2017Director, Border Biomedical Research Center Student Development Program
    2014 - 2015Interim President, Bridges PD&CO.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Alonso-Vega C, Urbina JA, Sanz S, Pinazo MJ, Pinto JJ, Gonzalez VR, Rojas G, Ortiz L, Garcia W, Lozano D, Soy D, Maldonado RA, Nagarkatti R, Debrabant A, Schijman A, Thomas MC, L?pez MC, Michael K, Ribeiro I, Gascon J, Torrico F, Almeida IC. New chemotherapy regimens and biomarkers for Chagas disease: the rationale and design of the TESEO study, an open-label, randomised, prospective, phase-2 clinical trial in the Plurinational State of Bolivia. BMJ Open. 2021 12 31; 11(12):e052897. PMID: 34972765.
      Citations: 9     Fields:    Translation:HumansAnimalsCTClinical Trials
    2. Rodriguez F, Luna BS, Calderon O, Manriquez-Roman C, Amezcua-Winter K, Cedillo J, Garcia-Vazquez R, Tejeda IA, Romero A, Waldrup K, Watts DM, Khatchikian C, Maldonado RA. Surveillance of Trypanosoma cruzi infection in Triatomine vectors, feral dogs and cats, and wild animals in and around El Paso county, Texas, and New Mexico. PLoS Negl Trop Dis. 2021 02; 15(2):e0009147. PMID: 33600455.
      Citations: 10     Fields:    Translation:HumansAnimalsPHPublic Health
    3. Rodriguez F, John SF, Iniguez E, Montalvo S, Michael K, White L, Liang D, Olaleye OA, Maldonado RA. In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors. Antimicrob Agents Chemother. 2020 05 21; 64(6). PMID: 32179532.
      Citations: 5     Fields:    Translation:Animals
    4. Portillo S, Zepeda BG, Iniguez E, Olivas JJ, Karimi NH, Moreira OC, Marques AF, Michael K, Maldonado RA, Almeida IC. A prophylactic a-Gal-based glycovaccine effectively protects against murine acute Chagas disease. NPJ Vaccines. 2019; 4:13. PMID: 30911415.
    5. Ortega-Rodriguez U, Portillo S, Ashmus RA, Duran JA, Schocker NS, Iniguez E, Montoya AL, Zepeda BG, Olivas JJ, Karimi NH, Alonso-Padilla J, Izquierdo L, Pinazo MJ, de Noya BA, Noya O, Maldonado RA, Torrico F, Gascon J, Michael K, Almeida IC. Purification of Glycosylphosphatidylinositol-Anchored Mucins from Trypanosoma cruzi Trypomastigotes and Synthesis of a-Gal-Containing Neoglycoproteins: Application as Biomarkers for Reliable Diagnosis and Early Assessment of Chemotherapeutic Outcomes of Chagas Disease. Methods Mol Biol. 2019; 1955:287-308. PMID: 30868536.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    6. Rodriguez F, Iniguez E, Pena Contreras G, Ahmed H, Costa TEMM, Skouta R, Maldonado RA. Development of Thiophene Compounds as Potent Chemotherapies for the Treatment of Cutaneous Leishmaniasis Caused by Leishmania major. Molecules. 2018 07 04; 23(7). PMID: 29973498.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. Iniguez E, Schocker NS, Subramaniam K, Portillo S, Montoya AL, Al-Salem WS, Torres CL, Rodriguez F, Moreira OC, Acosta-Serrano A, Michael K, Almeida IC, Maldonado RA. An a-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major. PLoS Negl Trop Dis. 2017 Oct; 11(10):e0006039. PMID: 29069089.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    8. Bartolome F, Antequera D, Tavares E, Pascual C, Maldonado R, Camins A, Carro E. Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin. J Neuroinflammation. 2017 01 31; 14(1):26. PMID: 28143489.
      Citations: 15     Fields:    Translation:AnimalsCells
    9. Iniguez E, Varela-Ramirez A, Mart?nez A, Torres CL, S?nchez-Delgado RA, Maldonado RA. Ruthenium-Clotrimazole complex has significant efficacy in the murine model of cutaneous leishmaniasis. Acta Trop. 2016 Dec; 164:402-410. PMID: 27693373.
      Citations: 3     Fields:    Translation:Animals
    10. Herrera LJ, Brand S, Santos A, Nohara LL, Harrison J, Norcross NR, Thompson S, Smith V, Lema C, Varela-Ramirez A, Gilbert IH, Almeida IC, Maldonado RA. Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004540. PMID: 27128971.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    11. Iniguez EA, Perez A, Maldonado RA, Skouta R. Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania major. Bioorg Med Chem Lett. 2015 Nov 15; 25(22):5315-20. PMID: 26410073.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    12. Buhaya MH, Galvan S, Maldonado RA. Incidence of Trypanosoma cruzi infection in triatomines collected at Indio Mountains Research Station. Acta Trop. 2015 Oct; 150:97-9. PMID: 26193424.
      Citations: 8     Fields:    Translation:HumansAnimalsPHPublic Health
    13. Vasquez MA, Iniguez E, Das U, Beverley SM, Herrera LJ, Dimmock JR, Maldonado RA. Evaluation of a,?-unsaturated ketones as antileishmanial agents. Antimicrob Agents Chemother. 2015; 59(6):3598-601. PMID: 25801571.
      Citations: 1     Fields:    Translation:AnimalsCells
    14. Gonzalez H, Lema C, Kirken RA, Maldonado RA, Varela-Ramirez A, Aguilera RJ. Arsenic-exposed Keratinocytes Exhibit Differential microRNAs Expression Profile; Potential Implication of miR-21, miR-200a and miR-141 in Melanoma Pathway. Clin Cancer Drugs. 2015; 2(2):138-147. PMID: 27054085.
    15. Serna C, Lara JA, Rodrigues SP, Marques AF, Almeida IC, Maldonado RA. A synthetic peptide from Trypanosoma cruzi mucin-like associated surface protein as candidate for a vaccine against Chagas disease. Vaccine. 2014 Jun 12; 32(28):3525-32. PMID: 24793944.
      Citations: 25     Fields:    Translation:AnimalsCells
    16. Iniguez E, S?nchez A, Vasquez MA, Mart?nez A, Olivas J, Sattler A, S?nchez-Delgado RA, Maldonado RA. Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cells. J Biol Inorg Chem. 2013 Oct; 18(7):779-90. PMID: 23881220.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    17. Mendez TL, De Chatterjee A, Duarte TT, Gazos-Lopes F, Robles-Martinez L, Roy D, Sun J, Maldonado RA, Roychowdhury S, Almeida IC, Das S. Glucosylceramide transferase activity is critical for encystation and viable cyst production by an intestinal protozoan, Giardia lamblia. J Biol Chem. 2013 Jun 07; 288(23):16747-16760. PMID: 23589290.
      Citations: 5     Fields:    Translation:HumansAnimals
    18. Mart?nez A, Carreon T, Iniguez E, Anzellotti A, S?nchez A, Tyan M, Sattler A, Herrera L, Maldonado RA, S?nchez-Delgado RA. Searching for new chemotherapies for tropical diseases: ruthenium-clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low toxicity toward normal mammalian cells. J Med Chem. 2012 Apr 26; 55(8):3867-77. PMID: 22448965.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    19. Lara D, Feng Y, Bader J, Savage PB, Maldonado RA. Anti-trypanosomatid activity of ceragenins. J Parasitol. 2010 Jun; 96(3):638-42. PMID: 19958044.
      Citations: 14     Fields:    Translation:AnimalsCells
    20. Ramos EI, Garza KM, Krauth-Siegel RL, Bader J, Martinez LE, Maldonado RA. 2,3-diphenyl-1,4-naphthoquinone: a potential chemotherapeutic agent against Trypanosoma cruzi. J Parasitol. 2009 Apr; 95(2):461-6. PMID: 18788881.
      Citations: 9     Fields:    Translation:AnimalsCells
    21. Esteves E, Foga?a AC, Maldonado R, Silva FD, Manso PP, Pelajo-Machado M, Valle D, Daffre S. Antimicrobial activity in the tick Rhipicephalus (Boophilus) microplus eggs: Cellular localization and temporal expression of microplusin during oogenesis and embryogenesis. Dev Comp Immunol. 2009 Aug; 33(8):913-9. PMID: 19454333.
      Citations: 22     Fields:    Translation:AnimalsCells
    22. Hernandez Y, Shpak M, Duarte TT, Mendez TL, Maldonado RA, Roychowdhury S, Rodrigues ML, Das S. Novel role of sphingolipid synthesis genes in regulating giardial encystation. Infect Immun. 2008 Jul; 76(7):2939-49. PMID: 18426892.
      Citations: 11     Fields:    Translation:AnimalsCells
    23. Barbosa FM, Daffre S, Maldonado RA, Miranda A, Nimrichter L, Rodrigues ML. Gomesin, a peptide produced by the spider Acanthoscurria gomesiana, is a potent anticryptococcal agent that acts in synergism with fluconazole. FEMS Microbiol Lett. 2007 Sep; 274(2):279-86. PMID: 17645524.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    24. Maldonado RA, Kuniyoshi RK, Linss JG, Almeida IC. Trypanosoma cruzi oleate desaturase: molecular characterization and comparative analysis in other trypanosomatids. J Parasitol. 2006 Oct; 92(5):1064-74. PMID: 17152952.
      Citations: 13     Fields:    Translation:AnimalsCells
    25. Nascimento EM, Gehrke Fde S, Maldonado RA, Colombo S, Silva LJ, Schumaker TT. Detection of Brazilian spotted fever infection by polymerase chain reaction in a patient from the state of S?o Paulo. Mem Inst Oswaldo Cruz. 2005 May; 100(3):277-9. PMID: 16113868.
      Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    26. Mi?ano FJ, Tavares E, Maldonado R. Role of endogenous macrophage inflammatory protein-2 in regulating fever induced by bacterial endotoxin in normal and immunosuppressed rats. Clin Exp Pharmacol Physiol. 2004 Oct; 31(10):723-31. PMID: 15554915.
      Citations: 3     Fields:    Translation:AnimalsPHPublic Health
    27. Maldonado RA, Fairlamb AH. Cloning of a pyruvate phosphate dikinase from Trypanosoma cruzi. Mol Biochem Parasitol. 2001 Feb; 112(2):183-91. PMID: 11223125.
      Citations: 3     Fields:    Translation:AnimalsCells
    28. Maldonado RA, Mirzoeva S, Godsel LM, Lukas TJ, Goldenberg S, Watterson DM, Engman DM. Identification of calcium binding sites in the trypanosome flagellar calcium-acyl switch protein. Mol Biochem Parasitol. 1999 Jun 25; 101(1-2):61-70. PMID: 10413043.
      Citations: 11     Fields:    Translation:AnimalsCells
    29. Maldonado RA, Linss J, Thomaz N, Olson CL, Engman DM, Goldenberg S. Homologues of the 24-kDa flagellar Ca(2+)-binding protein gene of Trypanosoma cruzi are present in other members of the Trypanosomatidae family. Exp Parasitol. 1997 Jul; 86(3):200-5. PMID: 9225770.
      Citations: 11     Fields:    Translation:AnimalsCells
    30. Maldonado RA, Molina J, Payares G, Urbina JA. Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas' disease. Antimicrob Agents Chemother. 1993 Jun; 37(6):1353-9. PMID: 8328786.
      Citations: 18     Fields:    Translation:Animals
    31. Urbina JA, Lazardi K, Marchan E, Visbal G, Aguirre T, Piras MM, Piras R, Maldonado RA, Payares G, de Souza W. Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies. Antimicrob Agents Chemother. 1993 Mar; 37(3):580-91. PMID: 8460926.
      Citations: 35     Fields:    Translation:AnimalsCells
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