Xue Zhu

Title	Dr.
Faculty Rank	Instructor
Institution	Florida A&M University
Department	College of Pharmacy and Pharmaceutical Sciences, Institute of Public Health
Address	Florida A&M University Tallahassee FL 32307
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Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Bulusu R, Okoro J, Frimpong E, Krishnan S, Yoon S, Han B, Zhu X, Agyare E. Enhanced anticancer activity of novel pyrimidine nucleoside analog in pancreatic cancer. Am J Cancer Res. 2025; 15(8):3740-3761. PMID: 40948519.

Citations:
Okoro J, Bulusu R, Frimpong E, Zhu X, Rogers S, Agyare E. A novel gemcitabine analog as a potential anticancer agent: synthesis and in-vitro evaluation against pancreatic cancer. Am J Cancer Res. 2025; 15(2):684-704. PMID: 40084373.

Citations:
Frimpong E, Bulusu R, Okoro J, Inkoom A, Ndemazie N, Rogers S, Zhu X, Han B, Agyare E. Development of novel pyrimidine nucleoside analogs as potential anticancer agents: Synthesis, characterization, and In-vitro evaluation against pancreatic cancer. Eur J Pharm Sci. 2024 May 01; 196:106754. PMID: 38554983.

Citations: 2 Fields:
Che Chemistry Pha Pharmacology
Translation:Humans Cells
Inkoom A, Ndemazie NB, Smith T, Frimpong E, Bulusu R, Poku R, Zhu X, Han B, Trevino J, Agyare E. Biological evaluation of novel gemcitabine analog in patient-derived xenograft models of pancreatic cancer. BMC Cancer. 2023 May 13; 23(1):435. PMID: 37179357.

Citations: 6 Fields:
Neo Neoplasms
Translation:Humans Animals Cells
Ndemazie NB, Bulusu R, Zhu XY, Frimpong EK, Inkoom A, Okoro J, Ebesoh D, Rogers S, Han B, Agyare E. Evaluation of Anticancer Activity of Zhubech, a New 5-FU Analog Liposomal Formulation, against Pancreatic Cancer. Int J Mol Sci. 2023 Feb 21; 24(5). PMID: 36901721.

Citations: 5 Fields:
Bio Biochemistry Che Chemistry Mol Molecular Biology
Translation:Animals
Ndemazie NB, Inkoom A, Ebesoh D, Bulusu R, Frimpong E, Trevino J, Han B, Zhu X, Agyare E. Synthesis, characterization, and anticancer evaluation of 1,3-bistetrahydrofuran-2yl-5-FU as a potential agent for pancreatic cancer. BMC Cancer. 2022 Dec 22; 22(1):1345. PMID: 36550419.

Citations: 3 Fields:
Neo Neoplasms
Translation:Animals Cells
Asong G, Zhu XY, Bricker B, Andey T, Amissah F, Lamango N, Ablordeppey SY. New analogs of SYA013 as sigma-2 ligands with anticancer activity. Bioorg Med Chem. 2019 06 15; 27(12):2629-2636. PMID: 30987780.

Citations: 6 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Cells
Al-Ghanim L, Zhu XY, Asong G, Ablordeppey SY. SYA 013 analogs as moderately selective sigma-2 (s2) ligands: Structure-affinity relationship studies. Bioorg Med Chem. 2019 06 15; 27(12):2421-2426. PMID: 30737135.

Citations: 3 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Animals Cells
Ofori E, Zhu XY, Etukala JR, Bricker BA, Ablordeppey SY. Synthesis and evaluation of the structural elements in alkylated tetrahydroisoquinolines for binding to CNS receptors. Bioorg Med Chem. 2016 11 15; 24(22):5730-5740. PMID: 27717652.

Citations: 5 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Cells
Etukala JR, Zhu XY, Eyunni SV, Onyameh EK, Ofori E, Bricker BA, Kang HJ, Huang XP, Roth BL, Ablordeppey SY. Development of CNS multi-receptor ligands: Modification of known D2 pharmacophores. Bioorg Med Chem. 2016 08 15; 24(16):3671-9. PMID: 27364609.

Citations: 1 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Animals
Ofori E, Zhu XY, Etukala JR, Peprah K, Jordan KR, Adkins AA, Bricker BA, Kang HJ, Huang XP, Roth BL, Ablordeppey SY. Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands. Bioorg Med Chem. 2016 08 15; 24(16):3464-71. PMID: 27312422.

Citations: 7 Fields:
Bio Biochemistry Che Chemistry
Sampson D, Bricker B, Zhu XY, Peprah K, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Further evaluation of the tropane analogs of haloperidol. Bioorg Med Chem Lett. 2014 Sep 01; 24(17):4294-7. PMID: 25070422.

Citations: 5 Fields:
Bio Biochemistry Che Chemistry
Translation:Animals Cells
Sampson D, Zhu XY, Eyunni SV, Etukala JR, Ofori E, Bricker B, Lamango NS, Setola V, Roth BL, Ablordeppey SY. Identification of a new selective dopamine D4 receptor ligand. Bioorg Med Chem. 2014 Jun 15; 22(12):3105-14. PMID: 24800940.

Citations: 15 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Animals Cells
Bolden S, Zhu XY, Etukala JR, Boateng C, Mazu T, Flores-Rozas H, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Structure-activity relationship (SAR) and preliminary mode of action studies of 3-substituted benzylthioquinolinium iodide as anti-opportunistic infection agents. Eur J Med Chem. 2013; 70:130-42. PMID: 24141203.

Citations: 4 Fields:
Che Chemistry
Translation:Animals Cells
Bolden S, Boateng CA, Zhu XY, Etukala JR, Eyunni SK, Jacob MR, Khan SI, Ablordeppey SY. CoMFA studies and in vitro evaluation of some 3-substituted benzylthio quinolinium salts as anticryptococcal agents. Bioorg Med Chem. 2013 Nov 15; 21(22):7194-201. PMID: 24080102.

Citations: 4 Fields:
Bio Biochemistry Che Chemistry
Translation:Animals Cells
Zhu XY, Etukala JR, Eyunni SV, Setola V, Roth BL, Ablordeppey SY. Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): a search for new dual-acting agents as potential antidepressants. Eur J Med Chem. 2012 Jul; 53:124-32. PMID: 22520153.

Citations: 7 Fields:
Che Chemistry
Peprah K, Zhu XY, Eyunni SV, Etukala JR, Setola V, Roth BL, Ablordeppey SY. Structure-activity relationship studies of SYA 013, a homopiperazine analog of haloperidol. Bioorg Med Chem. 2012 Mar 01; 20(5):1671-8. PMID: 22336245.

Citations: 15 Fields:
Bio Biochemistry Che Chemistry
Peprah K, Zhu XY, Eyunni SV, Setola V, Roth BL, Ablordeppey SY. Multi-receptor drug design: Haloperidol as a scaffold for the design and synthesis of atypical antipsychotic agents. Bioorg Med Chem. 2012 Feb 01; 20(3):1291-7. PMID: 22245230.

Citations: 22 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans
Boateng CA, Zhu XY, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Optimization of 3-(phenylthio)quinolinium compounds against opportunistic fungal pathogens. Eur J Med Chem. 2011 May; 46(5):1789-97. PMID: 21402432.

Citations: 5 Fields:
Che Chemistry
Translation:Animals Cells
Mazu TK, Etukala JR, Zhu XY, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Identification of 3-phenylaminoquinolinium and 3-phenylaminopyridinium salts as new agents against opportunistic fungal pathogens. Bioorg Med Chem. 2011 Jan 01; 19(1):524-33. PMID: 21130660.

Citations: 4 Fields:
Bio Biochemistry Che Chemistry
Translation:Animals Cells
Sikazwe DM, Nkansah NT, Altundas R, Zhu XY, Roth BL, Setola V, Ablordeppey SY. Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups. Bioorg Med Chem. 2009 Feb 15; 17(4):1716-23. PMID: 19155177.

Citations: 6 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Cells
Ablordeppey SY, Altundas R, Bricker B, Zhu XY, Kumar EV, Jackson T, Khan A, Roth BL. Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one. Bioorg Med Chem. 2008 Aug 01; 16(15):7291-301. PMID: 18595716.

Citations: 18 Fields:
Bio Biochemistry Che Chemistry
Translation:Animals Cells
Zhu XY, Mardenborough LG, Li S, Khan A, Zhang W, Fan P, Jacob M, Khan S, Walker L, Ablordeppey SY. Synthesis and evaluation of isosteres of N-methyl indolo[3,2-b]-quinoline (cryptolepine) as new antiinfective agents. Bioorg Med Chem. 2007 Jan 15; 15(2):686-95. PMID: 17134906.

Citations: 12 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Animals Cells
Mardenborough LG, Zhu XY, Fan P, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Identification of bis-quindolines as new antiinfective agents. Bioorg Med Chem. 2005 Jun 02; 13(12):3955-63. PMID: 15911310.

Citations: 9 Fields:
Bio Biochemistry Che Chemistry
Translation:Animals Cells

Year	Publications
2005	1
2006	1
2008	2
2010	1
2011	2
2012	2
2013	2
2014	2
2016	3
2019	2
2022	1
2023	2
2024	1
2025	2

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