"alpha-Globins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Members of the alpha-globin family. In humans, they are encoded in a gene cluster on CHROMOSOME 16. They include zeta-globin and alpha-globin. There are also pseudogenes of zeta (theta-zeta) and alpha (theta-alpha) in the cluster. Adult HEMOGLOBIN is comprised of 2 alpha-globin chains and 2 beta-globin chains.
Descriptor ID |
D055542
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MeSH Number(s) |
D12.776.124.400.434.320 D12.776.422.316.762.403.320
|
Concept/Terms |
alpha-1 Globin- alpha-1 Globin
- Globin, alpha-1
- alpha 1 Globin
- alpha 1-globin
- 1-globin, alpha
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Below are MeSH descriptors whose meaning is more general than "alpha-Globins".
Below are MeSH descriptors whose meaning is more specific than "alpha-Globins".
This graph shows the total number of publications written about "alpha-Globins" by people in this website by year, and whether "alpha-Globins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 1 | 2 |
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Below are the most recent publications written about "alpha-Globins" by people in Profiles.
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Raffield LM, Ulirsch JC, Naik RP, Lessard S, Handsaker RE, Jain D, Kang HM, Pankratz N, Auer PL, Bao EL, Smith JD, Lange LA, Lange EM, Li Y, Thornton TA, Young BA, Abecasis GR, Laurie CC, Nickerson DA, McCarroll SA, Correa A, Wilson JG, Lettre G, Sankaran VG, Reiner AP. Common a-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease. PLoS Genet. 2018 03; 14(3):e1007293.
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Myers JN, Sch?ffer MW, Korolkova OY, Williams AD, Gangula PR, M'Koma AE. Implications of the colonic deposition of free hemoglobin-a chain: a previously unknown tissue by-product in inflammatory bowel disease. Inflamm Bowel Dis. 2014 09; 20(9):1530-47.
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Darbari DS, Nouraie M, Taylor JG, Brugnara C, Castro O, Ballas SK. Alpha-thalassaemia and response to hydroxyurea in sickle cell anaemia. Eur J Haematol. 2014 Apr; 92(4):341-5.