Lymphotoxin beta Receptor
"Lymphotoxin beta Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the tumor necrosis factor receptor superfamily. It has specificity for LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER and TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14. The receptor plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER T-CELLS. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Descriptor ID |
D053259
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MeSH Number(s) |
D12.776.543.750.705.852.760.245
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Concept/Terms |
Lymphotoxin beta Receptor- Lymphotoxin beta Receptor
- Receptor, Lymphotoxin beta
- beta Receptor, Lymphotoxin
- TNFR Superfamily, Member 3
- Tumor Necrosis Factor Receptor Superfamily, Member 3
- Receptors, Lymphotoxin beta
- Lymphotoxin beta Receptors
- beta Receptors, Lymphotoxin
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Below are MeSH descriptors whose meaning is more general than "Lymphotoxin beta Receptor".
Below are MeSH descriptors whose meaning is more specific than "Lymphotoxin beta Receptor".
This graph shows the total number of publications written about "Lymphotoxin beta Receptor" by people in this website by year, and whether "Lymphotoxin beta Receptor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lymphotoxin beta Receptor" by people in Profiles.
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Parnell EA, Walch EM, Lo DD. Inducible Colonic M Cells Are Dependent on TNFR2 but Not Lt?r, Identifying Distinct Signalling Requirements for Constitutive Versus Inducible M Cells. J Crohns Colitis. 2017 Jun 01; 11(6):751-760.
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Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y. Lymphotoxin ? receptor signaling induces IL-8 production in human bronchial epithelial cells. PLoS One. 2014; 9(12):e114791.
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Wang J, Lopez-Fraga M, Rynko A, Lo DD. TNFR and LTbetaR agonists induce follicle-associated epithelium and M cell specific genes in rat and human intestinal epithelial cells. Cytokine. 2009 Jul; 47(1):69-76.
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Plant SR, Iocca HA, Wang Y, Thrash JC, O'Connor BP, Arnett HA, Fu YX, Carson MJ, Ting JP. Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. J Neurosci. 2007 Jul 11; 27(28):7429-37.
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Elewaut D, Shaikh RB, Hammond KJ, De Winter H, Leishman AJ, Sidobre S, Turovskaya O, Prigozy TI, Ma L, Banks TA, Lo D, Ware CF, Cheroutre H, Kronenberg M. NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells. J Exp Med. 2003 Jun 16; 197(12):1623-33.