Small-Conductance Calcium-Activated Potassium Channels
"Small-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium-activated potassium channels that are found primarily in excitable CELLS. They play important roles in the transmission of ACTION POTENTIALS and generate a long-lasting hyperpolarization known as the slow afterhyperpolarization.
| Descriptor ID |
D051640
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| MeSH Number(s) |
D12.776.157.530.400.600.150.750 D12.776.543.550.450.750.150.750 D12.776.543.585.400.750.150.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Small-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Small-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Small-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Small-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Murthy SR, Sherrin T, Jansen C, Nijholt I, Robles M, Dolga AM, Andreotti N, Sabatier JM, Knaus HG, Penner R, Todorovic C, Blank T. Small-conductance Ca2+-activated potassium type 2 channels regulate the formation of contextual fear memory. PLoS One. 2015; 10(5):e0127264.
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Andres MA. Glucose-sensitivity of the afterhyperpolarization potential: role of SK1 channel in insulin-secreting cells. Gen Comp Endocrinol. 2012 Sep 15; 178(3):459-62.
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Deister CA, Chan CS, Surmeier DJ, Wilson CJ. Calcium-activated SK channels influence voltage-gated ion channels to determine the precision of firing in globus pallidus neurons. J Neurosci. 2009 Jul 01; 29(26):8452-61.
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Mulholland PJ, Hopf FW, Bukiya AN, Martin GE, Liu J, Dopico AM, Bonci A, Treistman SN, Chandler LJ. Sizing up ethanol-induced plasticity: the role of small and large conductance calcium-activated potassium channels. Alcohol Clin Exp Res. 2009 Jul; 33(7):1125-35.
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Andres MA, Baptista NC, Efird JT, Ogata KK, Bellinger FP, Zeyda T. Depletion of SK1 channel subunits leads to constitutive insulin secretion. FEBS Lett. 2009 Jan 22; 583(2):369-76.
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Ramanathan S, Tkatch T, Atherton JF, Wilson CJ, Bevan MD. D2-like dopamine receptors modulate SKCa channel function in subthalamic nucleus neurons through inhibition of Cav2.2 channels. J Neurophysiol. 2008 Feb; 99(2):442-59.
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Teagarden M, Atherton JF, Bevan MD, Wilson CJ. Accumulation of cytoplasmic calcium, but not apamin-sensitive afterhyperpolarization current, during high frequency firing in rat subthalamic nucleus cells. J Physiol. 2008 Feb 01; 586(3):817-33.
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Hallworth NE, Wilson CJ, Bevan MD. Apamin-sensitive small conductance calcium-activated potassium channels, through their selective coupling to voltage-gated calcium channels, are critical determinants of the precision, pace, and pattern of action potential generation in rat subthalamic nucleus neurons in vitro. J Neurosci. 2003 Aug 20; 23(20):7525-42.