Serine C-Palmitoyltransferase
"Serine C-Palmitoyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.
Descriptor ID |
D051102
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MeSH Number(s) |
D08.811.913.050.668
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Concept/Terms |
Serine C-Palmitoyltransferase- Serine C-Palmitoyltransferase
- C-Palmitoyltransferase, Serine
- Serine C Palmitoyltransferase
- Serine Palmitoyltransferase
- Palmitoyltransferase, Serine
- Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating)
- Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating)
Long Chain Base Biosynthesis Protein 2- Long Chain Base Biosynthesis Protein 2
- Serine-Palmitoyl-CoA Transferase 2
- Serine Palmitoyl CoA Transferase 2
- Transferase 2, Serine-Palmitoyl-CoA
- Serine Palmitoyltransferase 2
- Palmitoyltransferase 2, Serine
- Serine Palmitoyltransferase, Long Chain Base Subunit 2
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Below are MeSH descriptors whose meaning is more general than "Serine C-Palmitoyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Serine C-Palmitoyltransferase".
This graph shows the total number of publications written about "Serine C-Palmitoyltransferase" by people in this website by year, and whether "Serine C-Palmitoyltransferase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serine C-Palmitoyltransferase" by people in Profiles.
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Liu Q, Zhang L, Allman EL, Hubbard TD, Murray IA, Hao F, Tian Y, Gui W, Nichols RG, Smith PB, Anitha M, Perdew GH, Patterson AD. The aryl hydrocarbon receptor activates ceramide biosynthesis in mice contributing to hepatic lipogenesis. Toxicology. 2021 06 30; 458:152831.
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Myers SJ, Malladi CS, Hyland RA, Bautista T, Boadle R, Robinson PJ, Nicholson GA. Mutations in the SPTLC1 protein cause mitochondrial structural abnormalities and endoplasmic reticulum stress in lymphoblasts. DNA Cell Biol. 2014 Jul; 33(7):399-407.
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Fridberg A, Olson CL, Nakayasu ES, Tyler KM, Almeida IC, Engman DM. Sphingolipid synthesis is necessary for kinetoplast segregation and cytokinesis in Trypanosoma brucei. J Cell Sci. 2008 Feb 15; 121(Pt 4):522-35.