"Synaptotagmin I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
| Descriptor ID |
D050863
|
| MeSH Number(s) |
D12.776.157.125.825.249 D12.776.543.990.850.249
|
| Concept/Terms |
Synaptotagmin I- Synaptotagmin I
- p65 Protein (Synaptotagmin I)
- Synaptic Vesicle Protein p65
- Synaptotagmin 1
|
Below are MeSH descriptors whose meaning is more general than "Synaptotagmin I".
Below are MeSH descriptors whose meaning is more specific than "Synaptotagmin I".
This graph shows the total number of publications written about "Synaptotagmin I" by people in this website by year, and whether "Synaptotagmin I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synaptotagmin I" by people in Profiles.
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Yamada K, Hannya Y, Oikawa T, Yoshida A, Katagiri K, Yoshida S, Koizumi R, Tago N, Shimoyama Y, Kawamura A, Mochimaru Y, Eto K, Yoshida K. Extended-Synaptotagmin 1 Enhances Liver Cancer Progression Mediated by the Unconventional Secretion of Cytosolic Proteins. Molecules. 2023 May 11; 28(10).
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Alicea D, Perez M, Maldonado C, Dominicci-Cotto C, Marie B. Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless. J Neurosci. 2017 02 22; 37(8):2203-2215.
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Bykhovskaia M. Calcium binding promotes conformational flexibility of the neuronal Ca(2+) sensor synaptotagmin. Biophys J. 2015 May 19; 108(10):2507-2520.
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Ahn KS, Sethi G, Shishodia S, Sung B, Arbiser JL, Aggarwal BB. Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway. Mol Cancer Res. 2006 Sep; 4(9):621-33.