Tumor Suppressor Proteins

"Tumor Suppressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that are normally involved in holding cellular growth in check. Deficiencies or abnormalities in these proteins may lead to unregulated cell growth and tumor development.

Descriptor ID	D025521
MeSH Number(s)	D12.776.624.776
Concept/Terms	Tumor Suppressor Proteins Tumor Suppressor Proteins Proteins, Tumor Suppressor Metastasis Suppressor Proteins Metastasis Suppressor Proteins Proteins, Metastasis Suppressor Growth Suppressor Proteins Growth Suppressor Proteins Proteins, Growth Suppressor

Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Tumor Suppressor Proteins [D12.776.624.776]

Below are MeSH descriptors whose meaning is related to "Tumor Suppressor Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tumor Suppressor Proteins" by people in this website by year, and whether "Tumor Suppressor Proteins" was a major or minor topic of these publications.

Bar chart showing 130 publications over 24 distinct years, with a maximum of 10 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	1	1
1999	1	0	1
2000	1	2	3
2001	2	3	5
2002	2	4	6
2003	1	4	5
2004	1	4	5
2005	6	1	7
2006	3	2	5
2007	2	3	5
2008	3	3	6
2009	6	3	9
2010	5	2	7
2011	5	5	10
2012	4	3	7
2013	3	3	6
2014	5	2	7
2015	8	0	8
2016	5	2	7
2017	5	2	7
2018	4	5	9
2019	1	1	2
2020	0	1	1

Below are the most recent publications written about "Tumor Suppressor Proteins" by people in Profiles.

Lee HJ, Pham T, Chang MT, Barnes D, Cai AG, Noubade R, Totpal K, Chen X, Tran C, Hagenbeek T, Wu X, Eastham-Anderson J, Tao J, Lee W, Bastian BC, Carbone M, Webster JD, Dey A. The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma. Cancer Res. 2020 04 15; 80(8):1656-1668.

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Carbone M, Adusumilli PS, Alexander HR, Baas P, Bardelli F, Bononi A, Bueno R, Felley-Bosco E, Galateau-Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI. Mesothelioma: Scientific clues for prevention, diagnosis, and therapy. CA Cancer J Clin. 2019 09; 69(5):402-429.

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Schunke KJ, Walton CB, Veal DR, Mafnas CT, Anderson CD, Williams AL, Shohet RV. Protein kinase C binding protein 1 inhibits hypoxia-inducible factor-1 in the heart. Cardiovasc Res. 2019 07 01; 115(8):1332-1342.

View in: PubMed
Affar EB, Carbone M. BAP1 regulates different mechanisms of cell death. Cell Death Dis. 2018 11 19; 9(12):1151.

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Coghill AE, Bellizzi AM, Lynch CF, Shiels MS, Selk FR, Gillison M, Hernandez BY, Chan OTM, Engels EA. Pathology Characterization and Detection of Human Papillomavirus Type 16 in Rectal Squamous Cell Carcinomas. Clin Gastroenterol Hepatol. 2019 09; 17(10):2129-2131.

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Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, Yang H, Carbone M, Therrien M, Affar EB. Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1. Nat Commun. 2018 10 22; 9(1):4385.

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Peng Y, Zhang X, Lin H, Deng S, Huang Y, Qin Y, Feng X, Yan R, Zhao Y, Cheng Y, Wei Y, Wang J, Chen W, Fan X, Ashktorab H, Smoot D, Meltzer SJ, Li S, Zhang Z, Jin Z. Inhibition of miR-194 suppresses the Wnt/ß-catenin signalling pathway in gastric cancer. Oncol Rep. 2018 Dec; 40(6):3323-3334.

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Moses-Fynn E, Tang W, Beyene D, Apprey V, Copeland R, Kanaan Y, Kwabi-Addo B. Correlating blood-based DNA methylation markers and prostate cancer risk in African-American men. PLoS One. 2018; 13(9):e0203322.

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Choi W, Kim J, Park J, Lee DH, Hwang D, Kim JH, Ashktorab H, Smoot D, Kim SY, Choi C, Koh GY, Lim DS. YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC. Cancer Res. 2018 06 15; 78(12):3306-3320.

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Khan F, Ricks-Santi LJ, Zafar R, Kanaan Y, Naab T. Expression of p27 and c-Myc by immunohistochemistry in breast ductal cancers in African American women. Ann Diagn Pathol. 2018 Jun; 34:170-174.

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