"Protein Footprinting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A method for determining points of contact between interacting proteins or binding sites of proteins to nucleic acids. Protein footprinting utilizes a protein cutting reagent or protease. Protein cleavage is inhibited where the proteins, or nucleic acids and protein, contact each other. After completion of the cutting reaction, the remaining peptide fragments are analyzed by electrophoresis.
| Descriptor ID |
D023302
|
| MeSH Number(s) |
E05.196.700.690 E05.393.760.705.685.690
|
| Concept/Terms |
Protein Footprints- Protein Footprints
- Footprint, Protein
- Protein Footprint
- Footprints, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Footprinting".
Below are MeSH descriptors whose meaning is more specific than "Protein Footprinting".
This graph shows the total number of publications written about "Protein Footprinting" by people in this website by year, and whether "Protein Footprinting" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Footprinting" by people in Profiles.
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Molina MP, Cain C, Bargonetti J. In vivo footprinting and DNA affinity chromatography for analysis of p53 DNA binding ability. Methods Mol Biol. 2003; 234:151-70.