Calcium Signaling

"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.

Descriptor ID	D020013
MeSH Number(s)	G02.111.820.800.100 G03.143.500.100 G04.835.800.100
Concept/Terms	Calcium Signaling Calcium Signaling Calcium Signalings Signaling, Calcium Signalings, Calcium Calcium Waves Calcium Waves Calcium Wave Wave, Calcium Waves, Calcium Calcium Oscillations Calcium Oscillation Oscillation, Calcium Oscillations, Calcium Calcium Spikes Calcium Spikes Calcium Spike Spike, Calcium Spikes, Calcium Calcium Puffs Calcium Puffs Calcium Puff Puff, Calcium Puffs, Calcium Calcium Sparks Calcium Sparks Calcium Spark Spark, Calcium Sparks, Calcium

Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Second Messenger Systems [G02.111.820.800]
Calcium Signaling [G02.111.820.800.100]
Metabolism [G03]
Biological Transport [G03.143]
Ion Transport [G03.143.500]
Calcium Signaling [G03.143.500.100]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Second Messenger Systems [G04.835.800]
Calcium Signaling [G04.835.800.100]

Below are MeSH descriptors whose meaning is related to "Calcium Signaling".

Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".

Calcium Signaling
Excitation Contraction Coupling

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.

Bar chart showing 93 publications over 23 distinct years, with a maximum of 8 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	2	2
2002	4	1	5
2003	3	3	6
2004	3	2	5
2005	3	4	7
2006	3	4	7
2007	3	4	7
2008	3	4	7
2010	2	0	2
2011	1	3	4
2012	1	1	2
2013	2	5	7
2014	3	5	8
2015	2	4	6
2016	1	0	1
2017	3	2	5
2018	0	2	2
2019	2	0	2
2020	1	0	1
2021	2	0	2
2022	1	1	2
2023	0	1	1
2024	1	1	2

Below are the most recent publications written about "Calcium Signaling" by people in Profiles.

Yanagihara AA, Giglio ML, Hurwitz K, Kadler R, Espino SS, Raghuraman S, Olivera BM. Elucidation of Medusozoan (Jellyfish) Venom Constituent Activities Using Constellation Pharmacology. Toxins (Basel). 2024 10 17; 16(10).

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Novelli F, Yoshikawa Y, Vitto VAM, Modesti L, Minaai M, Pastorino S, Emi M, Kim JH, Kricek F, Bai F, Onuchic JN, Bononi A, Suarez JS, Tanji M, Favaron C, Zolondick AA, Xu R, Takanishi Y, Wang Z, Sakamoto G, Gaudino G, Grzymski J, Grosso F, Schrump DS, Pass HI, Atanesyan L, Smout J, Savola S, Sarin KY, Abolhassani H, Hammarstr?m L, Pan-Hammarstr?m Q, Giorgi C, Pinton P, Yang H, Carbone M. Germline BARD1 variants predispose to mesothelioma by impairing DNA repair and calcium signaling. Proc Natl Acad Sci U S A. 2024 Jul 16; 121(29):e2405231121.

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Lewis KJ, Boorman-Padgett JF, Castaneda M, Spray DC, Thi MM, Schaffler MB. A Fluorescent Intravital Imaging Approach to Study Load-Induced Calcium Signaling Dynamics in Mouse Osteocytes. J Vis Exp. 2023 02 24; (192).

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Gross S, Hooper R, Tomar D, Armstead AP, Shanas N, Mallu P, Joshi H, Ray S, Chong PL, Astsaturov I, Farma JM, Cai KQ, Chitrala KN, Elrod JW, Zaidi MR, Soboloff J. Suppression of Ca2+ signaling enhances melanoma progression. EMBO J. 2022 10 04; 41(19):e110046.

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Ramaccini D, Giorgi C, Matter ML. Measuring Mitochondrial Calcium Fluxes in Cardiomyocytes upon Mechanical Stretch-Induced Hypertrophy. Methods Mol Biol. 2022; 2475:215-222.

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Lewis KJ, Cabahug-Zuckerman P, Boorman-Padgett JF, Basta-Pljakic J, Louie J, Stephen S, Spray DC, Thi MM, Seref-Ferlengez Z, Majeska RJ, Weinbaum S, Schaffler MB. Estrogen depletion on In vivo osteocyte calcium signaling responses to mechanical loading. Bone. 2021 11; 152:116072.

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Shimada BK, Yorichika N, Higa JK, Baba Y, Kobayashi M, Aoyagi T, Suhara T, Matsui T. mTOR-mediated calcium transients affect cardiac function in ex vivo ischemia-reperfusion injury. Physiol Rep. 2021 03; 9(6):e14807.

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Zhang R, Jones MM, Dornsife RE, Wu T, Sivaraman V, Tarran R, Onyenwoke RU. JUUL e-liquid exposure elicits cytoplasmic Ca2+ responses and leads to cytotoxicity in cultured airway epithelial cells. Toxicol Lett. 2021 Feb 01; 337:46-56.

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Lange I, Koster J, Koomoa DT. Calcium signaling regulates fundamental processes involved in Neuroblastoma progression. Cell Calcium. 2019 09; 82:102052.

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Marciel MP, Hoffmann PR. Molecular Mechanisms by Which Selenoprotein K Regulates Immunity and Cancer. Biol Trace Elem Res. 2019 Nov; 192(1):60-68.

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