"Protein Splicing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The excision of in-frame internal protein sequences (INTEINS) of a precursor protein, coupled with ligation of the flanking sequences (EXTEINS). Protein splicing is an autocatalytic reaction and results in the production of two proteins from a single primary translation product: the intein and the mature protein.
| Descriptor ID |
D019154
|
| MeSH Number(s) |
G02.111.660.871.790.600.700 G02.111.691.600.700 G03.734.871.790.600.700 G05.308.670.600.700
|
| Concept/Terms |
Protein Splicing- Protein Splicing
- Protein Splicings
- Splicing, Protein
- Splicings, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Splicing".
Below are MeSH descriptors whose meaning is more specific than "Protein Splicing".
This graph shows the total number of publications written about "Protein Splicing" by people in this website by year, and whether "Protein Splicing" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Splicing" by people in Profiles.
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Han Z, Su WW. Intein-mediated assembly of tunable scaffoldins for facile synthesis of designer cellulosomes. Appl Microbiol Biotechnol. 2018 Feb; 102(3):1331-1342.
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Zhang B, Rapolu M, Liang Z, Han Z, Williams PG, Su WW. A dual-intein autoprocessing domain that directs synchronized protein co-expression in both prokaryotes and eukaryotes. Sci Rep. 2015 Feb 25; 5:8541.
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Ayers B, Blaschke UK, Camarero JA, Cotton GJ, Holford M, Muir TW. Introduction of unnatural amino acids into proteins using expressed protein ligation. Biopolymers. 1999; 51(5):343-54.
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Holford M, Muir TW. Adding 'splice' to protein engineering. Structure. 1998 Aug 15; 6(8):951-6.