"DNA Footprinting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
Descriptor ID |
D018983
|
MeSH Number(s) |
E05.393.300
|
Concept/Terms |
DNA Footprinting- DNA Footprinting
- DNA Footprintings
- Footprinting, DNA
- Footprintings, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Footprinting".
Below are MeSH descriptors whose meaning is more specific than "DNA Footprinting".
This graph shows the total number of publications written about "DNA Footprinting" by people in this website by year, and whether "DNA Footprinting" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
1998 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2007 | 0 | 2 | 2 |
2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Footprinting" by people in Profiles.
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Dash C, Scarth BJ, Badorrek C, G?tte M, Le Grice SF. Examining the ribonuclease H primer grip of HIV-1 reverse transcriptase by charge neutralization of RNA/DNA hybrids. Nucleic Acids Res. 2008 Nov; 36(20):6363-71.
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Yoshioka H, Geyer CB, Hornecker JL, Patel KT, McCarrey JR. In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis. Mol Cell Biol. 2007 Nov; 27(22):7871-85.
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Gomos-Klein J, Harrow F, Alarc?n J, Ortiz BD. CTCF-independent, but not CTCF-dependent, elements significantly contribute to TCR-alpha locus control region activity. J Immunol. 2007 Jul 15; 179(2):1088-95.
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Madiraju MV, Moomey M, Neuenschwander PF, Muniruzzaman S, Yamamoto K, Grimwade JE, Rajagopalan M. The intrinsic ATPase activity of Mycobacterium tuberculosis DnaA promotes rapid oligomerization of DnaA on oriC. Mol Microbiol. 2006 Mar; 59(6):1876-90.
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Correa NE, Klose KE. Characterization of enhancer binding by the Vibrio cholerae flagellar regulatory protein FlrC. J Bacteriol. 2005 May; 187(9):3158-70.
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Solorzano-Vargas RS, Wang J, Jiang L, Tsai HV, Ontiveros LO, Vazir MA, Aguilera RJ, Mart?n MG. Multiple transcription factors in 5'-flanking region of human polymeric Ig receptor control its basal expression. Am J Physiol Gastrointest Liver Physiol. 2002 Aug; 283(2):G415-25.
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Ortiz BD, Harrow F, Cado D, Santoso B, Winoto A. Function and factor interactions of a locus control region element in the mouse T cell receptor-alpha/Dad1 gene locus. J Immunol. 2001 Oct 01; 167(7):3836-45.
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Xiao G, White D, Bargonetti J. p53 binds to a constitutively nucleosome free region of the mdm2 gene. Oncogene. 1998 Mar 05; 16(9):1171-81.
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Saleque S, Singh M, Little RD, Giannini SL, Michaelson JS, Birshtein BK. Dyad symmetry within the mouse 3' IgH regulatory region includes two virtually identical enhancers (C alpha3'E and hs3). J Immunol. 1997 May 15; 158(10):4780-7.